Current Protein Identity：Q0VGL1
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain F
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain H
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 5 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain B
1–99（99 aa）
Chain D
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5VOK Crystal structure of the C7orf59-HBXIP dimer Deposited 2017-05-03 | Assembly 6 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain F
1–99（99 aa）
Chain H
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；291.15 K；4M sodium formate, 5%(v/v) glycerol and 0.01M barium chloride (as additive).
|
Resolution 2.89 Å R-free 0.312 |
| 5X6U Crystal structure of human heteropentameric complex Deposited 2017-02-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；Tris-HCl, 2-propanol, 1,6-hexandiol, 1,4-butandiol, 1-butanol, 1,3-propanediol, PEG 100, PEG 3350, 2-Methyl-2,4-pentanediol
|
Resolution 2.40 Å R-free 0.232 |
| 5X6V Crystal structure of human heteroheptameric complex Deposited 2017-02-23 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | NA SODIUM ION × 1 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；sodium citrate, ammonium acetate, PEG 4000
|
Resolution 2.02 Å R-free 0.243 |
| 5Y38 Crystal structure of C7orf59-HBXIP complex Deposited 2017-07-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–99（99 aa）
Fragment：Roadblock domain
|
Not recorded | SO4 SULFATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；289 K；0.16 M ammonium sulfate, 0.08 M sodium acetate trihydrate (pH 4.6), and 20% (w/v) PEG 4000
|
Resolution 2.80 Å R-free 0.256 |
| 5Y39 Crystal structure of Ragulator complex (p18 76-145) Deposited 2017-07-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
1–99（99 aa）
Fragment：Roadblock domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Bis-Tris (pH 5.5), and 25% (w/v) PEG 3350
|
Resolution 2.65 Å R-free 0.263 |
| 5Y39 Crystal structure of Ragulator complex (p18 76-145) Deposited 2017-07-28 | Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain I
1–99（99 aa）
Fragment：Roadblock domain
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Bis-Tris (pH 5.5), and 25% (w/v) PEG 3350
|
Resolution 2.65 Å R-free 0.263 |
| 5Y3A Crystal structure of Ragulator complex (p18 49-161) Deposited 2017-07-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
1–99（99 aa）
Fragment：Roadblock domain
|
Not recorded | SO4 SULFATE ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Bis-Tris (pH 5.5), and 25% (w/v) PEG 3350
|
Resolution 2.90 Å R-free 0.288 |
| 5Y3A Crystal structure of Ragulator complex (p18 49-161) Deposited 2017-07-28 | Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain I
1–99（99 aa）
Fragment：Roadblock domain
|
Not recorded | SO4 SULFATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Bis-Tris (pH 5.5), and 25% (w/v) PEG 3350
|
Resolution 2.90 Å R-free 0.288 |
| 5YK3 human Ragulator complex Deposited 2017-10-12 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain n
6–92（87 aa）
|
Mutation：Q7A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；0.1M CHES, pH 9.5, 0.56 M sodium citrate tribasic, and 1.4 M sodium chloride
|
Resolution 3.01 Å R-free 0.285 |
| 5YK3 human Ragulator complex Deposited 2017-10-12 | Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
4–97（94 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；0.1M CHES, pH 9.5, 0.56 M sodium citrate tribasic, and 1.4 M sodium chloride
|
Resolution 3.01 Å R-free 0.285 |
| 5YK3 human Ragulator complex Deposited 2017-10-12 | Assembly 3 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain I
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；0.1M CHES, pH 9.5, 0.56 M sodium citrate tribasic, and 1.4 M sodium chloride
|
Resolution 3.01 Å R-free 0.285 |
| 5YK5 structure of the human Lamtor4-Lamtor5 complex Deposited 2017-10-12 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
9–92（84 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；0.1M Tris-HCl, pH 8.0, 3.5M sodium formate
|
Resolution 2.03 Å R-free 0.294 |
| 5YK5 structure of the human Lamtor4-Lamtor5 complex Deposited 2017-10-12 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
9–91（83 aa）
|
Mutation：E10A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；287 K；0.1M Tris-HCl, pH 8.0, 3.5M sodium formate
|
Resolution 2.03 Å R-free 0.294 |
| 6B9X Crystal structure of Ragulator Deposited 2017-10-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；292 K；0.1 M CHES pH 9.0, 40% PEG 600
|
Resolution 1.42 Å R-free 0.237 |
| 6EHP The crystal structure of the human LAMTOR complex Deposited 2017-09-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；20% [w/v] PEG 3350, 0.1M Tris/HCl pH8.5, 0.2M MgCl2, 3% 2-Methyl-2-propanol
|
Resolution 2.30 Å R-free 0.228 |
| 6EHR The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex Deposited 2017-09-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；10% [w/v] PEG 4000, 0.1M tri-sodium-citrate pH5.5, 5% [v/v] isopropanol
|
Resolution 2.90 Å R-free 0.263 |
| 6NZD Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) Deposited 2019-02-13 | Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 L8S 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE；Whatman 597
|
Resolution 3.60 Å |
| 6U62 Raptor-Rag-Ragulator complex Deposited 2019-08-29 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain G
2–99（98 aa）
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.18 Å |
| 6ULG Cryo-EM structure of the FLCN-FNIP2-Rag-Ragulator complex Deposited 2019-10-08 | Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 1 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.31 Å |
| 6WJ2 CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state Deposited 2020-04-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 L8S 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione × 1 MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 6WJ3 CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the post-GAP state Deposited 2020-04-11 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain D
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 1 U3J xanthosine diphosphate × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 7T3A GATOR1-RAG-RAGULATOR - Inhibitory Complex Deposited 2021-12-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count |
Chain P
1–99（99 aa）
|
Not recorded | GNP PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å |
| 7T3B GATOR1-RAG-RAGULATOR - GAP Complex Deposited 2021-12-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count |
Chain I
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 2 AF3 ALUMINUM FLUORIDE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å |
| 7T3C GATOR1-RAG-RAGULATOR - Dual Complex Deposited 2021-12-07 | Assembly 1 Protein heterocomplex Heteromer；Protein × 17 PDB declaration: heptadecameric（17） Consistent with protein count |
Chain I
1–99（99 aa）
Chain P
1–99（99 aa）
|
Not recorded | GDP GUANOSINE-5'-DIPHOSPHATE × 3 AF3 ALUMINUM FLUORIDE × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å |
| 7UX2 cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex Deposited 2022-05-04 | Assembly 1 Protein heterocomplex Heteromer；Protein × 16 PDB declaration: hexadecameric（16） Consistent with protein count |
Chain G
1–99（99 aa）
Chain N
1–99（99 aa）
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 GDP GUANOSINE-5'-DIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å |
| 7UXC cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion Deposited 2022-05-05 | Assembly 1 Protein heterocomplex Heteromer；Protein × 18 PDB declaration: octadecameric（18） Consistent with protein count |
Chain I
1–99（99 aa）
Chain P
1–99（99 aa）
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 2 MG MAGNESIUM ION × 2 GDP GUANOSINE-5'-DIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 7UXH cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex Deposited 2022-05-05 | Assembly 1 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric（36） Consistent with protein count |
Chain K
1–99（99 aa）
Chain R
1–99（99 aa）
Chain a
1–99（99 aa）
Chain h
1–99（99 aa）
|
Not recorded | IHP INOSITOL HEXAKISPHOSPHATE × 2 GTP GUANOSINE-5'-TRIPHOSPHATE × 4 MG MAGNESIUM ION × 4 GDP GUANOSINE-5'-DIPHOSPHATE × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å |
| 8DHB Active FLCN GAP complex Deposited 2022-06-25 | Assembly 1 Insufficient information Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count |
Chain F
1–99（99 aa）
|
Not recorded | CZC [(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.53 Å |
| 9ED4 A composite map of mTORC1-Rag-Ragultor-4EBP1 on membrane Deposited 2024-11-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count |
Chain I
1–99（99 aa）
Chain X
1–99（99 aa）
|
Not recorded | GSP 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE × 2 MG MAGNESIUM ION × 8 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 IHP INOSITOL HEXAKISPHOSPHATE × 2 GTP GUANOSINE-5'-TRIPHOSPHATE × 2 GDP GUANOSINE-5'-DIPHOSPHATE × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.23 Å |
| 9ED6 CryoEM map of the mLST8-Rag-Ragultor subcomplex Deposited 2024-11-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain G
1–99（99 aa）
|
Not recorded | GTP GUANOSINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 GDP GUANOSINE-5'-DIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.98 Å |