Current Protein Identity:S5ME50
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 8PNP Influenza A/H7N9 polymerase in pre-initiation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A Deposited 2023-06-30 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: pentameric(5) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.49 Å |
| 8PNQ Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A Deposited 2023-06-30 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | 2KH 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine × 1 MG MAGNESIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.88 Å |
| 8R3K Influenza A/H7N9 polymerase in self-stalled pre-termination state, with Pol II pS5 CTD peptide mimic bound in site 1A/2A. Deposited 2023-11-09 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | POP PYROPHOSPHATE 2- × 1 MG MAGNESIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.43 Å |
| 8R3L Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A Deposited 2023-11-09 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.25 Å |
| 8RMP Influenza polymerase A/H7N9-4M (ENDO(R) | Core1) Deposited 2024-01-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
1–757(757 aa)
|
Mutation:K577G | MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.77 Å |
| 8RMQ Influenza polymerase A/H7N9-4M (ENDO(R) | Core2) Deposited 2024-01-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
1–757(757 aa)
|
Mutation:K577G | MG MAGNESIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.54 Å |
| 8RMR Influenza polymerase A/H7N9-4M replication complex, an asymmetric polymerase dimer bound to human ANP32A Deposited 2024-01-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 7 PDB declaration: heptameric(7) Consistent with protein count |
Chain B
1–757(757 aa)
Chain E
1–757(757 aa)
|
Mutation:K577G Mutation:K577G | MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.25 Å |
| 8RMS Influenza polymerase A/H7N9-4M replicase minus 627(R) (from "Influenza polymerase A/H7N9-4M replication complex" | Local refinement) Deposited 2024-01-08 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain B
1–757(757 aa)
|
Mutation:K577G | MG MAGNESIUM ION × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.21 Å |
| 8RN0 Influenza polymerase A/H7N9-4M encapsidase plus 627(R) / human ANP32A (from "Influenza polymerase A/H7N9-4M replication complex" | Local refinement) Deposited 2024-01-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 5 PDB declaration: pentameric(5) Consistent with protein count |
Chain E
1–757(757 aa)
|
Mutation:K577G | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.13 Å |
| 9RAF Influenza A/H7N9 polymerase in complex with a 70-mer template in stalled elongation with backtracking and stem. Deposited 2025-05-20 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | MG MAGNESIUM ION × 3 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.15 Å |
| 9RAG Influenza A/H7N9 polymerase in complex with a 70-mer RNA template, in stalled elongation. Deposited 2025-05-20 | Assembly 1 Protein–RNA Heteromer;Protein × 4 PDB declaration: hexameric(6) Consistent with all polymers |
Chain B
1–757(757 aa)
|
Mutation:K577G | MG MAGNESIUM ION × 3 POP PYROPHOSPHATE 2- × 1 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 1.99 Å |