Current Protein Identity:P53778
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1CM8 PHOSPHORYLATED MAP KINASE P38-GAMMA Deposited 1999-05-17 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–367(367 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7;pH 7.0, VAPOR DIFFUSION
|
Resolution 2.40 Å R-free 0.283 |
| 1CM8 PHOSPHORYLATED MAP KINASE P38-GAMMA Deposited 1999-05-17 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–367(367 aa)
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7;pH 7.0, VAPOR DIFFUSION
|
Resolution 2.40 Å R-free 0.283 |
| 4QUM Crystal structure of PTPN3 (PTPH1) in complex with a dually phosphorylated MAPK12 peptide Deposited 2014-07-10 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
182–190(9 aa)
Fragment:Activation loop (UNP RESIDUES 182-190)
|
Mutation:W190R Non-standard monomer:Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;0.1M Tris-HCl, 30% PEG 8000, 5% glycerol, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.52 Å R-free 0.245 |
| 6UNA Crystal structure of inactive p38gamma Deposited 2019-10-11 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
7–367(361 aa)
|
Mutation:Q31R | GOL GLYCEROL × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7.7;298 K;2.4M Ammonium sulfate, 50mM TRIS pH 7.7.
|
Resolution 2.55 Å R-free 0.245 |
| 6UNA Crystal structure of inactive p38gamma Deposited 2019-10-11 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
7–367(361 aa)
|
Mutation:Q31R | GOL GLYCEROL × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION;pH 7.7;298 K;2.4M Ammonium sulfate, 50mM TRIS pH 7.7.
|
Resolution 2.55 Å R-free 0.245 |
| 7CGA Crystal structure of human unphosphorylated p38gamma Deposited 2020-06-30 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
9–353(345 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8;291 K;1.9 M Sodium Malonate
|
Resolution 3.15 Å R-free 0.218 |
| 7CGA Crystal structure of human unphosphorylated p38gamma Deposited 2020-06-30 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
9–353(345 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8;291 K;1.9 M Sodium Malonate
|
Resolution 3.15 Å R-free 0.218 |
| 7CGA Crystal structure of human unphosphorylated p38gamma Deposited 2020-06-30 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
9–353(345 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8;291 K;1.9 M Sodium Malonate
|
Resolution 3.15 Å R-free 0.218 |
| 7CGA Crystal structure of human unphosphorylated p38gamma Deposited 2020-06-30 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
9–353(345 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8;291 K;1.9 M Sodium Malonate
|
Resolution 3.15 Å R-free 0.218 |