Current Protein Identity：Q73QH2
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 10QF Crystal Structure of Treponema denticola Sialidase (TDE_0471) Deposited 2026-02-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
25–543（519 aa）
|
Not recorded | CD CADMIUM ION × 14 NA SODIUM ION × 2 B3P 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 CIT CITRIC ACID × 1 EDO 1,2-ETHANEDIOL × 14 PGE TRIETHYLENE GLYCOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.4；296 K；25 mM Citric acid, 75 mM Bis-tris propane, pH 7.4, 20 mM Cadmium chloride, 25% PEG400, seeded
|
Resolution 1.63 Å R-free 0.187 |
| 10QG Crystal Structure of Treponema denticola Sialidase (TDE_0471) bound to Neu5Ac2en (DANA) Deposited 2026-02-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
25–543（519 aa）
|
Not recorded | DAN 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID × 2 EDO 1,2-ETHANEDIOL × 5 PEG DI(HYDROXYETHYL)ETHER × 2 CD CADMIUM ION × 23 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.8；296 K；100 mM HEPES, pH 7.8, 20 mM Cadmium chloride, 25% PEG400, soak in mother liquor with 25 mM DANA for 20 min
|
Resolution 1.55 Å R-free 0.153 |
| 10QH Crystal Structure of Treponema denticola Sialidase (TDE_0471) Bound to Neu5Ac (NANA) Deposited 2026-02-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
25–543（519 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CD CADMIUM ION × 17 SLB N-acetyl-beta-neuraminic acid × 1 EDO 1,2-ETHANEDIOL × 9 PEG DI(HYDROXYETHYL)ETHER × 1 PGE TRIETHYLENE GLYCOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.2；296 K；100 mM Tris, pH 8.2, 20 mM Cadmium chloride, 25% PEG400, soak in mother liquor with 15 mM Neu5Ac
|
Resolution 1.56 Å R-free 0.158 |
| 10QI Crystal Structure of Treponema denticola Sialidase (TDE_0471) D165A mutant bound to 3'-sialyllactose (only Neu5Ac visible) Deposited 2026-02-01 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
25–543（519 aa）
|
Mutation：D165A | SIA N-acetyl-alpha-neuraminic acid × 1 GOL GLYCEROL × 4 PEG DI(HYDROXYETHYL)ETHER × 1 CD CADMIUM ION × 6 NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6.5；296 K；100 mM Bis-tris, pH 6.5, 20 mM Cadmium chliride, 23% PEG400, 5 mM 3'-sialyllactose
|
Resolution 1.81 Å R-free 0.190 |