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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q14527 New Search
9PDB entries
21Biological assembly
29chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
2MZN NMR structure of the HLTF HIRAN domain in its DNA-bound conformation Deposited 2015-02-18 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 51–171（121 aa） Fragment：UNP residues 51-171
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.8；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR sample composition 1 mM [U-13C; U-15N] protein, 20 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
4HRE Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain G 26–39（14 aa）
Chain H 26–39（14 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 3.7；293 K；0.1 M citric acid, 25% PEG 3350, pH 3.7, VAPOR DIFFUSION, SITTING DROP, temperature 293.0K
Resolution 2.79 Å R-free 0.296
4HRE Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 2 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain K 26–39（14 aa）
Chain L 26–39（14 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 3.7；293 K；0.1 M citric acid, 25% PEG 3350, pH 3.7, VAPOR DIFFUSION, SITTING DROP, temperature 293.0K
Resolution 2.79 Å R-free 0.296
4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 26–39（14 aa）
Chain D 26–39（14 aa）
Not recorded SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
Resolution 3.00 Å R-free 0.263
4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 26–39（14 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
Resolution 3.00 Å R-free 0.263
4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain D 26–39（14 aa）
Not recorded SO4 SULFATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
Resolution 3.00 Å R-free 0.263
4HRH Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide Deposited 2012-10-27 Assembly 4 Insufficient information Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain C 26–39（14 aa）
Chain D 26–39（14 aa）
Not recorded SO4 SULFATE ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1 M MES, 1.6 M (NH4)2SO4, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 293.0K
Resolution 3.00 Å R-free 0.263
4S0N Crystal Structure of HLTF HIRAN Domain bound to DNA Deposited 2015-01-02 Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: octameric（8） Consistent with all polymers
Chain A 55–180（126 aa） Fragment：HIRAN Domain, UNP residues 55-180
Chain B 55–180（126 aa） Fragment：HIRAN Domain, UNP residues 55-180
Chain C 55–180（126 aa） Fragment：HIRAN Domain, UNP residues 55-180
Chain D 55–180（126 aa） Fragment：HIRAN Domain, UNP residues 55-180
Not recorded TMP THYMIDINE-5'-PHOSPHATE × 2 GOL GLYCEROL × 2 NA SODIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；289.15 K；25% PEG 4000, 250 mM sodium acetate trihydrate, 100 mM Tris-HCl pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 289.15K
Resolution 1.50 Å R-free 0.185
4XZF Crystal structure of HIRAN domain of human HLTF in complex with DNA Deposited 2015-02-04 Assembly 1 Protein–DNA Monomer；Protein × 1 PDB declaration: trimeric（3） Consistent with all polymers
Chain A 58–174（117 aa） Fragment：UNP residues 58-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350, Na acetate
Resolution 1.38 Å R-free 0.207
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 5 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 6 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain F 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 7 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain G 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 8 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain H 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
4XZG Crystal structure of HIRAN domain of human HLTF Deposited 2015-02-04 Assembly 9 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain I 57–174（118 aa） Fragment：UNP residues 57-174
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG 3350
Resolution 2.40 Å R-free 0.231
5BNH Crystal structure of the HLTF HIRAN domain with a ssDNA fragment Deposited 2015-05-26 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 55–175（121 aa） Fragment：UNP residues 55-175
Chain D 55–175（121 aa） Fragment：UNP residues 55-175
Not recorded NA SODIUM ION × 2 PO4 PHOSPHATE ION × 2 ACT ACETATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；291 K；0.1 M Sodium acetate trihydrate pH 5.0, 40% 2-Methyl-2,4-pentanediol
Resolution 1.70 Å R-free 0.214
5K5F NMR structure of the HLTF HIRAN domain Deposited 2016-05-23 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 51–171（121 aa） Fragment：residues 51-171
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.8；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure 1
NMR sample composition 1 mM [U-99% 13C; U-99% 15N] HLTF HIRAN domain, 20 mM sodium phosphate, 100 mM sodium chloride, 90% H2O/10% D2O | 90% H2O/10% D2O
Resolution not provided
6KCS Crystal structure of HIRAN domain of HLTF in complex with duplex DNA Deposited 2019-06-28 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 58–174（117 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；293 K；PEG
Resolution 2.10 Å R-free 0.264

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.