Current Protein Identity：Q99497
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1J42 Crystal Structure of Human DJ-1 Deposited 2003-02-26 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6.5；295 K；sodium acetate, EVAPORATION, temperature 295K, pH 4-9, pH 6.5
|
Resolution 2.50 Å R-free 0.249 |
| 1J42 Crystal Structure of Human DJ-1 Deposited 2003-02-26 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6.5；295 K；sodium acetate, EVAPORATION, temperature 295K, pH 4-9, pH 6.5
|
Resolution 2.50 Å R-free 0.249 |
| 1P5F Crystal Structure of Human DJ-1 Deposited 2003-04-26 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；296 K；PEG 400, tris-HCl, sodium citrate, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 23K
|
Resolution 1.10 Å R-free 0.161 |
| 1P5F Crystal Structure of Human DJ-1 Deposited 2003-04-26 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；296 K；PEG 400, tris-HCl, sodium citrate, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 23K
|
Resolution 1.10 Å R-free 0.161 |
| 1PDV Crystal structure of human DJ-1, P 31 2 1 space group Deposited 2003-05-20 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；10% PEG3350, 100 mM Tris, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.80 Å R-free 0.215 |
| 1PDW Crystal structure of human DJ-1, P 1 21 1 space group Deposited 2003-05-20 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；10% PEG3350, 100 mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.243 |
| 1PDW Crystal structure of human DJ-1, P 1 21 1 space group Deposited 2003-05-20 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1–189（189 aa）
Chain D
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；10% PEG3350, 100 mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.243 |
| 1PDW Crystal structure of human DJ-1, P 1 21 1 space group Deposited 2003-05-20 | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain E
1–189（189 aa）
Chain F
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；10% PEG3350, 100 mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.243 |
| 1PDW Crystal structure of human DJ-1, P 1 21 1 space group Deposited 2003-05-20 | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain G
1–189（189 aa）
Chain H
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；277 K；10% PEG3350, 100 mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.20 Å R-free 0.243 |
| 1PE0 Crystal structure of the K130R mutant of human DJ-1 Deposited 2003-05-20 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Mutation：K130R Mutation：K130R | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；20% PEG3350, 100 mM Bis-tris(7.0), 50 mM CaCl2, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.70 Å R-free 0.231 |
| 1Q2U Crystal structure of DJ-1/RS and implication on familial Parkinson's disease Deposited 2003-07-26 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；12% PEG 3350, 0.1M Tris.base, 5% MPD, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.60 Å R-free 0.202 |
| 1Q2U Crystal structure of DJ-1/RS and implication on familial Parkinson's disease Deposited 2003-07-26 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；298 K；12% PEG 3350, 0.1M Tris.base, 5% MPD, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.60 Å R-free 0.202 |
| 1SOA Human DJ-1 with sulfinic acid Deposited 2004-03-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；peg 400, sodium citrate, tris-HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.20 Å R-free 0.141 |
| 1UCF The Crystal Structure of DJ-1, a Protein Related to Male Fertility and Parkinson's Disease Deposited 2003-04-11 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；sodium citrate, HEPES, DTT, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.95 Å R-free 0.195 |
| 2OR3 Pre-oxidation Complex of Human DJ-1 Deposited 2007-02-01 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；28% PEG 4000, 200 mM ammonium sulfate, 50 mM sodium acetate, 2.5 mM epigallocatechin 3-gallate, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.20 Å R-free 0.182 |
| 2R1T dopamine quinone conjugation to DJ-1 Deposited 2007-08-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–188（187 aa）
Chain B
2–188（187 aa）
|
Mutation：C106A Mutation：C106A Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；290 K；29% PEG4K, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 290K
|
Resolution 1.70 Å R-free 0.236 |
| 2R1U DJ-1 activation by catechol quinone modification Deposited 2007-08-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–188（187 aa）
Chain B
2–188（187 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；290 K；29%PEG4K, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 290K
|
Resolution 1.50 Å R-free 0.195 |
| 2R1V Norepinephrine quinone conjugation to DJ-1 Deposited 2007-08-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–188（187 aa）
Chain B
2–188（187 aa）
|
Mutation：C106A Mutation：C106A Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；290 K；29% PEG4K, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 290K
|
Resolution 1.70 Å R-free 0.202 |
| 2RK3 Structure of A104T DJ-1 Deposited 2007-10-16 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：A104T | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；30% PEG 3000, 100 mM HEPES, 200 mM NaCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.05 Å R-free 0.150 |
| 2RK4 Structure of M26I DJ-1 Deposited 2007-10-16 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：M26I | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；30% PEG 3000, 100 mM HEPES, 200 mM NaCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.15 Å R-free 0.156 |
| 2RK6 Structure of E163K DJ-1 Deposited 2007-10-16 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E163K Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.5 M sodium citrate, 20 mM HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.15 Å R-free 0.175 |
| 3B36 Structure of M26L DJ-1 Deposited 2007-10-19 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：M26I | CL CHLORIDE ION × 2 EDO 1,2-ETHANEDIOL × 16 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；298 K；30% PEG 3000, 100 mM HEPES, 200 mM NaCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K, pH 7.50
|
Resolution 1.50 Å R-free 0.175 |
| 3B38 Structure of A104V DJ-1 Deposited 2007-10-19 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：A104V | EDO 1,2-ETHANEDIOL × 14 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；30% PEG 3000, 100 mM HEPES, 200 mM NaCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.85 Å R-free 0.226 |
| 3B3A Structure of E163K/R145E DJ-1 Deposited 2007-10-19 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E163K/R145E | CL CHLORIDE ION × 2 EDO 1,2-ETHANEDIOL × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；30% PEG 3000, 100 mM HEPES, 200 mM NaCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.203 |
| 3BWE Crystal structure of aggregated form of DJ1 Deposited 2008-01-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；EVAPORATION
|
Resolution 2.40 Å R-free 0.282 |
| 3BWE Crystal structure of aggregated form of DJ1 Deposited 2008-01-09 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1–189（189 aa）
Chain D
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；EVAPORATION
|
Resolution 2.40 Å R-free 0.282 |
| 3BWE Crystal structure of aggregated form of DJ1 Deposited 2008-01-09 | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain E
1–189（189 aa）
Chain F
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) | PO4 PHOSPHATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；EVAPORATION
|
Resolution 2.40 Å R-free 0.282 |
| 3BWE Crystal structure of aggregated form of DJ1 Deposited 2008-01-09 | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain G
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；EVAPORATION
|
Resolution 2.40 Å R-free 0.282 |
| 3CY6 Crystal Structure of E18Q DJ-1 Deposited 2008-04-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18Q | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.5 M sodium citrate, 50 mM HEPES, 10 mM DTT, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.35 Å R-free 0.168 |
| 3CYF Crystal Structure of E18N DJ-1 Deposited 2008-04-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18N Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；298 K；1.6 M sodium citrate, 50 mM HEPES, 10 mM DTT, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.60 Å R-free 0.184 |
| 3CZ9 Crystal Structure of E18L DJ-1 Deposited 2008-04-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18L | P4C O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.5 M sodium citrate, 50 mM HEPES, 10 mM DTT, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.15 Å R-free 0.140 |
| 3CZA Crystal Structure of E18D DJ-1 Deposited 2008-04-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18D | MLA MALONIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.5 M sodium citrate, 50 mM HEPES, 10 mM DTT, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.20 Å R-free 0.164 |
| 3EZG Crystal structure of E18Q DJ-1 with oxidized C106 Deposited 2008-10-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18Q Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；298 K；30% PEG400, 50 mM HEPES, 125 mM sodium citrate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.15 Å R-free 0.145 |
| 3F71 Crystal structure of E18D DJ-1 with oxidized C106 Deposited 2008-11-07 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18D Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；1.5 M sodium citrate, 25 mM HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.20 Å R-free 0.155 |
| 3SF8 Structural insights into thiol stabilization of DJ-1 Deposited 2011-06-13 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
Chain B
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；293 K；45% (v/v) polyproylene glycol 400, 0.1 M Bis-Tris, pH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.56 Å R-free 0.211 |
| 4BTE DJ-1 Cu(I) complex Deposited 2013-06-14 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | CU1 COPPER (I) ION × 2 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 1.38 Å R-free 0.150 |
| 4MNT Crystal structure of human DJ-1 in complex with Cu Deposited 2013-09-11 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | CU COPPER (II) ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.2 M Sodium Malonate, 20% w/v PEG 3350, pH 8, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.58 Å R-free 0.177 |
| 4MTC Crystal structure of human C53A DJ-1 Deposited 2013-09-19 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：C53A | EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Sodium Malonate, 20% w/v PEG 3350, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.47 Å R-free 0.165 |
| 4N0M Crystal structure of human C53A DJ-1 in complex with Cu Deposited 2013-10-02 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：C53A | CU COPPER (II) ION × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；0.2 M Sodium Malonate, 20% w/v PEG 3350, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.95 Å R-free 0.175 |
| 4N12 Crystal structure of human E18D DJ-1 in complex with Cu Deposited 2013-10-03 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18D Non-standard monomer：Yes (specific site not provided by mmCIF) | CU COPPER (II) ION × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；0.2 M Sodium Malonate and 20% w/v PEG 3350, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.48 Å R-free 0.174 |
| 4OGF Crystal Structure of Human DJ-1 with glyoxylate as substrate analog Deposited 2014-01-16 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–188（187 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；0.1 M HEPES, 1.4 M sodium citrate, pH 7.5, VAPOR DIFFUSION, HANGING DROP
|
Resolution 1.60 Å R-free 0.235 |
| 4OQ4 Crystal Structure of E18A Human DJ-1 Deposited 2014-02-07 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E18A Non-standard monomer：Yes (specific site not provided by mmCIF) | NA SODIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；1.3-1.6 M sodium citrate, 50 mM HEPES, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 1.49 Å R-free 0.139 |
| 4P2G Crystal structure of DJ-1 in sulfinic acid form (aged crystal) Deposited 2014-03-04 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 1PE PENTAETHYLENE GLYCOL × 2 EDO 1,2-ETHANEDIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；200 mM sodium citrate
30% (v:v) PEG400
|
Resolution 1.35 Å R-free 0.120 |
| 4P34 Crystal structure of DJ-1 in sulfenic acid form (fresh crystal) Deposited 2014-03-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | 1PE PENTAETHYLENE GLYCOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；200 mM sodium citrate
30% (v:v) PEG-400
|
Resolution 1.55 Å R-free 0.151 |
| 4P35 Crystal structure of DJ-1 with Zinc(II) bound (crystal I) Deposited 2014-03-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | ZN ZINC ION × 2 CL CHLORIDE ION × 2 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；100 mM TRIS
20% (v:v) PEG-400
Co-crystal with 500 uM Zn(II)
|
Resolution 1.75 Å R-free 0.171 |
| 4P36 Crystal structure of DJ-1 With Zn(II) bound (crystal 2) Deposited 2014-03-05 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | P15 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL × 2 ZN ZINC ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293 K；200 mM Sodium citrate
30% (v:v) PEG-400
500 uM Zinc sulfate
|
Resolution 1.18 Å R-free 0.138 |
| 4RKW Crystal structure of DJ-1 Deposited 2014-10-14 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 4.6；298 K；28-32% PEG400, 100 mM citrate, pH 4.6, VAPOR DIFFUSION, temperature 298.0K
|
Resolution 1.50 Å R-free 0.153 |
| 4RKY Crystal structure of DJ-1 isoform X1 Deposited 2014-10-14 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 4.6；298 K；28-32% PEG400, 100 mM citrate, pH 4.6, VAPOR DIFFUSION, temperature 298K
|
Resolution 1.50 Å R-free 0.193 |
| 4S0Z Crystal structure of M26V human DJ-1 Deposited 2015-01-07 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：M26V | EDO 1,2-ETHANEDIOL × 8 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 9；298 K；100 mM Tris-HCl pH 9.0, 200 mM sodium acetate trihydrate, 25% PEG 4000 and 3 mM DTT, VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 1.45 Å R-free 0.132 |
| 4ZGG Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution Deposited 2015-04-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；277 K；5.00% polyethylene glycol 6000, 0.1M TRIS pH 8.0
|
Resolution 1.23 Å R-free 0.134 |
| 4ZGG Crystal structure of a DJ-1 (PARK7) from Homo sapiens at 1.23 A resolution Deposited 2015-04-22 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 20 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；277 K；5.00% polyethylene glycol 6000, 0.1M TRIS pH 8.0
|
Resolution 1.23 Å R-free 0.134 |
| 5IP5 Human DJ-1 complexed with Na-K-tartrate Deposited 2016-03-09 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | TLA L(+)-TARTARIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
MICROBATCH；pH 6.5；295 K；1.5 M sodium potassium tartrate, 3.5 M ammonium sulfate, 0.1 M Na-Cacodylate
|
Resolution 1.66 Å R-free 0.164 |
| 5SY6 Atomic resolution structure of human DJ-1, DTT bound Deposited 2016-08-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | DTT 2,3-DIHYDROXY-1,4-DITHIOBUTANE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；298 K；23-27% PEG 3000, 100 mM HEPES, 200 mM NaCl, 10 mM dithiothreitol (DTT)
|
Resolution 1.15 Å R-free 0.129 |
| 5SY9 Atomic resolution structure of E15Q mutant human DJ-1 Deposited 2016-08-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：E15Q Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；298 K；25-28% PEG 4000, 0.1 M Tris HCl, 0.1 M sodium citrate
|
Resolution 1.10 Å R-free 0.137 |
| 5SYA Atomic resolution structure of D24N mutant human DJ-1 Deposited 2016-08-10 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：D24N Non-standard monomer：Yes (specific site not provided by mmCIF) | EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.5；298 K；23-27% polyethylene glycol (PEG) 4000, 0.2 M Sodium Citrate, and 0.1 M Tris HCl
|
Resolution 1.10 Å R-free 0.128 |
| 6AF5 DJ-1 after backsoaking Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | ISN ISATIN × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.65 Å R-free 0.176 |
| 6AF7 DJ-1 C106S unbound Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：C106S | 1PE PENTAETHYLENE GLYCOL × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；pH 8.5, 100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.30 Å R-free 0.120 |
| 6AF9 DJ-1 with isatin bound (high concentration) Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | ISN ISATIN × 6 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.39 Å R-free 0.135 |
| 6AFA DJ-1 with isatin (low concentration) Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | ISN ISATIN × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.65 Å R-free 0.187 |
| 6AFB DJ-1 C106S incubated with isatin Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：C106S | ISN ISATIN × 4 CL CHLORIDE ION × 2 DMS DIMETHYL SULFOXIDE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG-400, 5mM DTT
|
Resolution 1.60 Å R-free 0.172 |
| 6AFC DJ-1 with compound 4 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 72R 5-fluoranyl-1~{H}-indole-2,3-dione × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG-400, 5mM DTT
|
Resolution 1.45 Å R-free 0.160 |
| 6AFD DJ-1 with compound 6 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 72S 7-methyl-1~{H}-indole-2,3-dione × 4 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG-400, 5mM DTT
|
Resolution 1.48 Å R-free 0.143 |
| 6AFE DJ-1 with compound 7 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 72T 7-(trifluoromethyl)-1~{H}-indole-2,3-dione × 4 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.50 Å R-free 0.146 |
| 6AFF DJ-1 with compound 8 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 72U methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate × 4 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.60 Å R-free 0.177 |
| 6AFG DJ-1 with compound 9 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 72V 1-methylindole-2,3-dione × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.50 Å R-free 0.148 |
| 6AFH DJ-1 with compound 10 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 73F 1-(2-phenylethyl)indole-2,3-dione × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.65 Å R-free 0.192 |
| 6AFI DJ-1 with compound 11 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 73D 1-ethylindole-2,3-dione × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.65 Å R-free 0.183 |
| 6AFJ DJ-1 with compound 13 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 73G butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.48 Å R-free 0.172 |
| 6AFL DJ-1 with compound 15 Deposited 2018-08-08 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 73H 5-fluoranyl-1-(2-phenylethyl)indole-2,3-dione × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；293.15 K；100mM TRIS-HCl, 200mM sodium citrate, 30% PEG 400, 5mM DTT
|
Resolution 1.60 Å R-free 0.174 |
| 6E5Z Crystal structure of human DJ-1 with a natural modification on Cys-106 Deposited 2018-07-23 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | CL CHLORIDE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；0.1M HEPES-Na, 1.5M Tri-sodium citrate dihydrate pH=7.5
|
Resolution 1.35 Å R-free 0.139 |
| 6M8Z Crystal structure of human DJ-1 without a modification on Cys-106 Deposited 2018-08-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 2 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；298 K；500 nL of protein in 50 mM Tris pH 8.0 and 500 mM NaCl were mixed with 500nL of 0.1M Bis-tris pH 5.5, 0.1M KSCN, and 29% PEG MME 2000
|
Resolution 1.83 Å R-free 0.204 |
| 7C62 The Crystal Structure of Parkinson disease protein 7 (DJ-1) from Biortus Deposited 2020-05-21 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；2.1 M DL-Malic acid pH 7.0
|
Resolution 2.03 Å R-free 0.174 |
| 7PA2 PARK7 with inhibitor 8RK64 Deposited 2021-07-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain AAA
1–189（189 aa）
|
Not recorded | 6SI (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 9；293 K；0.1 M Bicine pH 9.0
10% (w/v) PEG 20 000
2% (w/v) 1,4-dioxane
|
Resolution 1.21 Å R-free 0.155 |
| 7PA3 PARK7 with covalent inhibitor JYQ-88 Deposited 2021-07-28 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain AAA
1–189（189 aa）
|
Not recorded | 6SI (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；293 K；0.1 M Ammonium sulfate
0.1 M Bis-Tris pH 5.5
25% (w/v) PEG 3350
|
Resolution 1.42 Å R-free 0.214 |
| 8PPW Structure of human PARK7 in complex with GK16S Deposited 2023-07-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 86F (3~{S})-1-(iminomethyl)-~{N}-pent-4-ynyl-pyrrolidine-3-carboxamide × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；22.3% (v/v) PEG3350, 230 mM KNO3
|
Resolution 1.53 Å R-free 0.182 |
| 8PQ0 Structure of human PARK7 in complex with GK16R Deposited 2023-07-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 8RX (3~{R})-3-(pent-4-ynylcarbamoyl)pyrrolidine-1-carboximidothioic acid × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；18.6% (v/v) PEG3350, 170 mM NaNO3
|
Resolution 1.48 Å R-free 0.182 |
| 9CEI Human DJ-1, no mixing, pink beam time-resolved serial crystallography Deposited 2024-06-26 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.235 |
| 9CFI Human DJ-1, 3 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.235 |
| 9CFM Human DJ-1, 5 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.240 |
| 9CFO Human DJ-1, 10 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.231 |
| 9CFQ Human DJ-1, no mixing, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 1.90 Å R-free 0.169 |
| 9CFY Human DJ-1, 15 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.230 |
| 9CFZ Human DJ-1, 20 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.237 |
| 9CG0 Human DJ-1, 30 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350
|
Resolution 1.77 Å R-free 0.236 |
| 9CGA Human DJ-1, 3 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 2.01 Å R-free 0.178 |
| 9CGB Human DJ-1, 5 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 2.01 Å R-free 0.188 |
| 9CGD Human DJ-1, 10 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 1.97 Å R-free 0.177 |
| 9CGE Human DJ-1, 15 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 1.90 Å R-free 0.176 |
| 9CGF Human DJ-1, 20 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | 4Y8 1-hydroxypropan-2-one × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 2.06 Å R-free 0.190 |
| 9CGG Human DJ-1, 30 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography, CrystFEL processed Deposited 2024-06-28 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 2.01 Å R-free 0.182 |
| 9CMX Human DJ-1, fixed target serial crystallography Deposited 2024-07-15 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 1.63 Å R-free 0.168 |
| 9CMY Human DJ-1, 6.5-18.5 min mixing with methylglyoxal, fixed target serial crystallography Deposited 2024-07-15 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
BATCH MODE；pH 7.5；293 K；100 mM HEPES, 200 mM NaCl, 15% (w/v) PEG 3350
|
Resolution 1.69 Å R-free 0.175 |
| 9K7Q Parkinson disease protein 7 (DJ-1) and Alpha-synuclein (Alpha-syn) complex Deposited 2024-10-24 | Assembly 1 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count |
Chain A
2–188（187 aa）
Chain D
2–188（187 aa）
Chain E
2–188（187 aa）
Chain F
2–188（187 aa）
Chain H
2–188（187 aa）
Chain J
2–188（187 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；0.2 M Sodium iodide, 20% w/v Polyethylene glycol 3,350, pH 7.0
|
Resolution 4.58 Å R-free 0.222 |
| 9YCU Protiated human DJ-1, 100K Deposited 2025-09-19 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；22-24% PEG 3000, 200 mM NaCl, and 100 mM HEPES, pH 7.5
|
Resolution 1.05 Å R-free 0.134 |
| 9YFR perdeuterated human DJ-1, 100K Deposited 2025-09-26 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；295 K；22-24% PEG 3000, 200 mM NaCl, and 100 mM HEPES, pH 7.5
|
Resolution 0.92 Å R-free 0.113 |
| 9YGX I21T mutant human DJ-1 Deposited 2025-09-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：I21T | EDO 1,2-ETHANEDIOL × 10 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；22-27% PEG4000, 0.2 M sodium acetate, and 100 mM Tris HCl, pH=7.4
|
Resolution 0.97 Å R-free 0.113 |
| 9YH8 M17T Human DJ-1 Deposited 2025-09-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Mutation：M17T | EDO 1,2-ETHANEDIOL × 10 CL CHLORIDE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；19-22% PEG 4000, 200 mM MgCl2, and 100 mM Tris HCl, pH=8.5
|
Resolution 1.00 Å R-free 0.130 |
| 9YZV Joint Xray/Neutron structure of human DJ-1 at room temperature Deposited 2025-10-30 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–189（189 aa）
|
Not recorded | D8U deuterium(1+) × 2 | Not declared |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；289 K；20% PEG3350, 100 mM HEPES pH=7.5 and 200 mM KCl
|
Resolution not provided |