Current Protein Identity:Q9UMW8 New Search
Main Difference Dimensions in This Set
Different construct Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
9QY8 Crystal structure of apoform human USP18 Deposited 2025-04-17 Assembly 1 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain A 49–285(237 aa)
Chain A 300–372(73 aa)
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;277 K;0.2 M sodium citrate tribasic dihydrate, 0.1 M Bis-Tris propane, pH 7.5, 20 % (w/v) PEG3350
Resolution 1.92 Å R-free 0.260
9QY8 Crystal structure of apoform human USP18 Deposited 2025-04-17 Assembly 2 Insufficient information Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count
Chain B 49–285(237 aa)
Chain B 300–372(73 aa)
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP;pH 7.5;277 K;0.2 M sodium citrate tribasic dihydrate, 0.1 M Bis-Tris propane, pH 7.5, 20 % (w/v) PEG3350
Resolution 1.92 Å R-free 0.260
9ZFO Cryo-EM Structure of Human STAT2-USP18-ISG15 Complex Deposited 2025-12-01 Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count
Chain U 26–372(347 aa)
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8;25mM HEPES (pH 8.0), 200mM NaCl and 1.0mM TCEP
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.05 Å