Current Protein Identity:Q5V8Y6 New Search
Main Difference Dimensions in This Set
Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
4WRT Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) Deposited 2014-10-25 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 9;281 K;1 M LiCl, 10% PEG 6000 and 0.1 M bicine pH 9.0
Resolution 2.70 Å R-free 0.211
4WSA Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) Deposited 2014-10-26 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain B 1–752(752 aa)
Mutation:Trichoplusia ni No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 9;281 K;FluB polymerase was concentrated to 9 mg per ml (37 microM) in a buffer containing 500 mM NaCl, 50 mM Hepes pH 7.5, 5% glycerol and 2mM Tris(2-carboxyethyl)phosphine (TCEP), and mixed with 40 microM vRNA for crystallization in hanging drops at 4 C. A trigonal crystal form (FluB1) was obtained by mixing polymerase with nucleotides 5-18 of the 3 prime end and 1-14 of the 5 prime end of the vRNA in a condition containing 0.1 M bicine pH 9.0, 10% MPD.
Resolution 3.40 Å R-free 0.265
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain B 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 2 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain F 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 3 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain J 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 4 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain N 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 5 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain R 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 6 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain V 1–752(752 aa) Fragment:PB1 SUBUNIT
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 5.6;277 K;100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5FMZ Crystal structure of Influenza B polymerase with bound 5' vRNA Deposited 2015-11-10 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain E 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5;0.1 M KCL, 10 MM MGCL2, 50 MM TRIS-HCL PH 8.5 AND 30% PEG400
Resolution 3.40 Å R-free 0.277
5FMZ Crystal structure of Influenza B polymerase with bound 5' vRNA Deposited 2015-11-10 Assembly 2 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5;0.1 M KCL, 10 MM MGCL2, 50 MM TRIS-HCL PH 8.5 AND 30% PEG400
Resolution 3.40 Å R-free 0.277
5M3J Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD Deposited 2016-10-14 Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 9;277 K;FluB polymerase in a buffer containing 500 mM NaCl, 50 mM Hepes pH 7.5, 5% glycerol and 2mM Tris(2-carboxyethyl)phosphine (TCEP) was mixed with 5' and 3' ends of vRNA promoter and CTD peptide. Reservoir solution contained 0.1 M bicine pH 9.0, 10% MPD.
Resolution 3.50 Å R-free 0.268
5MSG Influenza B polymerase bound to vRNA promoter and capped RNA primer Deposited 2017-01-04 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded PO4 PHOSPHATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4;277 K;35 microM of FluB polymerase was mixed with 40 microM of the vRNA promoter and 40 microM 13-mer capped RNA primer in a buffer containing 500 mM NaCl, 50 mM HEPES pH 7.5, 5% glycerol and 2 mM TCEP. The best diffracting crystals appeared in 100 mM sodium acetate pH 3.8 - 4.0 and 150 mM di-ammonium phosphate
Resolution 3.80 Å R-free 0.267
6F5O A mechanism for the activation of the influenza virus transcriptase Deposited 2017-12-02 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.80 Å
6QCS Influenza B polymerase pre-initiation complex Deposited 2018-12-30 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6QCT Influenza B polymerase elongation complex Deposited 2018-12-30 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
6QCV Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer and CTP Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded PO4 PHOSPHATE ION × 1 CTP CYTIDINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.4;277 K;Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 14-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4. CTP was soaked for 18 hours into grown crystals at a final concentration of 5 mM in the drop.
Resolution 3.24 Å R-free 0.234
6QCW Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded PO4 PHOSPHATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.4;277 K;Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 14-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4.
Resolution 2.88 Å R-free 0.234
6QCX Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded PO4 PHOSPHATE ION × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.4;277 K;Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 15-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4.
Resolution 3.08 Å R-free 0.226
6T0W Human Influenza B polymerase recycling complex Deposited 2019-10-03 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.18 Å
7R1F Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106 Deposited 2022-02-02 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 3 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.58 Å
7Z42 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B Deposited 2022-03-03 Assembly 1 Protein–RNA Heteromer;Protein × 5 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;FluPolB PA mutant K135A at 9 mg per ml was mixed with 40 microM of nucleotides 1-13 vRNA 5prime end, 5-pAGUAGUAACAAGA-3, and 1.8 mM 28-mer CTD peptide, YSPTpSPS x 4 in a buffer containing 50 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 2 mM TCEP. Hanging drops for crystallization were set up at 20 C.
Resolution 2.42 Å R-free 0.257
7Z42 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B Deposited 2022-03-03 Assembly 2 Protein–RNA Heteromer;Protein × 5 PDB declaration: hexameric(6) Consistent with all polymers
Chain E 1–752(752 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;FluPolB PA mutant K135A at 9 mg per ml was mixed with 40 microM of nucleotides 1-13 vRNA 5prime end, 5-pAGUAGUAACAAGA-3, and 1.8 mM 28-mer CTD peptide, YSPTpSPS x 4 in a buffer containing 50 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 2 mM TCEP. Hanging drops for crystallization were set up at 20 C.
Resolution 2.42 Å R-free 0.257
7Z43 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B Deposited 2022-03-03 Assembly 1 Protein–RNA Heteromer;Protein × 5 PDB declaration: octameric(8) Consistent with all polymers
Chain BBB 1–752(752 aa)
Not recorded PO4 PHOSPHATE ION × 1 IC5 [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.4;277 K;200 mM di-ammonium phosphate, and 100 mM sodium acetate at pH 4.4
Resolution 3.12 Å R-free 0.272
8BDR Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position Deposited 2022-10-19 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 2 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
8BE0 Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position Deposited 2022-10-20 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 2 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.34 Å
8BF5 Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue Deposited 2022-10-24 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: hexameric(6) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 3 G2P PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.96 Å
8RN1 Influenza B polymerase, monomeric encapsidase with 5' cRNA hook bound Deposited 2024-01-09 Assembly 1 Protein–RNA Heteromer;Protein × 3 PDB declaration: tetrameric(4) Consistent with all polymers
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.64 Å
8RN2 Monomeric apo-influenza B polymerase, encapsidase conformation Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.89 Å
8RN3 Pseudo-symmetrical influenza B polymerase apo-dimer, encapsidase moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain B 1–752(752 aa)
Chain E 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
8RN4 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(T) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain B 1–752(752 aa)
Chain E 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.87 Å
8RN5 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(R) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain B 1–752(752 aa)
Chain D 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.88 Å
8RN6 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(E) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain B 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.82 Å
8RN7 Pseudo-symmetrical influenza B polymerase apo-dimer, core-only moeity (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain B 1–752(752 aa)
Chain D 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.09 Å
8RN8 Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S)) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain B 1–752(752 aa)
Chain E 1–752(752 aa)
Not recorded MG MAGNESIUM ION × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.92 Å
8RN9 Influenza B polymerase, replicase (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain B 1–752(752 aa)
Chain D 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.31 Å
8RNA Influenza B polymerase apo-trimer Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 10 PDB declaration: decameric(10) Consistent with protein count
Chain B 1–752(752 aa)
Chain E 1–752(752 aa)
Chain Y 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.57 Å
8RNB Influenza B polymerase, encapsidase plus 627(R) / human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count
Chain E 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.31 Å
8RNC Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer;Protein × 9 PDB declaration: nonameric(9) Consistent with protein count
Chain B 1–752(752 aa)
Chain E 1–752(752 aa)
Chain Y 1–752(752 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.52 Å