Leishmania braziliensis SGT co-chaperone

{
  "code": "SASDC75",
  "status": "Published",
  "type_of_curve": "Merged",
  "angular_unit": "1/nm",
  "project": {
    "title": "Structural and functional studies of the Leishmania braziliensis SGT co-chaperone indicate that it shares structural features with HIP and can interact with both Hsp90 and Hsp70 with similar affinities.",
    "publication": {
      "title": "Structural and functional studies of the Leishmania braziliensis SGT co-chaperone indicate that it shares structural features with HIP and can interact with both Hsp90 and Hsp70 with similar affinities.",
      "author_list": "Coto ALS, Seraphim TV, Batista FAH, Dores-Silva PR, Barranco ABF, Teixeira FR, Gava LM, Borges JC",
      "journal": "Int J Biol Macromol",
      "doi": "10.1016/j.ijbiomac.2018.06.123",
      "pmid": "29959008",
      "published_date": "2018 Oct 15"
    },
    "status": "released",
    "submitted_date": "2017-06-17",
    "released_date": "2018-07-03"
  },
  "pddf_data": "https://www.sasbdb.org/media/p_of_R_files/SASDC75.out",
  "intensities_data": "https://www.sasbdb.org/media/intensities_files/SASDC75.dat",
  "intensities_log_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDC75_dat_img.png",
  "intensities_kratky_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDC75_kratky_img.png",
  "pddf_plot": "https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDC75_pofr_img.png",
  "intensities_guinier_plot": "https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDC75_guinier_img.png",
  "sascif_data": "https://www.sasbdb.org/media/sascif/sascif_files/SASDC75.sascif",
  "experiment": {
    "instrument": {
      "detector": {
        "type": null,
        "name": "MAR 165 CCD",
        "resolution": null
      },
      "name": "Brazilian Synchrotron Light Laboratory",
      "city": "Campinas",
      "country": "Brazil",
      "beamline_name": "SAXS2 Beamline",
      "beam_geometry": "",
      "type_of_source": "X-ray synchrotron",
      "point_source": null,
      "line_collimation": null,
      "sample_path_length": null,
      "line_collimation_slitlength": null,
      "line_collimation_integrationwidth": null,
      "xray_energy": null,
      "beam_profile_ah": null,
      "beam_profile_al": null
    },
    "sample": {
      "molecule": [
        {
          "long_name": "SGT protein",
          "short_name": "LbSGT",
          "sequence": "GSHMEEKDQPITDDHRKLVFSFLRMMRRSKVENPERTEAVAQMLGEEFGVDPAGSGGLHDTEV\r\nDVLEAFKTALREHERRSGAEQDEKFMSFVELLEKKGYFKGVEKGSDEYAQRLEKARDKFN\r\nQRNNPYEGLTAEQIKNKGNELMSQAKYKEAIAYYTKAIELESDNAVFFANRAAAHTHLKD\r\nYSNAIIDCERAIVINPEYSKSYSRLGTALFYQENYARAVEAFTKACDLDPDNDTYKEDLK\r\nRAEEKAKMTGLTTGGGMGGFPGMGGFPGMGGMPDMSQFASMMNNPQFMETAQRMMQNPEF\r\nSNMVANMAGKFSQGGMDPAELNRLGADMGMRNVDEEGNVVTPFGKVNRAAIEKLQEEEVR\r\nKNPKLAGIMADVQANGYGAFQKYLGDPDVMSLMMKFQSLMFTNPNSSA",
          "organism": "Leishmania braziliensis",
          "uniprot_code": "A4HIK6",
          "uniprot_range_first": null,
          "uniprot_range_last": null,
          "oligomerization": "dimer",
          "molecular_type": "protein",
          "uniprot_sequence": "MEEKDQPITDDHRKLVFSFLRMMRRSKVENPERTEAVAQMLGEEFGVDPAGSGGLHDTEV\nDVLEAFKTALREHERRSGAEQDEKFMSFVELLEKKGYFKGVEKGSDEYAQRLEKARDKFN\nQRNNPYEGLTAEQIKNKGNELMSQAKYKEAIAYYTKAIELESDNAVFFANRAAAHTHLKD\nYSNAIIDCERAIVINPEYSKSYSRLGTALFYQENYARAVEAFTKACDLDPDNDTYKEDLK\nRAEEKAKMTGLTTGGGMGGFPGMGGFPGMGGMPDMSQFASMMNNPQFMETAQRMMQNPEF\nSNMVANMAGKFSQGGMDPAELNRLGADMGMRNVDEEGNVVTPFGKVNRAAIEKLQEEEVR\nKNPKLAGIMADVQANGYGAFQKYLGDPDVMSLMMKFQSLMFTNPNSSA",
          "mw": 45.935,
          "total_mw": 91.87,
          "number_molecules": 2,
          "complex_state": false,
          "deuteration": null,
          "molecule_source": "biological",
          "molecule_description": null
        }
      ],
      "buffer": {
        "name": "20 mM Potassium Phosphate, 100 mM KCl, 10 mM EDTA, 1 mM B-mercaptoethanol",
        "concentration_unit": null,
        "comment": null,
        "additive": null,
        "concentration": null,
        "pka": null,
        "ph": 7.5,
        "deuteration": null
      },
      "purity_method": null,
      "name": "Leishmania braziliensis SGT co-chaperone",
      "ext_coefficient": null,
      "contrast": null,
      "specific_vol": null,
      "dry_vol": null,
      "absorbption": null,
      "deuteration": null,
      "mixture": null
    },
    "contributor": [
      {
        "affiliation": [
          {
            "short_name": null,
            "address": "São Carlos - SP - Brasil",
            "full_name": "Instituto de Química de São Carlos",
            "webpage": ""
          }
        ],
        "contributor_name": "Júlio",
        "contributor_surname": "Borges",
        "orcid": null
      }
    ],
    "concentration_method": null,
    "concentration_unit": null,
    "date": "2014-05-14",
    "storage_temperature": 4.0,
    "cell_temperature": 20.0,
    "exposure_time": 300.0,
    "number_of_frames": 3,
    "wavelength": 0.1488,
    "sample_detector_distance": 1.0,
    "concentration_min": 1.5,
    "concentration_max": 6.0,
    "sample_volume": null,
    "flow_rate": null,
    "s_min": 0.154,
    "s_max": 3.329,
    "total_exposure_time": null,
    "seccolumn": null
  },
  "fits": [
    {
      "models": [
        {
          "model_plot": "https://www.sasbdb.org/media/pdb_file/images/SASDC75_fit1_model1_img.png",
          "software": "DAMFILT",
          "pdb_link": [],
          "model_title": null,
          "type_of_model": "dummy",
          "software_version": "4.1",
          "model_data": "https://www.sasbdb.org/media/pdb_file/SASDC75_fit1_model1.pdb",
          "model_mw": 71.6,
          "bead_radius": null,
          "log": null,
          "symmetry": "P2",
          "comment": "",
          "user": 161
        }
      ],
      "fit_unit": "1/A",
      "fit_plot": "https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDC75_fit1_fit_img.png",
      "software": "DAMMIN",
      "chi_square_value": 1.476,
      "p_value": 0.203609,
      "fit_residual_plot": "SASDC75_fit1_fitresiduals_img.png",
      "fit_data": "https://www.sasbdb.org/media/fitting_files/SASDC75_fit1.fir",
      "fit_log": "https://www.sasbdb.org/media/fitting_files/log_files/SGT_1.log",
      "software_version": "5.3",
      "description": null
    }
  ],
  "estimated_volume_method": null,
  "pddf_software": "ATSAS GNOM",
  "pddf_software_version": "4.6",
  "i0_calibration_standard": null,
  "description": null,
  "experiment_description": "SAXS experiments were performed at the D02A-SAXS2 beamline at the Brazilian Synchrotron Light Laboratory (LNLS, Campinas, São Paulo, Brazil). The X-ray scattering data (I(s) vs s, where s = 4πsinθ/λ and 2θ is the scattering angle; λ = 0.1488 nm) were acquired using a two-dimensional position-sensitive MAR-CCD detector. Measurements were performed using a monochromatic X-ray beam and a sample-to-detector distance of ~1,000 mm, corresponding to the scattering vector range of 0.015 < q < 0.35 Å-1. LbSGT samples were prepared at 1.5 mg/mL, 3.0 mg/mL, 4.5 mg/mL and 6.0 mg/mL. Successive frames (20, 60 and 300 sec) were collected to inspect for X-ray damage. Aggregation or inter-particle interference were not observed. The model depicts the averaged spatial representation of the protein (DAMFILT occupancy and volume-corrected bead model).",
  "tags": [],
  "intensity_unit": null,
  "experimental_mw": 91.0,
  "experimental_mw_error": null,
  "guinier_i0_mw": 102.0,
  "guinier_i0_mw_error": 4.0,
  "porod_mw": null,
  "porod_mw_error": null,
  "pddf_i0": 0.06631,
  "pddf_i0_error": 0.00296,
  "guinier_i0": 0.0659072,
  "guinier_i0_error": 0.00039,
  "pddf_rg": 4.66,
  "pddf_rg_error": 0.3,
  "guinier_rg": 4.48,
  "guinier_rg_error": 0.4,
  "pddf_dmax": 17.0,
  "pddf_dmax_error": 5.0,
  "porod_volume": null,
  "porod_volume_error": null,
  "estimated_volume": null,
  "estimated_volume_error": null,
  "guinier_point_first": 2,
  "guinier_point_last": 11,
  "pddf_point_first": null,
  "pddf_point_last": null,
  "i0_calibration_standard_data": null,
  "intensities_log_log_plot": "SASDC75_datloglog_img.png",
  "symmetry": null,
  "last_modified": "2019-12-06T13:07:15.624532+01:00",
  "bragg_peak": []
}

{
  "code": "SASDC75",
  "status": "success",
  "started_at": "2026-08-11T14:40:48.175875+00:00",
  "finished_at": "2026-08-11T14:40:55.629428+00:00",
  "source_last_modified": "2019-12-06T13:07:15.624532+01:00",
  "files": [
    {
      "status": "downloaded",
      "url": "https://www.sasbdb.org/rest-api/entry/summary/SASDC75/",
      "path": "/data/saxsdb/sasbdb/entries/75/sasdc75/source/summary.json",
      "size": 8267,
      "sha256": "df38a3dbc6452a23ded93d3e43e8f54f4f26975fe70b6c92a43d9e6a86582f59"
    },
    {
      "status": "downloaded",
      "url": "https://www.sasbdb.org/media/intensities_files/SASDC75.dat",
      "path": "/data/saxsdb/sasbdb/entries/75/sasdc75/source/SASDC75.dat",
      "size": 7256,
      "sha256": "918589adcd61ba194c6db24eb817f9bb5d466fd70a15b1b673317fecae88b0eb",
      "role": "curve"
    },
    {
      "status": "downloaded",
      "url": "https://www.sasbdb.org/media/p_of_R_files/SASDC75.out",
      "path": "/data/saxsdb/sasbdb/entries/75/sasdc75/source/SASDC75.out",
      "size": 24106,
      "sha256": "f009058b1c5327a8771444fcb303807cbd3991cb66a106ae5cda4c858f51d99c",
      "role": "pddf"
    },
    {
      "status": "downloaded",
      "url": "https://www.sasbdb.org/media/sascif/sascif_files/SASDC75.sascif",
      "path": "/data/saxsdb/sasbdb/entries/75/sasdc75/source/SASDC75.sascif",
      "size": 76742,
      "sha256": "1bbabf7c935d28bba475e871e39c301a7b3d0434b3b5dffeb281fa81059f683f",
      "role": "sascif"
    },
    {
      "status": "downloaded",
      "url": "https://www.sasbdb.org/media/zip_directories/SASDC75.zip",
      "path": "/data/saxsdb/sasbdb/entries/75/sasdc75/source/SASDC75.zip",
      "size": 16368,
      "sha256": "8f91a5616c79ebaa4cce4f82bccdcf6202c95785fc646a930ed52668c13ef3f2",
      "role": "full_entry_zip",
      "zip_member_count": 4,
      "zip_validation": "central_directory_readable"
    }
  ]
}