当前蛋白身份：Q9UIC8
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 2 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 B
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 3 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 C
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 4 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 D
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 5 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 E
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 6 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 F
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 7 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 G
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3IEI Crystal structure of human leucine carboxylmethyltransferase-1 in complex with S-adenosyl homocysteine 提交 2009-07-22 | Assembly 8 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 H
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 GOL GLYCEROL × 1 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；Protein solution (10 mg/ml LCMT-1, 5 mM SAH) was mixed with an equal volume of reservoir solution containing 17-19% v/v PEG MME 2000, 150 mM Triethylamine N-oxide, 5 mM DTT, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
分辨率 1.90 Å R-free 0.232 |
| 3O7W The Crystal Structure of Human Leucine Carboxyl Methyltransferase 1 提交 2010-08-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
23–334（312 aa）
片段：UNP residues 23-334 with deletion of residues 233-258
|
未记录 | GOL GLYCEROL × 1 SAM S-ADENOSYLMETHIONINE × 1 NA SODIUM ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；295 K；0.05 M Ammonium Sulfate, 0.05M Bis Tris (pH6.5), 30% Pentaerythritol Ethoxylate, VAPOR DIFFUSION, SITTING DROP, temperature 295K
|
分辨率 2.00 Å R-free 0.265 |
| 3P71 Crystal structure of the complex of LCMT-1 and PP2A 提交 2010-10-11 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 2 PDB 声明：dimeric（2） 与蛋白数一致 |
链 T
1–334（334 aa）
|
突变：C19M, A21E, D22N, P115S | PEG DI(HYDROXYETHYL)ETHER × 1 AN6 5'-{[(3S)-3-amino-3-carboxypropyl](ethyl)amino}-5'-deoxyadenosine × 1 MN MANGANESE (II) ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 8.2；291 K；PROTEIN COMPLEX (~5 MG/ML), 100MM TRIS-HCL, 22-26% V/V PEG 4000, 200 MM SODIUM ACETATE, 5 MM DTT, pH 8.2, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
分辨率 2.70 Å R-free 0.249 |