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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q27974 New Search
9PDB entries
12Biological assembly
36chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1N4C NMR Structure of the J-Domain and Clathrin Substrate Binding Domain of Bovine Auxilin Deposited 2002-10-30 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 737–910（174 aa） Fragment：Residues (737-845), J-Domain
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 4.5；300 K；Ionic strength (raw mmCIF value) 60mM NaCl；Pressure ambient
NMR sample composition 1.5mM Auxilin (20kD C-terminal construct) U-15N | 90% H20, 10% D2O
NMR sample composition 1.5mM Auxilin (20kD C-terminal construct) U-15N,13C | 90% H2O/10% D2O
Resolution not provided
1NZ6 Crystal Structure of Auxilin J-Domain Deposited 2003-02-16 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 810–910（101 aa） Fragment：J-Domain
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8；277 K；PEG 8000, Tris-Cl, TCEP, Glycerol, pH 8.0, microbatch under oil, temperature 277K
Resolution 2.50 Å R-free 0.268
1NZ6 Crystal Structure of Auxilin J-Domain Deposited 2003-02-16 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 810–910（101 aa） Fragment：J-Domain
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8；277 K；PEG 8000, Tris-Cl, TCEP, Glycerol, pH 8.0, microbatch under oil, temperature 277K
Resolution 2.50 Å R-free 0.268
1XI5 Clathrin D6 coat with auxilin J-domain Deposited 2004-09-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 216 PDB declaration: 216-MERIC（216） Consistent with protein count
Chain J 797–910（114 aa） Fragment：residues 797-910
Chain K 797–910（114 aa） Fragment：residues 797-910
Chain L 797–910（114 aa） Fragment：residues 797-910
Chain M 797–910（114 aa） Fragment：residues 797-910
Chain N 797–910（114 aa） Fragment：residues 797-910
Chain O 797–910（114 aa） Fragment：residues 797-910
Chain P 797–910（114 aa） Fragment：residues 797-910
Chain Q 797–910（114 aa） Fragment：residues 797-910
Chain R 797–910（114 aa） Fragment：residues 797-910
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 20MM HEPES；pH 7；20MM HEPES
cryo-EM vitrification conditions Cryogen ETHANE；VITRIFIED
Resolution 12.00 Å
1XI5 Clathrin D6 coat with auxilin J-domain Deposited 2004-09-21 Assembly 2 Protein heterocomplex Heteromer；Protein × 18 PDB declaration: octadecameric（18） Consistent with protein count
Chain J 797–910（114 aa） Fragment：residues 797-910
Chain K 797–910（114 aa） Fragment：residues 797-910
Chain L 797–910（114 aa） Fragment：residues 797-910
Chain M 797–910（114 aa） Fragment：residues 797-910
Chain N 797–910（114 aa） Fragment：residues 797-910
Chain O 797–910（114 aa） Fragment：residues 797-910
Chain P 797–910（114 aa） Fragment：residues 797-910
Chain Q 797–910（114 aa） Fragment：residues 797-910
Chain R 797–910（114 aa） Fragment：residues 797-910
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 20MM HEPES；pH 7；20MM HEPES
cryo-EM vitrification conditions Cryogen ETHANE；VITRIFIED
Resolution 12.00 Å
1XI5 Clathrin D6 coat with auxilin J-domain Deposited 2004-09-21 Assembly 3 Protein heterocomplex Heteromer；Protein × 18 PDB declaration: octadecameric（18） Consistent with protein count
Chain J 797–910（114 aa） Fragment：residues 797-910
Chain K 797–910（114 aa） Fragment：residues 797-910
Chain L 797–910（114 aa） Fragment：residues 797-910
Chain M 797–910（114 aa） Fragment：residues 797-910
Chain N 797–910（114 aa） Fragment：residues 797-910
Chain O 797–910（114 aa） Fragment：residues 797-910
Chain P 797–910（114 aa） Fragment：residues 797-910
Chain Q 797–910（114 aa） Fragment：residues 797-910
Chain R 797–910（114 aa） Fragment：residues 797-910
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 20MM HEPES；pH 7；20MM HEPES
cryo-EM vitrification conditions Cryogen ETHANE；VITRIFIED
Resolution 12.00 Å
2QWN Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-386aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi state Deposited 2007-08-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 812–905（94 aa）
Mutation：D876C PO4 PHOSPHATE ION × 1 NA SODIUM ION × 2 MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8；289 K；PEG3350, Ammonium Acetate, pH 8.0, microbatch under oil, temperature 289K
Resolution 2.40 Å R-free 0.279
2QWO Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi form #1 Deposited 2007-08-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 813–904（92 aa）
Mutation：D876C PO4 PHOSPHATE ION × 1 NA SODIUM ION × 2 MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8.5；289 K；PEG3350, Ammonium Acetate, pH 8.5, microbatch under oil, temperature 289K
Resolution 1.70 Å R-free 0.222
2QWP Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi form #2 Deposited 2007-08-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 813–904（92 aa）
Mutation：D876C PO4 PHOSPHATE ION × 1 NA SODIUM ION × 2 MG MAGNESIUM ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8.5；289 K；PEG3350, Ammonium Acetate, pH 8.5, microbatch under oil, temperature 289K
Resolution 1.75 Å R-free 0.243
2QWQ Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form Deposited 2007-08-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 813–904（92 aa）
Mutation：D876C PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8.5；289 K；PEG3350, Ammonium Acetate, pH 8.5, microbatch under oil, temperature 289K
Resolution 2.21 Å R-free 0.295
2QWR Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP intact form Deposited 2007-08-10 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 813–904（92 aa）
Mutation：D876C ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions microbatch under oil；pH 8.5；289 K；PEG3350, Ammonium Acetate, pH 8.5, microbatch under oil, temperature 289K
Resolution 2.21 Å R-free 0.294
3N0A Crystal structure of auxilin (40-400) Deposited 2010-05-13 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 40–400（361 aa） Fragment：UNP residues 40-400
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；15.5% PEG 4000, 0.1 M HEPES, pH 7.5, 0.01 M CaCl2, 0.8 M NaCl, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.20 Å R-free 0.200

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.