Current Protein Identity:P52952
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3RKQ NKX2.5 Homeodomain dimer bound to ANF-242 DNA Deposited 2011-04-18 | Assembly 1 Protein–DNA Homooligomer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain A
138–194(57 aa)
Fragment:Homeodomain, UNP residues 138-194
Chain B
138–194(57 aa)
Fragment:Homeodomain, UNP residues 138-194
|
Mutation:C193S Mutation:C193S | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;293 K;50mM Tris pH 7.0, 5mM MgCl2, 15% polyethylene glycol monomethyl ether 550 , VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.70 Å R-free 0.257 |
| 4S0H TBX5 DB, NKX2.5 HD, ANF DNA Complex Deposited 2014-12-31 | Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain B
142–194(53 aa)
Fragment:HD (UNP residues 142-194)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.82 Å R-free 0.247 |
| 4S0H TBX5 DB, NKX2.5 HD, ANF DNA Complex Deposited 2014-12-31 | Assembly 2 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain F
142–194(53 aa)
Fragment:HD (UNP residues 142-194)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 2.82 Å R-free 0.247 |
| 6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 | Assembly 1 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain O
137–197(61 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
|
Resolution 2.10 Å R-free 0.225 |
| 6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 | Assembly 2 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain M
137–197(61 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
|
Resolution 2.10 Å R-free 0.225 |
| 6WC2 Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 | Assembly 3 Insufficient information Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain N
137–197(61 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;291 K;0.15 M DL-Malic acid pH 7.0, 20% Polyethylene glycol 3350
|
Resolution 2.10 Å R-free 0.225 |
| 6WC5 Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 | Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain I
140–196(57 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;291 K;100 mM HEPES pH 7.0, 18% PEG 2000
|
Resolution 2.90 Å R-free 0.251 |
| 6WC5 Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex Deposited 2020-03-29 | Assembly 2 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain N
140–196(57 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;291 K;100 mM HEPES pH 7.0, 18% PEG 2000
|
Resolution 2.90 Å R-free 0.251 |