Current Protein Identity：Q06455
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1WQ6 The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity Deposited 2004-09-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
335–403（69 aa）
Fragment：NHR2 domain
Chain B
335–403（69 aa）
Fragment：NHR2 domain
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.6；293 K；100mM Na citrate (pH 5.6), 100mM MgCl2, 30% MPD, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.00 Å R-free 0.270 |
| 2DJ8 Solution Structure of zf-MYND Domain of Protein CBFA2TI (Protein MTG8) Deposited 2006-03-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
449–450（2 aa）
Fragment：zf-MYND
|
Not recorded | ZN ZINC ION × 2 | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 120；Pressure ambient
NMR sample composition
0.95mM zf-MYND domain, U-13C, 15N; 20mM d-Tris_HCl (pH 7.0); 100mM NaCl; 1mM d-DTT, 0.02% NaN3; 0.05mM ZnCl2; 1mM IDA; 90% H2O, 10% D20 | 90% H2O, 10% D20
|
Resolution not provided |
| 2KNH The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide Deposited 2009-08-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
119–216（98 aa）
Fragment：eTAFH domain (UNP residues 119-216)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6；303 K；Ionic strength (raw mmCIF value) 350；Pressure ambient
NMR sample composition
25 mM Bis-Tris, 1 mM EDTA, 350 mM sodium chloride, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2KYG Structure of the AML1-ETO Nervy Domain - PKA(RIIa) complex and its contribution to AML1-ETO activity Deposited 2010-05-25 | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count |
Chain C
437–467（31 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 4；303 K；Ionic strength (raw mmCIF value) 0.0；Pressure ambient
NMR sample composition
2 mM [U-99% 13C; U-99% 15N] NHR3, 2 mM [U-99% 13C; U-99% 15N] PKA(RIIa), 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2OD1 Solution structure of the MYND domain from human AML1-ETO Deposited 2006-12-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
510–559（50 aa）
Fragment：MYND domain
|
Not recorded | ZN ZINC ION × 2 | SOLUTION NMR |
NMR measurement conditions
pH 6.8；303 K；Pressure 1
NMR sample composition
1-2mM protein, 25mM Bis-Tris, 5mM DTT, 50uM ZnCl2, 95% H20, 5% D2O | 95% H20, 5% D2O
|
Resolution not provided |
| 2ODD Solution structure of the MYND domain from AML1-ETO complexed with SMRT, a corepressor Deposited 2006-12-22 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
510–559（50 aa）
Fragment：MYND domain (AML1-ETO, residues 658-707)
|
Not recorded | ZN ZINC ION × 2 | SOLUTION NMR |
NMR measurement conditions
pH 6.8；303 K；Pressure 1
NMR sample composition
2mM SMRT-MYND, 25mM Bis-Tris, pH 6.8, 50uM ZnCl2, 1mM DTT, 95%H2O, 5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2PP4 Solution Structure of ETO-TAFH refined in explicit solvent Deposited 2007-04-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
119–225（107 aa）
Fragment：TAFH domain, residues 119-225
|
Mutation：F136Y | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；293 K；Pressure ambient
NMR sample composition
1.1 mM protein, 200 mM phosphate buffer, 95% H2O, 5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 4JOL Complex structure of AML1-ETO NHR2 domain with HEB fragment Deposited 2013-03-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
338–400（63 aa）
Fragment：NHR2 domain of AML1-ETO (unp residues 338-400)
Chain C
338–400（63 aa）
Fragment：NHR2 domain of AML1-ETO (unp residues 338-400)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；0.1 mM Tris, 20% ETHANOL, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.91 Å R-free 0.252 |
| 4JOL Complex structure of AML1-ETO NHR2 domain with HEB fragment Deposited 2013-03-18 | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
338–400（63 aa）
Fragment：NHR2 domain of AML1-ETO (unp residues 338-400)
Chain D
338–400（63 aa）
Fragment：NHR2 domain of AML1-ETO (unp residues 338-400)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；0.1 mM Tris, 20% ETHANOL, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.91 Å R-free 0.252 |