Current Protein Identity：Q9GZQ8
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1V49 Solution structure of microtubule-associated protein light chain-3 Deposited 2003-11-11 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
0–119（120 aa）
Fragment：residues 1-120
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 230；Pressure 1
NMR sample composition
0.8mM protein U-15N, 13C; 25mM phosphate buffer NA; 100mM NACL; 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.8mM protein U-15N, 13C; 25mM phosphate buffer NA; 100mM NACL; 100% D2O | 100% D2O
|
Resolution not provided |
| 2LUE LC3B OPTN-LIR Ptot complex structure Deposited 2012-06-13 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
5–119（115 aa）
Fragment：UNP RESIDUES 5-119
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.8；288 K；Ionic strength (raw mmCIF value) 0.05；Pressure ambient
NMR sample composition
0.6 mM [U-98% 13C; U-98% 15N] entity_1-1, 4.9 mM entity_2-2, 70 mM sodium phosphate-3, 30 mM sodium chloride-4, 0.3 mM DSS-5, 5 mM Protease inhibitors cocktail-6, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
2.5 mM [U-98% 13C; U-98% 15N] entity_1-7, 0.4 mM entity_2-8, 70 mM sodium phosphate-9, 30 mM sodium chloride-10, 0.3 mM DSS-11, 5 mM Protease inhibitors cocktail-12, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2N9X LC3 FUNDC1 complex structure Deposited 2015-12-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–120（120 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 0.15；Pressure ambient
NMR sample composition
0.9 mM [U-13C; U-15N] entity_1-1, 1.8 mM entity_2-2, 100 mM sodium chloride-3, 25 mM sodium phosphate-4, 10 % [U-2H] D2O-5, 1 % DSS-6, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2ZJD Crystal Structure of LC3-p62 complex Deposited 2008-03-05 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；288 K；0.1M HEPES pH 7.5, 23% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 288K
|
Resolution 1.56 Å R-free 0.238 |
| 2ZJD Crystal Structure of LC3-p62 complex Deposited 2008-03-05 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；288 K；0.1M HEPES pH 7.5, 23% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 288K
|
Resolution 1.56 Å R-free 0.238 |
| 2ZJD Crystal Structure of LC3-p62 complex Deposited 2008-03-05 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；288 K；0.1M HEPES pH 7.5, 23% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 288K
|
Resolution 1.56 Å R-free 0.238 |
| 2ZJD Crystal Structure of LC3-p62 complex Deposited 2008-03-05 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；288 K；0.1M HEPES pH 7.5, 23% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 288K
|
Resolution 1.56 Å R-free 0.238 |
| 3VTU Crystal structure of human LC3B_2-119 Deposited 2012-06-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP RESIDUES 2-119
|
Not recorded | SO4 SULFATE ION × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.6；293 K；2.0M Ammonium sulfate, 0.1M Tri-sodium citrate, 0.2M Potassium sodium tartrate, pH 5.6, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.60 Å R-free 0.231 |
| 3VTV Crystal structure of Optineurin LIR-fused human LC3B_2-119 Deposited 2012-06-08 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP RESIDUES 170-181, RESIDUES 2-119
|
Mutation：S170E, S171E, S173E, S174E, S177E | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；2.0M Ammonium sulfate, 0.05M Tri-sodium citrate, 0.1M Potassium sodium tartrate, 10% PEG 3350, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.70 Å R-free 0.252 |
| 3VTW Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 Deposited 2012-06-08 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP RESIDUES 170-181, RESIDUES 2-119
|
Mutation：S170E, S171E, S173E, S174E, S177E | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；2.0M Ammonium sulfate, 0.05M Tri-sodium citrate, 0.1M Potassium sodium tartrate, 5% Glycerol, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.52 Å R-free 0.280 |
| 3VTW Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 Deposited 2012-06-08 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–119（118 aa）
Fragment：UNP RESIDUES 170-181, RESIDUES 2-119
|
Mutation：S170E, S171E, S173E, S174E, S177E | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；2.0M Ammonium sulfate, 0.05M Tri-sodium citrate, 0.1M Potassium sodium tartrate, 5% Glycerol, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.52 Å R-free 0.280 |
| 3VTW Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 Deposited 2012-06-08 | Assembly 3 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
2–119（118 aa）
Fragment：UNP RESIDUES 170-181, RESIDUES 2-119
|
Mutation：S170E, S171E, S173E, S174E, S177E | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；2.0M Ammonium sulfate, 0.05M Tri-sodium citrate, 0.1M Potassium sodium tartrate, 5% Glycerol, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 2.52 Å R-free 0.280 |
| 3WAO Crystal structure of Atg13 LIR-fused human LC3B_2-119 Deposited 2013-05-06 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：RESIDUES 436-447, RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；0.1M Sodium citrate tribasic dihydrate 10% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.60 Å R-free 0.294 |
| 3WAO Crystal structure of Atg13 LIR-fused human LC3B_2-119 Deposited 2013-05-06 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–119（118 aa）
Fragment：RESIDUES 436-447, RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；0.1M Sodium citrate tribasic dihydrate 10% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.60 Å R-free 0.294 |
| 3WAO Crystal structure of Atg13 LIR-fused human LC3B_2-119 Deposited 2013-05-06 | Assembly 3 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
2–119（118 aa）
Fragment：RESIDUES 436-447, RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；0.1M Sodium citrate tribasic dihydrate 10% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.60 Å R-free 0.294 |
| 3WAO Crystal structure of Atg13 LIR-fused human LC3B_2-119 Deposited 2013-05-06 | Assembly 4 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain D
2–119（118 aa）
Fragment：RESIDUES 436-447, RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；0.1M Sodium citrate tribasic dihydrate 10% PEG 3350, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.60 Å R-free 0.294 |
| 3X0W Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 Deposited 2014-10-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1M Acetate, pH 5.0, 1.4M Ammonium Sulfate, 0.1M NaCl, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.71 Å R-free 0.294 |
| 3X0W Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 Deposited 2014-10-22 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–119（118 aa）
Fragment：UNP RESIDUES 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；293 K；0.1M Acetate, pH 5.0, 1.4M Ammonium Sulfate, 0.1M NaCl, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.71 Å R-free 0.294 |
| 4WAA Crystal structure of Nix LIR-fused human LC3B_2-119 Deposited 2014-08-29 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: Monomeric（2） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP residues 2-119
Chain B
2–119（118 aa）
Fragment：UNP residues 2-119
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4；300 K；20% PEG3350, 8% Tacsimate pH 4
|
Resolution 2.35 Å R-free 0.273 |
| 5D94 Crystal structure of LC3-LIR peptide complex Deposited 2015-08-18 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1M Potassium thiocyanate, 30%(w/v) Polyethylene glycol monomethyl ether 2000
|
Resolution 1.53 Å R-free 0.215 |
| 5DCN Crystal structure of LC3 in complex with TECPR2 LIR Deposited 2015-08-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP residues 2-119
|
Not recorded | SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；1.8M Lithium sulphate, 0.01M Magnesium chloride, 0.05M MES monohydrate, pH5.6
|
Resolution 2.00 Å R-free 0.247 |
| 5GMV LC3B-FUNDC1 complex Deposited 2016-07-17 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；30% PEG MME 2000, 0.1mM sodium cacodylate (pH 6.0)
|
Resolution 2.25 Å R-free 0.272 |
| 5GMV LC3B-FUNDC1 complex Deposited 2016-07-17 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；30% PEG MME 2000, 0.1mM sodium cacodylate (pH 6.0)
|
Resolution 2.25 Å R-free 0.272 |
| 5MS2 Crystal structure of the Legionella pneumophila effector protein RavZ in complex with human LC3B Deposited 2016-12-30 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–119（119 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；277.15 K；0.17 M ammonium acetate, 0.085M tri sodium citrate, 25.5% PEG 4000 and 15% glycerol
|
Resolution 2.47 Å R-free 0.238 |
| 5MS5 Low-salt structure of RavZ LIR2-fused human LC3B Deposited 2016-12-31 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
|
Not recorded | SO4 SULFATE ION × 2 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293.15 K；0.1 M citric acid anhydrous and 1.6 M ammonium sulfate
|
Resolution 1.53 Å R-free 0.242 |
| 5MS5 Low-salt structure of RavZ LIR2-fused human LC3B Deposited 2016-12-31 | Assembly 2 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–119（118 aa）
|
Not recorded | SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293.15 K；0.1 M citric acid anhydrous and 1.6 M ammonium sulfate
|
Resolution 1.53 Å R-free 0.242 |
| 5MS6 High-salt structure of RavZ LIR2-fused human LC3B Deposited 2016-12-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；277.15 K；0.1 M sodium acetate and 3 M NaCl
|
Resolution 1.90 Å R-free 0.261 |
| 5MS6 High-salt structure of RavZ LIR2-fused human LC3B Deposited 2016-12-31 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
2–119（118 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；277.15 K；0.1 M sodium acetate and 3 M NaCl
|
Resolution 1.90 Å R-free 0.261 |
| 5V4K Crystal structure of NEDD4 LIR-fused human LC3B_2-119 Deposited 2017-03-09 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–119（118 aa）
Fragment：UNP residues 2-119,UNP residues 2-119,UNP residues 2-119,UNP residues 2-119
Chain B
2–119（118 aa）
Fragment：UNP residues 2-119,UNP residues 2-119,UNP residues 2-119,UNP residues 2-119
|
Not recorded | GOL GLYCEROL × 2 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；277 K；0.1M Sodium Acetate pH 5.0, 1.2M Ammonium Sulfate
|
Resolution 2.10 Å R-free 0.233 |
| 5W9A The structure of the Trim5alpha Bbox- coiled coil in complex LC3B Deposited 2017-06-22 | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
4–117（114 aa）
Fragment：UNP residues 2-119
Chain D
4–117（114 aa）
Fragment：UNP residues 2-119
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；291 K；0.2 M NH4Cl, 0.1 M Tris pH8, 20% PEG 6,000
|
Resolution 2.74 Å R-free 0.274 |
| 5XAC CLIR - LC3B Deposited 2017-03-12 | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–120（119 aa）
Chain B
2–120（119 aa）
Chain C
2–120（119 aa）
Chain D
2–120（119 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；PEG 3,350, 0.1M HEPES pH 7.5, 200mM NaCl.
|
Resolution 1.70 Å R-free 0.245 |
| 5XAD NLIR - LC3B fusion protein Deposited 2017-03-12 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–120（119 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 9.5；293 K；1.0 M Ammonium sulfate, 100mM CHES/NaOH pH 9.5, 200mM NaCl.
|
Resolution 1.88 Å R-free 0.253 |
| 5XAD NLIR - LC3B fusion protein Deposited 2017-03-12 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
2–120（119 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 9.5；293 K；1.0 M Ammonium sulfate, 100mM CHES/NaOH pH 9.5, 200mM NaCl.
|
Resolution 1.88 Å R-free 0.253 |
| 5XAE mutNLIR_LC3B Deposited 2017-03-12 | Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
2–120（119 aa）
Chain B
2–120（119 aa）
Chain C
2–120（119 aa）
Chain D
2–120（119 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；293 K；Pentaerythritol propoxylate, 0.1M HEPES pH 7.0, 0.2M Potassium chloride.
|
Resolution 2.00 Å R-free 0.259 |
| 6J04 Crystal structure of full length human LC3B delta G120 mutant (2_125) Deposited 2018-12-21 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
2–125（124 aa）
Fragment：UNP residues 2-125
Chain C
2–125（124 aa）
Fragment：UNP residues 2-125
|
Mutation：deletion mutant G120 Mutation：deletion mutant G120 | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；0.16M ammonium sulfate, 0.08M sodium acetate pH4.6, 20% (w/v) PEG4000; 20% (v/v) glycerol
|
Resolution 1.90 Å R-free 0.262 |
| 6J04 Crystal structure of full length human LC3B delta G120 mutant (2_125) Deposited 2018-12-21 | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
2–125（124 aa）
Fragment：UNP residues 2-125
Chain D
2–125（124 aa）
Fragment：UNP residues 2-125
|
Mutation：deletion mutant G120 Mutation：deletion mutant G120 | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；0.16M ammonium sulfate, 0.08M sodium acetate pH4.6, 20% (w/v) PEG4000; 20% (v/v) glycerol
|
Resolution 1.90 Å R-free 0.262 |
| 6LAN Structure of CCDC50 and LC3B complex Deposited 2019-11-12 | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–125（124 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；294 K；20% v/v 2-Propanol, 0.1 M sodium citrate pH 5.6, 20% w/v PEG 2000 MME
|
Resolution 1.41 Å R-free 0.219 |
| 7ELG LC3B modificated with a covalent probe Deposited 2021-04-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
2–119（118 aa）
|
Not recorded | 8Z6 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293.15 K；2.0M ammonium sulfate, 0.1M tri-sodium citrate (pH 5.6), 0.2M potassium sodium tartrate
|
Resolution 1.60 Å R-free 0.231 |
| 7GA8 PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198158918 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K4R 1H-indazole-3-carbonitrile × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.87 Å R-free 0.274 |
| 7GA9 PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198177230 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K6U (2M)-2-(2-methoxyphenyl)-1,3,4-oxadiazole × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.17 Å R-free 0.246 |
| 7GAA PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1198233191 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K7L (4S)-imidazo[1,2-a]pyrimidine-5,7-diol × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.03 Å R-free 0.248 |
| 7GAB PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1255402624 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | EYK 2-tert-butylbenzene-1,4-diol × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.23 Å R-free 0.276 |
| 7GAC PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1456069604 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | KF8 N-[(3S)-piperidin-3-yl]benzamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.91 Å R-free 0.260 |
| 7GAD PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1667545918 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K8L N-[(1,3-thiazol-5-yl)methyl]acetamide × 2 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.86 Å R-free 0.258 |
| 7GAE PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z1688504114 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | GV4 2-cyano-~{N}-(1,3,5-trimethylpyrazol-4-yl)ethanamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.92 Å R-free 0.251 |
| 7GAF PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z183352334 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K96 N-{[(2R)-oxolan-2-yl]methyl}morpholine-4-carboxamide × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.84 Å R-free 0.245 |
| 7GAG PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z198195770 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | LJA N-[3-(carbamoylamino)phenyl]acetamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.59 Å R-free 0.215 |
| 7GAH PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z2033637875 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | LRF N~2~-(4-cyano-3-methyl-1,2-thiazol-5-yl)-N~2~-methylglycinamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.90 Å R-free 0.254 |
| 7GAI PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z212122838 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K9N N-[(4-methyl-1,3-thiazol-2-yl)methyl]cyclobutanecarboxamide × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.97 Å R-free 0.281 |
| 7GAJ PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z285233820 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | KB3 (5M)-5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-amine × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.89 Å R-free 0.229 |
| 7GAK PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z287121492 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | KA3 N-(cyclopropylmethyl)-4-methoxypiperidine-1-carboxamide × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.77 Å R-free 0.250 |
| 7GAL PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z291279160 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | LV4 1-[2-(trifluoromethyloxy)phenyl]thiourea × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.91 Å R-free 0.251 |
| 7GAM PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z373768900 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | NUA N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.75 Å R-free 0.234 |
| 7GAN PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z56767614 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | RWP methyl 4-[(trifluoroacetyl)amino]benzoate × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.09 Å R-free 0.256 |
| 7GAO PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z57450788 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | RV4 N-{4-[(morpholin-4-yl)methyl]phenyl}acetamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.69 Å R-free 0.218 |
| 7GAP PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z728939702 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | KCC N-methylquinoxalin-2-amine × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.68 Å R-free 0.244 |
| 7GAQ PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z755044716 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | K0J N-ethyl-1H-1,2,3-triazole-4-carboxamide × 1 EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.14 Å R-free 0.244 |
| 7GAR PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z820676436 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | 2NU 2-(4-bromanylpyrazol-1-yl)-~{N}-cyclopropyl-~{N}-methyl-ethanamide × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 2.07 Å R-free 0.264 |
| 7GAS PanDDA analysis group deposition -- Crystal Structure of MAP1LC3B in complex with Z952016136 Deposited 2023-08-10 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | KBU 4-chloro-1H-benzimidazole × 1 EDO 1,2-ETHANEDIOL × 8 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.91 Å R-free 0.276 |
| 7GAU PanDDA analysis group deposition of ground-state model of MAP1LC3B Deposited 2023-08-11 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–120（120 aa）
|
Mutation：TruncationafterGly120 | EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.59 Å R-free 0.217 |
| 8Q53 Crystal structure of truncated human Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) in apo form Deposited 2023-08-08 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1–125（125 aa）
|
Mutation：Truncation after Gly120 | EDO 1,2-ETHANEDIOL × 9 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4.7；293 K；36% PEG 8000, 0.1M acetate pH 4.7
|
Resolution 1.36 Å R-free 0.210 |
| 8Q7K IRGQ LIR2 peptide in complex with LC3B Deposited 2023-08-16 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4；293 K；1 M lithium chloride, 0.1 M citrate, 20% PEG 6000
|
Resolution 1.60 Å R-free 0.213 |
| 8Q7K IRGQ LIR2 peptide in complex with LC3B Deposited 2023-08-16 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1–125（125 aa）
|
Not recorded | EDO 1,2-ETHANEDIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 4；293 K；1 M lithium chloride, 0.1 M citrate, 20% PEG 6000
|
Resolution 1.60 Å R-free 0.213 |
| 8YV6 Crystal structure of LC3B in complex with Influenza A virus M2 peptide Deposited 2024-03-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–125（125 aa）
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；30% Jeffamine, 0.1M HEPES, pH 7.0
|
Resolution 1.75 Å R-free 0.250 |
| 9VUY NMR Structure of LC3B in complex with HBx BH3-like motif Deposited 2025-07-14 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1–119（119 aa）
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 50；Pressure 1
NMR sample composition
0.4 mM [U-13C; U-15N] LC3B, 0.5 mM [U-13C; U-15N] HBx BH3-like motif, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.8 mM 1H LC3B, 0.4 mM [U-13, U-15N] HBx BH3-like motif, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.4 mM [U-15N] LC3B, 0.5 mM [U-15N] HBx BH3-like motif, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.5 mM [U-13, U-15N] LC3B, 0.625 mM 1H HBx BH3-like motif, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |