Current Protein Identity:Q9HAW0
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4ROC Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter Deposited 2014-10-28 | Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain A
62–419(358 aa)
|
Not recorded | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.9;293 K;10-20% PEG 3350, 50-100 mM MgCl2, 2 mM DTT, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.215 |
| 4ROD Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter Deposited 2014-10-28 | Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain A
62–419(358 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.9;293 K;10-20% PEG 3350, 50-100 mM MgCl2, 2 mM DTT, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.70 Å R-free 0.247 |
| 4ROE Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter Deposited 2014-10-28 | Assembly 1 Protein–DNA Heteromer;Protein × 2 PDB declaration: tetrameric(4) Consistent with all polymers |
Chain A
62–419(358 aa)
|
Not recorded | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.9;293 K;10-20% PEG 3350, 50-100 mM MgCl2, 2 mM DTT, pH 7.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.20 Å R-free 0.222 |
| 5N9G TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1- Deposited 2017-02-24 | Assembly 1 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain A
62–419(358 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;10-16% PEG 8000,
150-200 mM KCl,
100 mM MES pH 6.5,
10-15 mM MgCl2,
1 mM TCEP
|
Resolution 2.70 Å R-free 0.234 |
| 5N9G TFIIIB -TBP/Brf2/DNA and SANT domain of Bdp1- Deposited 2017-02-24 | Assembly 2 Protein–DNA Heteromer;Protein × 3 PDB declaration: pentameric(5) Consistent with all polymers |
Chain F
62–419(358 aa)
|
Not recorded | NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;10-16% PEG 8000,
150-200 mM KCl,
100 mM MES pH 6.5,
10-15 mM MgCl2,
1 mM TCEP
|
Resolution 2.70 Å R-free 0.234 |
| 8ITY human RNA polymerase III pre-initiation complex closed DNA 1 Deposited 2023-03-23 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 7 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.90 Å |
| 8IUE RNA polymerase III pre-initiation complex melting complex 1 Deposited 2023-03-24 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 8 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 4.10 Å |
| 8IUH RNA polymerase III pre-initiation complex open complex 1 Deposited 2023-03-24 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 8 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.40 Å |
| 9FSO Human RNA Polymerase III Class III Open Pre-initiation Complex 1 (OC1) Deposited 2024-06-21 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain S
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 9 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.28 Å |
| 9FSP RNA Polymerase III Class III Open Pre-initation Complex 2 (OC2) Deposited 2024-06-21 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain S
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 9 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.39 Å |
| 9FSQ RNA Polymerase III Class III Melting Pre-Initiation Complex (MC) Deposited 2024-06-21 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain S
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 9 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.51 Å |
| 9FSR RNA Polymerase III Class III Open Mini Pre-initiation Complex 1 (OC1-mini) Deposited 2024-06-21 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain S
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 9 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.76 Å |
| 9FSS RNA Polymerase III Class III Open Mini Pre-Initiation complex 2 (OC2-mini) Deposited 2024-06-21 | Assembly 1 Protein–DNA Heteromer;Protein × 23 PDB declaration: 25-meric(25) Consistent with all polymers |
Chain S
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 9 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.14 Å |
| 9K2G Human RNA Polymerase III de novo transcribing complex 13 (TC13) Deposited 2024-10-17 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.00 Å |
| 9K36 Human RNA Polymerase III de novo transcribing complex 12 (TC12) Deposited 2024-10-18 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.90 Å |
| 9K38 Human RNA Polymerase III de novo transcribing complex 6 (TC6) Deposited 2024-10-18 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.10 Å |
| 9K39 Human RNA Polymerase III de novo transcribing complex 8 (TC8) Deposited 2024-10-18 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.80 Å |
| 9K3B Human RNA Polymerase III de novo transcribing complex 10 overall (TC10-overall) Deposited 2024-10-18 | Assembly 1 Other combination Heteromer;Protein × 23 PDB declaration: 26-meric(26) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 4.80 Å |
| 9K3U Human RNA Polymerase III de novo transcribing complex 5 (TC5) Deposited 2024-10-20 | Assembly 1 Other combination Heteromer;Protein × 23 PDB declaration: 26-meric(26) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 7 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.00 Å |
| 9K3V Human RNA Polymerase III de novo transcribing complex 4 (TC4) Deposited 2024-10-20 | Assembly 1 Other combination Heteromer;Protein × 23 PDB declaration: 26-meric(26) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 7 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 MG MAGNESIUM ION × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.50 Å |
| 9LKT Human RNA Polymerase III de novo transcribing complex 10 (TC10) Deposited 2025-01-16 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.50 Å |
| 9LXN Human RNA Polymerase III de novo transcribing complex 5 (TC5)(without 3'dATP) Deposited 2025-02-18 | Assembly 1 Other combination Heteromer;Protein × 23 PDB declaration: 26-meric(26) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 7 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.30 Å |
| 9LXO Human RNA Polymerase III de novo transcribing complex 6 (TC6)(without 3'dATP) Deposited 2025-02-18 | Assembly 1 Other combination Heteromer;Protein × 18 PDB declaration: 21-meric(21) Consistent with all polymers |
Chain V
1–419(419 aa)
|
Not recorded | ZN ZINC ION × 6 MG MAGNESIUM ION × 1 SF4 IRON/SULFUR CLUSTER × 1 GTP GUANOSINE-5'-TRIPHOSPHATE × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.60 Å |