Current Protein Identity:Q6ZMJ4
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4DKC Crystal Structure of Human Interleukin-34 Deposited 2012-02-03 | Assembly 1 Other combination Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
21–193(173 aa)
Chain B
21–193(173 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.1 M Hepes pH 7.5, 10% w/v Polyethylene glycol 6,000, 5% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.85 Å R-free 0.203 |
| 4DKD Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R Deposited 2012-02-03 | Assembly 1 Other combination Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
21–193(173 aa)
Fragment:active core, UNP residues 21-193
Chain B
21–193(173 aa)
Fragment:active core, UNP residues 21-193
|
Not recorded | BMA beta-D-mannopyranose × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6;293 K;0.1M Calcium acetate, 0.1M Mes pH 6.0, 15% PEG 400, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 3.00 Å R-free 0.287 |
| 4DKE Crystal Structure of Human Interleukin-34 Bound to FAb1.1 Deposited 2012-02-03 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
21–193(173 aa)
Fragment:active core
Chain B
21–193(173 aa)
Fragment:active core
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;0.2 M Ammonium phosphate monobasic, 0.1 M Tris pH 8.5, 50% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 3.00 Å R-free 0.265 |
| 4DKE Crystal Structure of Human Interleukin-34 Bound to FAb1.1 Deposited 2012-02-03 | Assembly 2 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
21–193(173 aa)
Fragment:active core
Chain B
21–193(173 aa)
Fragment:active core
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 8.5;293 K;0.2 M Ammonium phosphate monobasic, 0.1 M Tris pH 8.5, 50% v/v (+/-)-2-Methyl-2,4-pentanediol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 3.00 Å R-free 0.265 |
| 4DKF Crystal Structure of Human Interleukin-34 Bound to FAb2 Deposited 2012-02-03 | Assembly 1 Other combination Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
21–193(173 aa)
Fragment:active core
Chain B
21–193(173 aa)
Fragment:active core
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.2 M Potassium sodium tartrate tetrahydrate, 20% w/v Polyethylene glycol 3,350, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.61 Å R-free 0.256 |
| 4DKF Crystal Structure of Human Interleukin-34 Bound to FAb2 Deposited 2012-02-03 | Assembly 2 Other combination Heteromer;Protein × 12 PDB declaration: dodecameric(12) Consistent with protein count |
Chain A
21–193(173 aa)
Fragment:active core
Chain B
21–193(173 aa)
Fragment:active core
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;293 K;0.2 M Potassium sodium tartrate tetrahydrate, 20% w/v Polyethylene glycol 3,350, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.61 Å R-free 0.256 |