Current Protein Identity:Q9HD67
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2LW9 NMR solution structure of Myo10 anti-CC Deposited 2012-07-25 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
883–933(51 aa)
Chain B
883–933(51 aa)
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6.5;303 K;Ionic strength (raw mmCIF value) 100
NMR sample composition
0.8 mM [U-100% 13C; U-100% 15N] entity-1, 100% D2O | 100% D2O
|
Resolution not provided |
| 3AU4 Structure of the human myosin-X MyTH4-FERM cassette bound to its specific cargo, DCC Deposited 2011-01-28 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1486–2058(573 aa)
Fragment:MyTH4-FERM cassette, UNP residues 1486-2058
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8;293 K;100mM maric acid-MES-Tris (MMT) buffer, 2% PEG 1500, pH 8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.90 Å R-free 0.233 |
| 3AU5 Structure of the human myosin-X MyTH4-FERM cassette Deposited 2011-01-28 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1486–2058(573 aa)
Fragment:MyTH4-FERM cassette, UNP residues 1486-2058
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;10% PEG 8000, 5% MPD, 0.1M HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.55 Å R-free 0.281 |
| 3AU5 Structure of the human myosin-X MyTH4-FERM cassette Deposited 2011-01-28 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1486–2058(573 aa)
Fragment:MyTH4-FERM cassette, UNP residues 1486-2058
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;293 K;10% PEG 8000, 5% MPD, 0.1M HEPES, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.55 Å R-free 0.281 |
| 3PZD Structure of the myosin X MyTH4-FERM/DCC complex Deposited 2010-12-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1503–2047(545 aa)
Fragment:MyTH4-FERM tandem
|
Not recorded | GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;289 K;8% PEG 8000, 10% glycerol, HEPES buffer, pH 7.5, vapor diffusion, hanging drop, temperature 289K
|
Resolution 2.50 Å R-free 0.259 |
| 5I0H Crystal structure of myosin X motor domain in pre-powerstroke state Deposited 2016-02-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
1–741(741 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 EDO 1,2-ETHANEDIOL × 8 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;277 K;10% PEG 8000, 50mM Tris pH 7.5, 1mM TCEP and 125mM Lithium sulfate
|
Resolution 1.80 Å R-free 0.190 |
| 5I0H Crystal structure of myosin X motor domain in pre-powerstroke state Deposited 2016-02-04 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
1–741(741 aa)
|
Not recorded | ADP ADENOSINE-5'-DIPHOSPHATE × 1 MG MAGNESIUM ION × 1 BEF BERYLLIUM TRIFLUORIDE ION × 1 EDO 1,2-ETHANEDIOL × 10 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7.5;277 K;10% PEG 8000, 50mM Tris pH 7.5, 1mM TCEP and 125mM Lithium sulfate
|
Resolution 1.80 Å R-free 0.190 |
| 5I0I Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state Deposited 2016-02-04 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
3–793(791 aa)
|
Not recorded | MPO 3[N-MORPHOLINO]PROPANE SULFONIC ACID × 1 MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;277 K;7.5% PEG 10000, 100mM MOPS pH 7.0, 1mM TCEP and 50mM Magnesium acetate
|
Resolution 3.15 Å R-free 0.218 |
| 5I0I Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state Deposited 2016-02-04 | Assembly 2 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
3–793(791 aa)
|
Not recorded | MPO 3[N-MORPHOLINO]PROPANE SULFONIC ACID × 1 MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 7;277 K;7.5% PEG 10000, 100mM MOPS pH 7.0, 1mM TCEP and 50mM Magnesium acetate
|
Resolution 3.15 Å R-free 0.218 |
| 5KG8 Rigor myosin X co-complexed with an actin filament Deposited 2016-06-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
3–741(739 aa)
Fragment:motor domain (UNP residues 3-741)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 6.8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 9.10 Å |