Current Protein Identity：Q2NKJ3
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5W2L Structure of a central domain of human Ctc1 Deposited 2017-06-06 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
716–880（165 aa）
Fragment：UNP residues 716-880
|
Not recorded | HG MERCURY (II) ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；291.15 K；0.1 M MES, pH 6.0, 20% w/v PEG2000 MME
|
Resolution 1.86 Å R-free 0.249 |
| 5W2L Structure of a central domain of human Ctc1 Deposited 2017-06-06 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
716–880（165 aa）
Fragment：UNP residues 716-880
|
Not recorded | HG MERCURY (II) ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；291.15 K；0.1 M MES, pH 6.0, 20% w/v PEG2000 MME
|
Resolution 1.86 Å R-free 0.249 |
| 6W6W Cryo-EM structure of CST bound to telomeric single-stranded DNA Deposited 2020-03-17 | Assembly 1 Protein–DNA Heteromer；Protein × 4 PDB declaration: pentameric（5） Consistent with all polymers |
Chain A
2–1217（1216 aa）
Chain B
2–1217（1216 aa）
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å |
| 7U5C Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state Deposited 2022-03-02 | Assembly 1 Protein–DNA Heteromer；Protein × 7 PDB declaration: octameric（8） Consistent with all polymers |
Chain E
1–1217（1217 aa）
|
Not recorded | ZN ZINC ION × 4 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.60 Å |
| 8D0B Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template Deposited 2022-05-26 | Assembly 1 Protein–DNA Heteromer；Protein × 7 PDB declaration: octameric（8） Consistent with all polymers |
Chain A
9–1217（1209 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5；CHAPSO is only added just before sample vitrification.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.43 Å |
| 8D0K Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC Deposited 2022-05-26 | Assembly 1 Protein–DNA Heteromer；Protein × 7 PDB declaration: octameric（8） Consistent with all polymers |
Chain A
2–1217（1216 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5；CHAPSO is only added just before sample vitrification.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.27 Å |
| 8SOJ Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA Deposited 2023-04-28 | Assembly 1 Insufficient information Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
1–1217（1217 aa）
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 8SOK Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA Deposited 2023-04-28 | Assembly 1 Insufficient information Heteromer；Protein × 5 PDB declaration: hexameric（6） Consistent with all polymers |
Chain A
1–1217（1217 aa）
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å |