Current Protein Identity:Q8WVM7 New Search
Main Difference Dimensions in This Set
Different construct Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
5QSM PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z57261895 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded O2D 2-cyclohexyl-N-(4H-1,2,4-triazol-4-yl)acetamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.74 Å R-free 0.299
5QSM PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z57261895 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.74 Å R-free 0.299
5QSN PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1272480091 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.66 Å R-free 0.288
5QSN PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1272480091 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded O2J (2R)-2-(methoxymethyl)-4-(pyridin-2-yl)morpholine × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.66 Å R-free 0.288
5QSO PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z466628048 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded O2M N-[(4-methyl-1,3-thiazol-2-yl)methyl]-1H-pyrazole-5-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.70 Å R-free 0.295
5QSO PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z466628048 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.70 Å R-free 0.295
5QSP PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded LVV 4-[(4-methylphenyl)methyl]-1,4-thiazinane 1,1-dioxide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.89 Å R-free 0.263
5QSP PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434929 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.89 Å R-free 0.263
5QSQ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded HR5 ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.48 Å R-free 0.289
5QSQ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded HR5 ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.48 Å R-free 0.289
5QSR PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded NU4 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.28 Å R-free 0.294
5QSR PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z136583524 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded NU4 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.28 Å R-free 0.294
5QSS PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z33452282 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded O2P N-(2-hydroxy-4-methylphenyl)-2-methylbenzamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.08 Å R-free 0.296
5QSS PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z33452282 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.08 Å R-free 0.296
5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded O3A (3S)-N-methyl-N-phenylpyrrolidine-3-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.58 Å R-free 0.271
5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.58 Å R-free 0.271
5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.58 Å R-free 0.271
5QST PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438 Deposited 2019-05-25 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.58 Å R-free 0.271
5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded O3D 4-[(furan-2-yl)methyl]-1lambda~6~,4-thiazinane-1,1-dione × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.73 Å R-free 0.263
5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.73 Å R-free 0.263
5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.73 Å R-free 0.263
5QSU PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434926 Deposited 2019-05-25 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.73 Å R-free 0.263
5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.76 Å R-free 0.264
5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.76 Å R-free 0.264
5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.76 Å R-free 0.264
5QSV PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434783 Deposited 2019-05-25 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded O3G N-benzyl-1-(4-fluorophenyl)methanamine × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.76 Å R-free 0.264
5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.03 Å R-free 0.267
5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.03 Å R-free 0.267
5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.03 Å R-free 0.267
5QSW PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434884 Deposited 2019-05-25 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded O3J 1-[4-(3-phenylpropyl)piperazin-1-yl]ethan-1-one × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.03 Å R-free 0.267
5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.34 Å R-free 0.275
5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.34 Å R-free 0.275
5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.34 Å R-free 0.275
5QSX PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2856434812 Deposited 2019-07-16 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded O3M 4-[(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenol × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.34 Å R-free 0.275
5QSY PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z755044716 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.40 Å R-free 0.297
5QSY PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z755044716 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded K0J N-ethyl-1H-1,2,3-triazole-4-carboxamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.40 Å R-free 0.297
5QSZ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1267773786 Deposited 2019-05-25 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded K3J N-ethyl-6-methylpyridazin-3-amine × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.08 Å R-free 0.292
5QSZ PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z1267773786 Deposited 2019-05-25 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;298 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 3.08 Å R-free 0.292
6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
Resolution 2.02 Å R-free 0.245
6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
Resolution 2.02 Å R-free 0.245
6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 Assembly 3 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
Resolution 2.02 Å R-free 0.245
6QB5 Crystal structure of the N-terminal region of human cohesin subunit STAG1 Deposited 2018-12-20 Assembly 4 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain D 86–420(335 aa)
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;0.1 M Na/K Phosphate pH 6.0, 0.2 M NaCl, 34% PEG200
Resolution 2.02 Å R-free 0.245
6R7O Crystal structure of the central region of human cohesin subunit STAG1 Deposited 2019-03-29 Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;277 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.31 Å R-free 0.264
6R7O Crystal structure of the central region of human cohesin subunit STAG1 Deposited 2019-03-29 Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7;277 K;0.1 M Bis Tris Propane pH 7.0, 0.2 M Sodium Malonate, 20 % PEG 3350, 10 % Ethylene Glycol
Resolution 2.31 Å R-free 0.264
6RRC Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-17 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain C 86–420(335 aa)
Not recorded SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.3;277 K;2.1 M Ammonium Sulfate, 0.1 M MES pH 6.3
Resolution 2.37 Å R-free 0.248
6RRC Crystal structure of the N-terminal region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-17 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 86–420(335 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 6.3;277 K;2.1 M Ammonium Sulfate, 0.1 M MES pH 6.3
Resolution 2.37 Å R-free 0.248
6RRK Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-20 Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain B 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;16 % PEG 3350, 0.2 M DL-Mallic acid
Resolution 3.17 Å R-free 0.278
6RRK Crystal structure of the central region of human cohesin subunit STAG1 in complex with RAD21 peptide Deposited 2019-05-20 Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count
Chain A 459–915(457 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;277 K;16 % PEG 3350, 0.2 M DL-Mallic acid
Resolution 3.17 Å R-free 0.278
6WG3 Cryo-EM structure of human Cohesin-NIPBL-DNA complex Deposited 2020-04-04 Assembly 1 Protein–DNA Heteromer;Protein × 5 PDB declaration: heptameric(7) Consistent with all polymers
Chain D 1–1258(1258 aa)
Not recorded ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 5.30 Å
7W1M Cryo-EM structure of human cohesin-CTCF-DNA complex Deposited 2021-11-19 Assembly 1 Protein–DNA Heteromer;Protein × 6 PDB declaration: octameric(8) Consistent with all polymers
Chain D 1–1258(1258 aa)
Not recorded ADP ADENOSINE-5'-DIPHOSPHATE × 2 BEF BERYLLIUM TRIFLUORIDE ION × 2 ZN ZINC ION × 11 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 6.50 Å