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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q5MNZ6 New Search
5PDB entries
8Biological assembly
10chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
6IYY Crystal structure of human WIPI3,loop deletion mutant Deposited 2018-12-17 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 8–344（337 aa）
Mutation：DELETION OF RESIDUES 75-80 and 264-281 SO4 SULFATE ION × 7 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；pH 7；289 K；1.6M Ammonium Sulfate, 0.1M Tris-HCl
Resolution 1.80 Å R-free 0.204
6KLR Crystal structure of human WIPI3 in complex with the WIR-peptide from ATG2A Deposited 2019-07-30 Assembly 1 Insufficient information Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 8–344（337 aa）
Chain B 8–344（337 aa）
Mutation：Deletion of 75-80 and Deletion of 264-280 Mutation：Deletion of 75-80 and Deletion of 264-280 No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；289 K；0.1M Tirs-HCl, pH 8.5, 20% (v/v) Ethanol
Resolution 2.21 Å R-free 0.255
8ZQG Crystal structure of WIPI3 in complex with ATG16L1 Deposited 2024-06-02 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 8–344（337 aa）
Chain B 8–344（337 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.8；289 K；0.02 M Citric acid, 0.08 M BIS-TRIS propane (pH 8.8); 16% w/v Polyethylene glycol 3350
Resolution 2.77 Å R-free 0.233
9C9I Structure of the TSC1:WIPI3 complex Deposited 2024-06-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 12–344（333 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293.15 K；0.2 M ammonium tartrate, 20 % PEG3350, and 0.25 M sodium acetate.
Resolution 3.18 Å R-free 0.255
9C9I Structure of the TSC1:WIPI3 complex Deposited 2024-06-14 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 12–344（333 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293.15 K；0.2 M ammonium tartrate, 20 % PEG3350, and 0.25 M sodium acetate.
Resolution 3.18 Å R-free 0.255
9C9I Structure of the TSC1:WIPI3 complex Deposited 2024-06-14 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain E 12–344（333 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293.15 K；0.2 M ammonium tartrate, 20 % PEG3350, and 0.25 M sodium acetate.
Resolution 3.18 Å R-free 0.255
9C9I Structure of the TSC1:WIPI3 complex Deposited 2024-06-14 Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain G 12–344（333 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；293.15 K；0.2 M ammonium tartrate, 20 % PEG3350, and 0.25 M sodium acetate.
Resolution 3.18 Å R-free 0.255
9CE3 Structure of the TSC:WIPI3 lysosomal recruitment complex Deposited 2024-06-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count
Chain F 12–344（333 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.6；20 mM HEPES (pH 7.6), 250 mM NaCl, 2 mM DTT
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.