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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q5MQD0 New Search
31PDB entries
34Biological assembly
60chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5GNB Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 2.3 angstrom, native-SAD phasing) Deposited 2016-07-20 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 307–677（371 aa） Fragment：UNP residues 307-677
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；0.1M Tris, 24%PEG4000, 0.2M MgCl2, 4% v/v Pentaerythritol ethoxylate (3/4 EO/OH)
Resolution 2.30 Å R-free 0.219
5KWB Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 1.9 angstrom, molecular replacement) Deposited 2016-07-17 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 307–677（371 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 MG MAGNESIUM ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；291 K；0.1M Tris, 24%PEG4000, 0.2M MgCl2
Resolution 1.91 Å R-free 0.201
8DGW Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent Deposited 2022-06-24 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain G 1226–1250（25 aa） Fragment：stem helix domain, residues 1226-1250
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；0.2 M Ammonium formate, 20% (w/v) PEG 3350
Resolution 2.81 Å R-free 0.248
8DGW Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent Deposited 2022-06-24 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain I 1226–1250（25 aa） Fragment：stem helix domain, residues 1226-1250
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；0.2 M Ammonium formate, 20% (w/v) PEG 3350
Resolution 2.81 Å R-free 0.248
8DGW Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent Deposited 2022-06-24 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain J 1226–1250（25 aa） Fragment：stem helix domain, residues 1226-1250
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；0.2 M Ammonium formate, 20% (w/v) PEG 3350
Resolution 2.81 Å R-free 0.248
8DGW Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent Deposited 2022-06-24 Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain K 1226–1250（25 aa） Fragment：stem helix domain, residues 1226-1250
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；0.2 M Ammonium formate, 20% (w/v) PEG 3350
Resolution 2.81 Å R-free 0.248
8VGT Structure of the HKU1 RBD bound to the human TMPRSS2 receptor Deposited 2023-12-27 Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 320–614（295 aa） Fragment：RBD
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8Y7X Structure of HCoV-HKU1A spike in the functionally anchored-3up conformation with 3TMPRSS2 Deposited 2024-02-05 Assembly 1 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 14–1281（1268 aa）
Chain B 14–1281（1268 aa）
Chain C 14–1281（1268 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 23 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.09 Å
8Y7Y Local structure of HCoV-HKU1A spike in complex with TMPRSS2 and glycan Deposited 2024-02-05 Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1281（1268 aa）
Chain B 14–1281（1268 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 MJJ methyl 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.24 Å
8YOY Structure of HKU1A RBD with TMPRSS2 Deposited 2024-03-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 307–677（371 aa） Fragment：RBD domain
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.21 Å
9BSW Cryo-EM structure of HCoV-HKU1 Spike glycoprotein (DDA state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 36 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.06 Å
9BSX Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9O-acetyl GD3 sialoglycan (DAA state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 39 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.37 Å
9BSY Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9O-acetyl GD3 sialoglycan (DAU state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 31 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.58 Å
9BSZ Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9O-acetyl GD3 sialoglycan (AUU state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 32 A1AR2 5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranose × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.49 Å
9BT0 Cryo-EM structure of HCoV-HKU1 Spike glycoprotein (DDD state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 39 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.23 Å
9BT1 Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9O-acetyl GD3 sialoglycan (UUU state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.22 Å
9BT2 Cryo-EM structure of HCoV-HKU1 glycoprotein D1 (Down State, locally refined) Deposited 2024-05-14 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 1.93 Å
9BT9 Cryo-EM Structure of HKU1 spike D1 Domain (Active state, locally refined) Deposited 2024-05-14 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.11 Å
9BTA Cryo-EM density map of HKU1 spike glycoprotein D1 domain in complex with 9O-acetyl GD3 sialoglycan (Down_alt state, locally refined) Deposited 2024-05-14 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.39 Å
9BTB Cryo-EM density map of HKU1 spike glycoprotein D1 domain in complex with 9O-acetyl GD3 sialoglycan (Active state, locally refined) Deposited 2024-05-14 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.33 Å
9BTC Cryo-EM density map of HKU1 spike glycoprotein D1 domain in complex with 9O-acetyl GD3 sialoglycan (Up state, locally refined) Deposited 2024-05-14 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1223（1210 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.41 Å
9BTD Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9O-acetyl GD3 sialoglycan (DDA state) Deposited 2024-05-14 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 37 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.43 Å
9IZN Crystal structure of HKU1A RBD bound to TMPRSS2 Deposited 2024-08-01 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 307–677（371 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；2% v/v Tacsimate pH 7.0, 5% v/v 2-Propanol, 0.1 M Imidazole (pH 7.0) and 8% w/v Polyethylene glycol 3350
Resolution 2.40 Å R-free 0.261
9JCX Crystal structure of the HCoV-HKU1 RBD and TMPRSS2 Deposited 2024-08-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 323–609（287 aa）
Not recorded CA CALCIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；293 K；0.2 M Tris pH 7.0, 0.2 M MgCl2, 10% (w/v) Polyethylene glycol 8,000
Resolution 2.75 Å R-free 0.237
9JCY Crystal structure of the HCoV-HKU1 RBD in complex with Fab Deposited 2024-08-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 323–609（287 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 GOL GLYCEROL × 4 X-RAY DIFFRACTION
X-ray crystallization conditions EVAPORATION；293 K；0.2% (w/v) Ala-Ala, 0.2% (w/v) Ala-Gln, 0.2% (w/v) Gly-Glu, 0.2% (w/v) Gly-L-Ala, 0.2% (w/v) Gly-L-Asp, 0.2% (w/v) Gly-Sar, 0.2% (w/v) L-Carnosine, 0.2% (w/v) Leu-Ala hydrate, 0.1 M Buffer System 3 [Tris (base); BICINE] pH 8.5, 20% (v/v) PEG 500* MME, 10 % w/v PEG 20,000; for TMPRSS2:VHH77, 0.2 M sodium malonate pH 6.0, 10% (w/v) Polyethylene glycol 3,350
Resolution 1.80 Å R-free 0.203
9N12 Cryo-EM structure of HCoV-HKU1 glycoprotein (mutant T31VPR34 to GGGG) Deposited 2025-01-24 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa）
Chain B 14–1298（1285 aa）
Chain C 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 39 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.18 Å
9N13 Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain (mutant T31VPR34 to GGGG) Deposited 2025-01-24 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.34 Å
9N14 Cryo-EM structure of HCoV-HKU1 glycoprotein in complex with 9OAc-GD3(mutant T31VPR34 to GGGG) Deposited 2025-01-24 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain B 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Chain C 14–1298（1285 aa） Fragment：ectodomain (UNP residues 14-1298)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 35 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.08 Å
9N15 Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain in complex with 9OAc-GD3(mutant T31VPR34 to GGGG) Deposited 2025-01-24 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
9N16 Cryo-EM structure of HCoV-HKU1 glycoprotein (Deletion 33Pro34Arg) Deposited 2025-01-24 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa）
Chain B 14–1298（1285 aa）
Chain C 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 39 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.01 Å
9N17 Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain (Deletion 33Pro34Arg) Deposited 2025-01-24 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.09 Å
9N18 Cryo-EM structure of HCoV-HKU1 spike glycoprotein in complex with 9OAc-GD3 tetrasacchride (Deletion 33Pro34Arg) Deposited 2025-01-24 Assembly 1 Other combination Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 14–1298（1285 aa）
Chain B 14–1298（1285 aa）
Chain C 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 39 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.02 Å
9N19 Cryo-EM structure of HCoV-HKU1spike glycoprotein D1 Domain in complex with 9OAc-GD3 tetrasacchride (Deletion 33Pro34Arg) Deposited 2025-01-24 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 14–1298（1285 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 A1AR1 5-acetamido-8-O-(5-acetamido-9-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.02 Å
9OPQ TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD Deposited 2025-05-19 Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 320–509（190 aa）
Chain A 511–614（104 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.30 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.