Current Protein Identity:P52952 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3RKQ NKX2.5 Homeodomain dimer bound to ANF-242 DNA Deposited 2011-04-18 Assembly 1 Protein–DNA Homooligomer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers
Chain A 138–194(57 aa) Fragment:Homeodomain, UNP residues 138-194
Chain B 138–194(57 aa) Fragment:Homeodomain, UNP residues 138-194
Mutation:C193S Mutation:C193S MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;50mM Tris pH 7.0, 5mM MgCl2, 15% polyethylene glycol monomethyl ether 550 , VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.70 Å R-free 0.257
4S0H TBX5 DB, NKX2.5 HD, ANF DNA Complex Deposited 2014-12-31 Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers
Chain B 142–194(53 aa) Fragment:HD (UNP residues 142-194)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.82 Å R-free 0.247
4S0H TBX5 DB, NKX2.5 HD, ANF DNA Complex Deposited 2014-12-31 Assembly 2 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers
Chain F 142–194(53 aa) Fragment:HD (UNP residues 142-194)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.82 Å R-free 0.247
6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain O 137–197(61 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
Resolution 2.10 Å R-free 0.225
6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 Assembly 2 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain M 137–197(61 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
Resolution 2.10 Å R-free 0.225
6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 Assembly 3 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain N 137–197(61 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
Resolution 2.10 Å R-free 0.225
6WC5 Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain I 140–196(57 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;291 K;100 mM HEPES pH 7.0, 18% PEG 2000
Resolution 2.90 Å R-free 0.251
6WC5 Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 Assembly 2 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain N 140–196(57 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION;291 K;100 mM HEPES pH 7.0, 18% PEG 2000
Resolution 2.90 Å R-free 0.251