Current Protein Identity:Q8WVM7
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 5QSM PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z57261895 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | O2D 2-cyclohexyl-N-(4H-1,2,4-triazol-4-yl)acetamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.74 Å R-free 0.299 |
| 5QSM PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z57261895 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.74 Å R-free 0.299 |
| 5QSN PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1272480091 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.66 Å R-free 0.288 |
| 5QSN PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1272480091 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | O2J (2R)-2-(methoxymethyl)-4-(pyridin-2-yl)morpholine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.66 Å R-free 0.288 |
| 5QSO PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z466628048 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | O2M N-[(4-methyl-1,3-thiazol-2-yl)methyl]-1H-pyrazole-5-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.70 Å R-free 0.295 |
| 5QSO PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z466628048 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.70 Å R-free 0.295 |
| 5QSP PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | LVV 4-[(4-methylphenyl)methyl]-1,4-thiazinane 1,1-dioxide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.89 Å R-free 0.263 |
| 5QSP PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.89 Å R-free 0.263 |
| 5QSQ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | HR5 ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.48 Å R-free 0.289 |
| 5QSQ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | HR5 ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.48 Å R-free 0.289 |
| 5QSR PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | NU4 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.28 Å R-free 0.294 |
| 5QSR PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | NU4 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.28 Å R-free 0.294 |
| 5QSS PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z33452282 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | O2P N-(2-hydroxy-4-methylphenyl)-2-methylbenzamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.08 Å R-free 0.296 |
| 5QSS PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z33452282 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.08 Å R-free 0.296 |
| 5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | O3A (3S)-N-methyl-N-phenylpyrrolidine-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.58 Å R-free 0.271 |
| 5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.58 Å R-free 0.271 |
| 5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.58 Å R-free 0.271 |
| 5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.58 Å R-free 0.271 |
| 5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | O3D 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.73 Å R-free 0.263 |
| 5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.73 Å R-free 0.263 |
| 5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.73 Å R-free 0.263 |
| 5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.73 Å R-free 0.263 |
| 5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.76 Å R-free 0.264 |
| 5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.76 Å R-free 0.264 |
| 5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.76 Å R-free 0.264 |
| 5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | O3G N-benzyl-1-(4-fluorophenyl)methanamine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.76 Å R-free 0.264 |
| 5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.03 Å R-free 0.267 |
| 5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.03 Å R-free 0.267 |
| 5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.03 Å R-free 0.267 |
| 5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.03 Å R-free 0.267 |
| 5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.34 Å R-free 0.275 |
| 5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.34 Å R-free 0.275 |
| 5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.34 Å R-free 0.275 |
| 5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.34 Å R-free 0.275 |
| 5QSY PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z755044716 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.40 Å R-free 0.297 |
| 5QSY PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z755044716 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | K0J N-ethyl-1H-1,2,3-triazole-4-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.40 Å R-free 0.297 |
| 5QSZ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1267773786 Deposited 2019-05-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | K3J N-ethyl-6-methylpyridazin-3-amine × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.08 Å R-free 0.292 |
| 5QSZ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1267773786 Deposited 2019-05-25 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 3.08 Å R-free 0.292 |
| 6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
|
Resolution 2.02 Å R-free 0.245 |
| 6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
|
Resolution 2.02 Å R-free 0.245 |
| 6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 | Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
|
Resolution 2.02 Å R-free 0.245 |
| 6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 | Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain D
86–420(335 aa)
|
Not recorded | NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
|
Resolution 2.02 Å R-free 0.245 |
| 6R7O Crystal structure of the central region of human cohesin subunit STAG1 Deposited 2019-03-29 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;277 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.31 Å R-free 0.264 |
| 6R7O Crystal structure of the central region of human cohesin subunit STAG1 Deposited 2019-03-29 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;277 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
|
Resolution 2.31 Å R-free 0.264 |
| 6RRC Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-17 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
86–420(335 aa)
|
Not recorded | SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.3;277 K;2.1 M Ammonium Sulfate, 0.1 M MES pH 6.3
|
Resolution 2.37 Å R-free 0.248 |
| 6RRC Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-17 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
86–420(335 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6.3;277 K;2.1 M Ammonium Sulfate, 0.1 M MES pH 6.3
|
Resolution 2.37 Å R-free 0.248 |
| 6RRK Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-20 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;16 % PEG 3350, 0.2 M DL-Mallic acid
|
Resolution 3.17 Å R-free 0.278 |
| 6RRK Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-20 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
459–915(457 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;277 K;16 % PEG 3350, 0.2 M DL-Mallic acid
|
Resolution 3.17 Å R-free 0.278 |
| 6WG3 Cryo-EM structure of human Cohesin-NIPBL-DNA complex Deposited 2020-04-04 | Assembly 1 Protein–DNA Heteromer;Protein × 5 PDB declaration: heptameric(7) Consistent with all polymers |
Chain D
1–1258(1258 aa)
|
Not recorded | ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 5.30 Å |
| 7W1M Cryo-EM structure of human cohesin-CTCF-DNA complex Deposited 2021-11-19 | Assembly 1 Protein–DNA Heteromer;Protein × 6 PDB declaration: octameric(8) Consistent with all polymers |
Chain D
1–1258(1258 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 2 BEF BERYLLIUM TRIFLUORIDE ION × 2 ZN ZINC ION × 11 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 6.50 Å |