Current Protein Identity:P61978
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1J5K COMPLEX OF THE KH3 DOMAIN OF HNRNP K WITH A SINGLE_STRANDED 10MER DNA OLIGONUCLEOTIDE Deposited 2002-05-13 | Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: dimeric(2) Consistent with all polymers |
Chain A
379–463(85 aa)
Fragment:KH3 domain, RESIDUES 379-463, NUMBERED 5-89
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8;308 K;Ionic strength (raw mmCIF value) 50 mM SODIUM PHOSPHATE
|
Resolution not provided |
| 1KHM C-TERMINAL KH DOMAIN OF HNRNP K (KH3) Deposited 1999-01-07 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
375–463(89 aa)
Fragment:C-TERMINAL KH DOMAIN, RESIDUES 379-463 OF FULL LENGTH HNRNP K
|
Mutation:G26R | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 5.5;300 K;Ionic strength (raw mmCIF value) 5 mM;Pressure 1
|
Resolution not provided |
| 1ZZI Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA Deposited 2005-06-14 | Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: dimeric(2) Consistent with all polymers |
Chain A
385–463(79 aa)
Fragment:KH3 domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;294 K;PEG 4000, TRIS HCl, MAGNESIUM CHLORIDE, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
|
Resolution 1.80 Å R-free 0.240 |
| 1ZZI Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA Deposited 2005-06-14 | Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: dimeric(2) Consistent with all polymers |
Chain B
385–463(79 aa)
Fragment:KH3 domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;294 K;PEG 4000, TRIS HCl, MAGNESIUM CHLORIDE, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
|
Resolution 1.80 Å R-free 0.240 |
| 1ZZJ Structure of the third KH domain of hnRNP K in complex with 15-mer ssDNA Deposited 2005-06-14 | Assembly 1 Protein–DNA Homooligomer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain A
385–463(79 aa)
Fragment:KH3 domain
Chain B
385–463(79 aa)
Fragment:KH3 domain
Chain C
385–463(79 aa)
Fragment:KH3 domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;294 K;PEG 8000, SODIUM ACETATE, MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K
|
Resolution 2.30 Å R-free 0.283 |
| 1ZZK Crystal Structure of the third KH domain of hnRNP K at 0.95A resolution Deposited 2005-06-14 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
385–463(79 aa)
Fragment:KH3 domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;294 K;ammonium sulphate, PEG 400, Tris-HCl, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 294K
|
Resolution 0.95 Å R-free 0.127 |
| 7CRU hnRNPK NLS in complex with Importin alpha 1 (KPNA2) Deposited 2020-08-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
18–38(21 aa)
|
Not recorded | ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;293 K;0.1 M Ammonium Acetate, 0.1 M Bis-Tris pH 5.5, 17% w/v PEG 10000
|
Resolution 2.80 Å R-free 0.240 |
| 7CRU hnRNPK NLS in complex with Importin alpha 1 (KPNA2) Deposited 2020-08-14 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
18–38(21 aa)
|
Not recorded | ACT ACETATE ION × 4 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;293 K;0.1 M Ammonium Acetate, 0.1 M Bis-Tris pH 5.5, 17% w/v PEG 10000
|
Resolution 2.80 Å R-free 0.240 |
| 7RJK Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with hnRNPK Deposited 2021-07-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
57–66(10 aa)
Fragment:UNP residues 57-66
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.6;292 K;2.0 M ammonium sulfate, 0.1 M sodium citrate tribasic dihydrate, 0.2 M potassium/sodium tartrate tetrahydrate
|
Resolution 1.85 Å R-free 0.217 |
| 7RJK Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with hnRNPK Deposited 2021-07-21 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
57–66(10 aa)
Fragment:UNP residues 57-66
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 2 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.6;292 K;2.0 M ammonium sulfate, 0.1 M sodium citrate tribasic dihydrate, 0.2 M potassium/sodium tartrate tetrahydrate
|
Resolution 1.85 Å R-free 0.217 |
| 7RJO Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with hnRNPK Deposited 2021-07-21 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
57–66(10 aa)
Fragment:UNP residues 57-66
|
Non-standard monomer:Yes (specific site not provided by mmCIF) | NA SODIUM ION × 1 GOL GLYCEROL × 2 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.5;292 K;25% w/v PEG3350, 0.2 M ammonium acetate, 0.1 M Bis-Tris
|
Resolution 1.38 Å R-free 0.198 |