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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：Q5V8Z9 New Search
35PDB entries
44Biological assembly
54chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
4WRT Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) Deposited 2014-10-25 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: pentameric（5） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；281 K；1 M LiCl, 10% PEG 6000 and 0.1 M bicine pH 9.0
Resolution 2.70 Å R-free 0.211
4WSA Crystal structure of Influenza B polymerase bound to the vRNA promoter (FluB1 form) Deposited 2014-10-26 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: pentameric（5） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；281 K；FluB polymerase was concentrated to 9 mg per ml (37 microM) in a buffer containing 500 mM NaCl, 50 mM Hepes pH 7.5, 5% glycerol and 2mM Tris(2-carboxyethyl)phosphine (TCEP), and mixed with 40 microM vRNA for crystallization in hanging drops at 4 C. A trigonal crystal form (FluB1) was obtained by mixing polymerase with nucleotides 5-18 of the 3 prime end and 1-14 of the 5 prime end of the vRNA in a condition containing 0.1 M bicine pH 9.0, 10% MPD.
Resolution 3.40 Å R-free 0.265
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 2 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain E 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 3 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain I 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 4 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain M 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 5 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain Q 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5EPI CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT Deposited 2015-11-11 Assembly 6 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain U 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；277 K；100 MM TRI SODIUM CITRATE PH 5.6, 10 OR 100 MM NACL AND 12% MPD
Resolution 4.10 Å R-free 0.287
5FML Crystal structure of the endonuclease from the PA subunit of influenza B virus bound to the PB2 subunit NLS peptide Deposited 2015-11-06 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 1–197（197 aa） Fragment：ENDONUCLEASE DOMAIN RESIDUES 1-197
Not recorded MG MAGNESIUM ION × 2 GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；0.1 M MES PH 6.5, 25% PEG6000
Resolution 1.70 Å R-free 0.276
5FMZ Crystal structure of Influenza B polymerase with bound 5' vRNA Deposited 2015-11-10 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain D 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；0.1 M KCL, 10 MM MGCL2, 50 MM TRIS-HCL PH 8.5 AND 30% PEG400
Resolution 3.40 Å R-free 0.277
5FMZ Crystal structure of Influenza B polymerase with bound 5' vRNA Deposited 2015-11-10 Assembly 2 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；0.1 M KCL, 10 MM MGCL2, 50 MM TRIS-HCL PH 8.5 AND 30% PEG400
Resolution 3.40 Å R-free 0.277
5M3J Influenza B polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD Deposited 2016-10-14 Assembly 1 Protein–RNA Heteromer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；277 K；FluB polymerase in a buffer containing 500 mM NaCl, 50 mM Hepes pH 7.5, 5% glycerol and 2mM Tris(2-carboxyethyl)phosphine (TCEP) was mixed with 5' and 3' ends of vRNA promoter and CTD peptide. Reservoir solution contained 0.1 M bicine pH 9.0, 10% MPD.
Resolution 3.50 Å R-free 0.268
5MSG Influenza B polymerase bound to vRNA promoter and capped RNA primer Deposited 2017-01-04 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded PO4 PHOSPHATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4；277 K；35 microM of FluB polymerase was mixed with 40 microM of the vRNA promoter and 40 microM 13-mer capped RNA primer in a buffer containing 500 mM NaCl, 50 mM HEPES pH 7.5, 5% glycerol and 2 mM TCEP. The best diffracting crystals appeared in 100 mM sodium acetate pH 3.8 - 4.0 and 150 mM di-ammonium phosphate
Resolution 3.80 Å R-free 0.267
6F5O A mechanism for the activation of the influenza virus transcriptase Deposited 2017-12-02 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: pentameric（5） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 9.80 Å
6FS8 Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA) Deposited 2018-02-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–197（197 aa）
Not recorded E4Z Baloxavir acid × 1 MN MANGANESE (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；Protein, at 15-17 mg/ml, was incubated with 10-fold molar excess of BXA for 30 min at RT, mixtures were centrifuged at RT for 5 minutes at 12000 g, and soluble fraction was used for crystallization trials (final protein concentration 8-10 mg/ml). Mother liquor was 0.2 M NaCl, 0.1 M Na(CH3)2AsO2 pH 6.5, 2 M (NH4)2SO4
Resolution 1.80 Å R-free 0.215
6FS8 Influenza B/Memphis/13/03 endonuclease with bound inhibitor, baloxavir acid (BXA) Deposited 2018-02-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–197（197 aa）
Not recorded E4Z Baloxavir acid × 1 MN MANGANESE (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；293 K；Protein, at 15-17 mg/ml, was incubated with 10-fold molar excess of BXA for 30 min at RT, mixtures were centrifuged at RT for 5 minutes at 12000 g, and soluble fraction was used for crystallization trials (final protein concentration 8-10 mg/ml). Mother liquor was 0.2 M NaCl, 0.1 M Na(CH3)2AsO2 pH 6.5, 2 M (NH4)2SO4
Resolution 1.80 Å R-free 0.215
6FS9 Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA) Deposited 2018-02-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–197（197 aa）
Mutation：I38T MN MANGANESE (II) ION × 2 E4Z Baloxavir acid × 1 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Protein, at 15-17 mg/ml, was incubated with 10-fold molar excess of BXA for 30 min at RT, mixtures were centrifuged at RT for 5 minutes at 12000 g, and soluble fraction was used for crystallization trials (final protein concentration 8-10 mg/ml). Mother liquor was 0.2 M CaCl2, 0.1 M MES pH 6.0, 20% (w/v) PEG6000
Resolution 2.28 Å R-free 0.235
6FSB Influenza B/Memphis/13/03 endonuclease with I38T mutation Deposited 2018-02-19 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 1–197（197 aa）
Mutation：I38T MN MANGANESE (II) ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Protein, at 15-17 mg/ml, was incubated with 10-fold molar excess of BXA for 30 min at RT, mixtures were centrifuged at RT for 5 minutes at 12000 g, and soluble fraction was used for crystallization trials (final protein concentration 8-10 mg/ml). Mother liquor was
Resolution 1.80 Å R-free 0.236
6FSB Influenza B/Memphis/13/03 endonuclease with I38T mutation Deposited 2018-02-19 Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 1–197（197 aa）
Mutation：I38T MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Protein, at 15-17 mg/ml, was incubated with 10-fold molar excess of BXA for 30 min at RT, mixtures were centrifuged at RT for 5 minutes at 12000 g, and soluble fraction was used for crystallization trials (final protein concentration 8-10 mg/ml). Mother liquor was
Resolution 1.80 Å R-free 0.236
6QCS Influenza B polymerase pre-initiation complex Deposited 2018-12-30 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.10 Å
6QCT Influenza B polymerase elongation complex Deposited 2018-12-30 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å
6QCV Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer and CTP Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded PO4 PHOSPHATE ION × 1 CTP CYTIDINE-5'-TRIPHOSPHATE × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；277 K；Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 14-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4. CTP was soaked for 18 hours into grown crystals at a final concentration of 5 mM in the drop.
Resolution 3.24 Å R-free 0.234
6QCW Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded PO4 PHOSPHATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；277 K；Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 14-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4.
Resolution 2.88 Å R-free 0.234
6QCX Crystal structure of influenza B polymerase initiation state with capped 15-mer RNA primer Deposited 2018-12-31 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded PO4 PHOSPHATE ION × 1 POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；277 K；Influenza B polymerase at 9 mg per ml in was mixed with 40 microM vRNA 5 prime end 14-mer, 40 microM vRNA 3 prime end 21-mer and 80 microM 15-mer capped RNA. The mother liquor contained 200 mM di-ammonium phosphate and 100 mM sodium acetate between pH 4.0 and 4.4.
Resolution 3.08 Å R-free 0.226
6T0W Human Influenza B polymerase recycling complex Deposited 2019-10-03 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.18 Å
7R1F Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106 Deposited 2022-02-02 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 3 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.58 Å
7Z42 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B Deposited 2022-03-03 Assembly 1 Protein–RNA Heteromer；Protein × 5 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Mutation：K135A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；FluPolB PA mutant K135A at 9 mg per ml was mixed with 40 microM of nucleotides 1-13 vRNA 5prime end, 5-pAGUAGUAACAAGA-3, and 1.8 mM 28-mer CTD peptide, YSPTpSPS x 4 in a buffer containing 50 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 2 mM TCEP. Hanging drops for crystallization were set up at 20 C.
Resolution 2.42 Å R-free 0.257
7Z42 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B Deposited 2022-03-03 Assembly 2 Protein–RNA Heteromer；Protein × 5 PDB declaration: hexameric（6） Consistent with all polymers
Chain D 1–726（726 aa）
Mutation：K135A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；FluPolB PA mutant K135A at 9 mg per ml was mixed with 40 microM of nucleotides 1-13 vRNA 5prime end, 5-pAGUAGUAACAAGA-3, and 1.8 mM 28-mer CTD peptide, YSPTpSPS x 4 in a buffer containing 50 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 2 mM TCEP. Hanging drops for crystallization were set up at 20 C.
Resolution 2.42 Å R-free 0.257
7Z43 Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B Deposited 2022-03-03 Assembly 1 Protein–RNA Heteromer；Protein × 5 PDB declaration: octameric（8） Consistent with all polymers
Chain AAA 1–726（726 aa）
Not recorded PO4 PHOSPHATE ION × 1 IC5 [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.4；277 K；200 mM di-ammonium phosphate, and 100 mM sodium acetate at pH 4.4
Resolution 3.12 Å R-free 0.272
8BDR Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position Deposited 2022-10-19 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 2 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
8BE0 Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position Deposited 2022-10-20 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 2 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.34 Å
8BF5 Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue Deposited 2022-10-24 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 3 G2P PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 GTA P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.96 Å
8RN1 Influenza B polymerase, monomeric encapsidase with 5' cRNA hook bound Deposited 2024-01-09 Assembly 1 Protein–RNA Heteromer；Protein × 3 PDB declaration: tetrameric（4） Consistent with all polymers
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.64 Å
8RN2 Monomeric apo-influenza B polymerase, encapsidase conformation Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.89 Å
8RN3 Pseudo-symmetrical influenza B polymerase apo-dimer, encapsidase moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–726（726 aa）
Chain D 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 3 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.78 Å
8RN4 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(T) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–726（726 aa）
Chain D 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.87 Å
8RN5 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(R) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–726（726 aa）
Chain E 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.88 Å
8RN6 Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(E) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.82 Å
8RN7 Pseudo-symmetrical influenza B polymerase apo-dimer, core-only moeity (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–726（726 aa）
Chain E 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.09 Å
8RN8 Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S)) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 1–726（726 aa）
Chain D 1–726（726 aa）
Not recorded MG MAGNESIUM ION × 5 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.92 Å
8RN9 Influenza B polymerase, replicase (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain A 1–726（726 aa）
Chain E 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.31 Å
8RNA Influenza B polymerase apo-trimer Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 10 PDB declaration: decameric（10） Consistent with protein count
Chain A 1–726（726 aa）
Chain D 1–726（726 aa）
Chain X 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.57 Å
8RNB Influenza B polymerase, encapsidase plus 627(R) / human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain D 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.31 Å
8RNC Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) Deposited 2024-01-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric（9） Consistent with protein count
Chain A 1–726（726 aa）
Chain D 1–726（726 aa）
Chain X 1–726（726 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.52 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.