Current Protein Identity:Q12509
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 6GEJ Chromatin remodeller-nucleosome complex at 3.6 A resolution. Deposited 2018-04-26 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: eicosameric(20) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 6GEN Chromatin remodeller-nucleosome complex at 4.5 A resolution. Deposited 2018-04-27 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: eicosameric(20) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å |
| 8QKU SWR1-nucleosome complex in configuration 1 Deposited 2023-09-18 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: eicosameric(20) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 8QKV SWR1-nucleosome complex in configuration 2 Deposited 2023-09-18 | Assembly 1 Protein–DNA Heteromer;Protein × 18 PDB declaration: eicosameric(20) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.70 Å |
| 8QYV SWR1-hexasome complex Deposited 2023-10-26 | Assembly 1 Protein–DNA Heteromer;Protein × 17 PDB declaration: 19-meric(19) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å |
| 8QZ0 SWR1-hexasome-dimer complex Deposited 2023-10-26 | Assembly 1 Protein–DNA Heteromer;Protein × 20 PDB declaration: 22-meric(22) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 9B1D Cryo-EM structure of native SWR1 bound to DNA (composite structure) Deposited 2024-03-13 | Assembly 1 Protein–DNA Heteromer;Protein × 10 PDB declaration: 12-meric(12) Consistent with all polymers |
Chain C
1–438(438 aa)
|
Not recorded | AGS PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER × 4 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 4 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6;20 mM HEPES pH 7.6, 0.2 mM EDTA, 2 mM MgCl2, 100 mM NaCl, 0.01% IGEPAL CA-630, 3.5% glycerol, and 0.25 mM TCEP, 1 mM ATP-gamma-s, 0.05% glutaraldehyde.
cryo-EM vitrification conditions
Cryogen ETHANE;6 second blot time and blot force of 12.
|
Resolution 3.30 Å |
| 9B1E Cryo-EM structure of native SWR1 bound to nucleosome (composite structure) Deposited 2024-03-13 | Assembly 1 Protein–DNA Heteromer;Protein × 19 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain C
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.6;80 nM SWR1, 160 nM nucleosomes, 1 mM ADP, 10 mM NaF, 8 mM BeCl2, 0.05% glutaraldehyde, 20 mM HEPES-KOH pH 7.6, 1.5 mM MgCl2, 0.25 mM TCEP, 0.01% IGEPAL CA-630, 1% glycerol
cryo-EM vitrification conditions
Cryogen ETHANE;3 second blot time and blot force of 10.
|
Resolution 4.40 Å |
| 9FBW SWR1 lacking Swc5 subunit in complex with hexasome Deposited 2024-05-14 | Assembly 1 Protein–DNA Heteromer;Protein × 16 PDB declaration: 18-meric(18) Consistent with all polymers |
Chain R
1–438(438 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 8 BEF BERYLLIUM TRIFLUORIDE ION × 2 MG MAGNESIUM ION × 8 ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.40 Å |