Current Protein Identity:Q86WV5
New Search
Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4JOI Crystal structure of the human telomeric Stn1-Ten1 complex Deposited 2013-03-18 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
1–122(122 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4;291 K;0.8 M AmSO4, 0.1 M citric acid pH 4.0 and 5% jeffamine M-600, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.05 Å R-free 0.249 |
| 4JOI Crystal structure of the human telomeric Stn1-Ten1 complex Deposited 2013-03-18 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
1–122(122 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 4;291 K;0.8 M AmSO4, 0.1 M citric acid pH 4.0 and 5% jeffamine M-600, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.05 Å R-free 0.249 |
| 6W6W Cryo-EM structure of CST bound to telomeric single-stranded DNA Deposited 2020-03-17 | Assembly 1 Protein–DNA Heteromer;Protein × 4 PDB declaration: pentameric(5) Consistent with all polymers |
Chain D
3–123(121 aa)
|
Not recorded | ZN ZINC ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å |
| 7U5C Cryo-EM structure of human CST bound to DNA polymerase alpha-primase in a recruitment state Deposited 2022-03-02 | Assembly 1 Protein–DNA Heteromer;Protein × 7 PDB declaration: octameric(8) Consistent with all polymers |
Chain G
1–123(123 aa)
|
Not recorded | ZN ZINC ION × 4 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.60 Å |
| 8D0B Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template Deposited 2022-05-26 | Assembly 1 Protein–DNA Heteromer;Protein × 7 PDB declaration: octameric(8) Consistent with all polymers |
Chain C
3–123(121 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5;CHAPSO is only added just before sample vitrification.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.43 Å |
| 8D0K Human CST-DNA polymerase alpha/primase preinitiation complex bound to 4xTEL-foldback template - PRIM2C advanced PIC Deposited 2022-05-26 | Assembly 1 Protein–DNA Heteromer;Protein × 7 PDB declaration: octameric(8) Consistent with all polymers |
Chain C
3–123(121 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5;CHAPSO is only added just before sample vitrification.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.27 Å |
| 8SOJ Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA Deposited 2023-04-28 | Assembly 1 Insufficient information Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain C
1–123(123 aa)
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å |
| 8SOK Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the presence of telomeric ssDNA Deposited 2023-04-28 | Assembly 1 Insufficient information Heteromer;Protein × 5 PDB declaration: hexameric(6) Consistent with all polymers |
Chain C
1–123(123 aa)
|
Not recorded | ZN ZINC ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å |