Current Protein Identity：Q582V7
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 10JU Crystal Structure of serine/threonine-protein kinase (AEK1) T376D, S395D Mutant from Trypanosoma brucei (AMP-PNP) Deposited 2026-01-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
54–406（353 aa）
Fragment：residues 54-406
Chain B
54–406（353 aa）
Fragment：residues 54-406
|
Mutation：T376D, S395D Non-standard monomer：Yes (specific site not provided by mmCIF) Mutation：T376D, S395D | SO4 SULFATE ION × 11 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；291 K；Index F6 0.2M Ammonium sulfate 0.1M Bis-Tris pH 5.5 25% PEG 3350. TrbrA.01480.a.WW4.PS38793 at 13.5 mg/mL. The C-terminal tail ~60 residues was disordered in each subunit. Residue Ser 71 in subunit A contained a large amount of density near the OG atom. This was modeled as a phosphoserine (SEP) although this is not a predicted phosphorylation site. 2mM AMP-PNP and 2mM MgCl2 added prior to crystallization. Prominent AMP-PNP density in subunit B but disorder in the phosphate portion. plate 20522 F6 drop 2, Puck: PSL-0904, Cryo: 80% crystallant + 20% glycerol
|
Resolution 2.15 Å R-free 0.250 |
| 9Z8K Crystal Structure of serine/threonine-protein kinase (AEK1) from Trypanosoma brucei Deposited 2025-11-18 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
54–406（353 aa）
Fragment：residues 54-406
Chain B
54–406（353 aa）
Fragment：residues 54-406
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | SO4 SULFATE ION × 11 CL CHLORIDE ION × 10 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；291 K；IDX G2 (25% (w/v) PEG 3350, 0.1 M BIS-TRIS pH 5.5, 0.2 M lithium sulfate. TrbrA.01480.a.WW4.PS38793 at 13.5 mg/mL. The C-terminal tail ~60 residues was disordered in each subunit. Residue Ser 71 in subunit A contained a large amount of density near the OG atom. This was modeled as a phosphoserine (SEP) although this is not a predicted phosphorylation site. plate 20520 G2 drop 1, Puck: PSL-0604, Cryo: 80% crystallant + 20% glycerol
|
Resolution 2.05 Å R-free 0.235 |