Current Protein Identity:Q6ZMJ4 New Search
Main Difference Dimensions in This Set
Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
4DKC Crystal Structure of Human Interleukin-34 Deposited 2012-02-03 Assembly 1 Other combination Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 21–193(173 aa)
Chain B 21–193(173 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.1 M Hepes pH 7.5, 10% w/v Polyethylene glycol 6,000, 5% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 1.85 Å R-free 0.203
4DKD Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R Deposited 2012-02-03 Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain A 21–193(173 aa) Fragment:active core, UNP residues 21-193
Chain B 21–193(173 aa) Fragment:active core, UNP residues 21-193
Not recorded BMA beta-D-mannopyranose × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6;293 K;0.1M Calcium acetate, 0.1M Mes pH 6.0, 15% PEG 400, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 3.00 Å R-free 0.287
4DKE Crystal Structure of Human Interleukin-34 Bound to FAb1.1 Deposited 2012-02-03 Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 21–193(173 aa) Fragment:active core
Chain B 21–193(173 aa) Fragment:active core
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;0.2 M Ammonium phosphate monobasic, 0.1 M Tris pH 8.5, 50% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 3.00 Å R-free 0.265
4DKE Crystal Structure of Human Interleukin-34 Bound to FAb1.1 Deposited 2012-02-03 Assembly 2 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 21–193(173 aa) Fragment:active core
Chain B 21–193(173 aa) Fragment:active core
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;0.2 M Ammonium phosphate monobasic, 0.1 M Tris pH 8.5, 50% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 3.00 Å R-free 0.265
4DKF Crystal Structure of Human Interleukin-34 Bound to FAb2 Deposited 2012-02-03 Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count
Chain A 21–193(173 aa) Fragment:active core
Chain B 21–193(173 aa) Fragment:active core
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.2 M Potassium sodium tartrate tetrahydrate, 20% w/v Polyethylene glycol 3,350, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.61 Å R-free 0.256
4DKF Crystal Structure of Human Interleukin-34 Bound to FAb2 Deposited 2012-02-03 Assembly 2 Other combination Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count
Chain A 21–193(173 aa) Fragment:active core
Chain B 21–193(173 aa) Fragment:active core
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.2 M Potassium sodium tartrate tetrahydrate, 20% w/v Polyethylene glycol 3,350, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
Resolution 2.61 Å R-free 0.256