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1a9x

CARBAMOYL PHOSPHATE SYNTHETASE: CAUGHT IN THE ACT OF GLUTAMINE HYDROLYSIS

Method: X-RAY DIFFRACTION Dmax: 258.1 Å Quality: GOOD
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1. Protein Identity and Related Structures Protein Identity & Related Structures

CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN)

Escherichia coli

UniProt P00968

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 8 PDB declaration: octameric（8） Consistent with protein copy count Chain A； UniProt 1–1072 Chain C； UniProt 1–1072 Chain E； UniProt 1–1072 Chain G； UniProt 1–1072 Not recorded CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN) × 4 （P00907） PO4 PHOSPHATE ION × 15 MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 28 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
2 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 1–1072 Not recorded CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN) × 1 （P00907） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
3 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain G； UniProt 1–1072 Not recorded CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN) × 1 （P00907） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
4 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 1–1072 Not recorded CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN) × 1 （P00907） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
5 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain E； UniProt 1–1072 Not recorded CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN) × 1 （P00907） PO4 PHOSPHATE ION × 3 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 1A9X Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1BXR STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP Deposited 1998-10-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 1–1072（1072 aa）
Chain C 1–1072（1072 aa）
Chain E 1–1072（1072 aa）
Chain G 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 13 K POTASSIUM ION × 19 CL CHLORIDE ION × 14 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å
1BXR STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP Deposited 1998-10-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 5 CL CHLORIDE ION × 2 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å
1BXR STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP Deposited 1998-10-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 5 CL CHLORIDE ION × 4 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å
1BXR STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP Deposited 1998-10-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 4 CL CHLORIDE ION × 4 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å
1BXR STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP Deposited 1998-10-08 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 5 CL CHLORIDE ION × 4 ANP PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 1–1073（1073 aa）
Chain C 1–1073（1073 aa）
Chain E 1–1073（1073 aa）
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 16 PO4 PHOSPHATE ION × 6 ORN L-ornithine × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 1 ORN L-ornithine × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C3O CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE Deposited 1999-07-28 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 1–1073（1073 aa）
Chain C 1–1073（1073 aa）
Chain E 1–1073（1073 aa）
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 16 PO4 PHOSPHATE ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 GLN GLUTAMINE × 8 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；278 K；PEG-8000, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, BERYLLIUM FLUORIDE, ADENOSINE 5'-DIPHOSPHATE,L-ORNITHINE, L-GLUTAMINE, HEPPS, pH 7.4, BATCH, temperature 278K
Resolution 2.10 Å R-free 0.258
1CE8 CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP Deposited 1999-03-18 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 1–1073（1073 aa）
Chain C 1–1073（1073 aa）
Chain E 1–1073（1073 aa）
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 28 CL CHLORIDE ION × 12 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 8 IMP INOSINIC ACID × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å R-free 0.250
1CE8 CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP Deposited 1999-03-18 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 7 CL CHLORIDE ION × 3 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 2 IMP INOSINIC ACID × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å R-free 0.250
1CE8 CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP Deposited 1999-03-18 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 7 CL CHLORIDE ION × 3 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 2 IMP INOSINIC ACID × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å R-free 0.250
1CE8 CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP Deposited 1999-03-18 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 7 CL CHLORIDE ION × 3 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 2 IMP INOSINIC ACID × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å R-free 0.250
1CE8 CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP Deposited 1999-03-18 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 7 CL CHLORIDE ION × 3 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 2 IMP INOSINIC ACID × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.4
Resolution 2.10 Å R-free 0.250
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 1–1073（1073 aa）
Chain C 1–1073（1073 aa）
Chain E 1–1073（1073 aa）
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 33 CL CHLORIDE ION × 29 PO4 PHOSPHATE ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 8 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–1073（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 9 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–1072（1072 aa）
Chain E 1–1072（1072 aa）
Chain H 1–1072（1072 aa）
Chain K 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 16 K POTASSIUM ION × 29 PO4 PHOSPHATE ION × 9 CL CHLORIDE ION × 29 GLN GLUTAMINE × 8 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 7 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain H 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 6 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 8 PO4 PHOSPHATE ION × 3 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 1–1072（1072 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 8 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 8 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 0–1072（1073 aa）
Chain C 0–1072（1073 aa）
Chain E 0–1072（1073 aa）
Chain G 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 22 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 5 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 5 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 6 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 6 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1M6V Crystal Structure of the G359F (small subunit) Point Mutant of Carbamoyl Phosphate Synthetase Deposited 2002-07-17 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 0–1072（1073 aa）
Chain C 0–1072（1073 aa）
Chain E 0–1072（1073 aa）
Chain G 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 26 CL CHLORIDE ION × 28 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG-8000, manganese chloride, potassium chloride, ADP, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.245
1T36 Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate Deposited 2004-04-24 Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain A 0–1072（1073 aa）
Chain C 0–1072（1073 aa）
Chain E 0–1072（1073 aa）
Chain G 0–1072（1073 aa）
Not recorded MN MANGANESE (II) ION × 12 K POTASSIUM ION × 22 PO4 PHOSPHATE ION × 5 CL CHLORIDE ION × 27 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 U5P URIDINE-5'-MONOPHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, tetramethylammonium chloride, potassium chloride, manganese chloride, ornithine, ADP, HEPES, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.209

9 other PDB entries and 33 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name CARB_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–1073； UniProt 1–1072 Author chain C； PDBConstruct 2–1073； UniProt 1–1072 Author chain E； PDBConstruct 2–1073； UniProt 1–1072 Author chain G； PDBConstruct 2–1073； UniProt 1–1072

CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN)

Escherichia coli

UniProt P00907

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 8 PDB declaration: octameric（8） Consistent with protein copy count Chain B； UniProt 2–380 Chain D； UniProt 2–380 Chain F； UniProt 2–380 Chain H； UniProt 2–380 Mutation：H353N Non-standard monomer：Yes (specific site not provided by mmCIF) CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN) × 4 （P00968） PO4 PHOSPHATE ION × 15 MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 28 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
2 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain B； UniProt 2–380 Mutation：H353N Non-standard monomer：Yes (specific site not provided by mmCIF) CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN) × 1 （P00968） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
3 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain H； UniProt 2–380 Mutation：H353N Non-standard monomer：Yes (specific site not provided by mmCIF) CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN) × 1 （P00968） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
4 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain D； UniProt 2–380 Mutation：H353N Non-standard monomer：Yes (specific site not provided by mmCIF) CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN) × 1 （P00968） PO4 PHOSPHATE ION × 4 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å
5 Protein heterocomplex Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain F； UniProt 2–380 Mutation：H353N Non-standard monomer：Yes (specific site not provided by mmCIF) CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN) × 1 （P00968） PO4 PHOSPHATE ION × 3 MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION X-ray crystallization conditions：pH 7.4；0.65M NET4CL 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 THEN SOAKED INTO: 1.4M NET4CL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 5MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL Resolution 1.80 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 1A9X Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Mutation：C269S Mutation：C269S Mutation：C269S Mutation：C269S MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 16 PO4 PHOSPHATE ION × 6 ORN L-ornithine × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain H 1–382（382 aa）
Mutation：C269S MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 1–382（382 aa）
Mutation：C269S MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 1 ORN L-ornithine × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain D 1–382（382 aa）
Mutation：C269S MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C30 CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S Deposited 1999-07-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 1–382（382 aa）
Mutation：C269S MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 4 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, POTASSIUM CHLORIDE, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, L-ORNITHINE, ADP, BERYLLIUM FLUORIDE, HEPPS, pH 7.4, BATCH, temperature 277.0K
Resolution 2.00 Å R-free 0.246
1C3O CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE Deposited 1999-07-28 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Mutation：C269S Mutation：C269S Mutation：C269S Mutation：C269S MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 16 PO4 PHOSPHATE ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 GLN GLUTAMINE × 8 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；278 K；PEG-8000, MANGANESE CHLORIDE, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, BERYLLIUM FLUORIDE, ADENOSINE 5'-DIPHOSPHATE,L-ORNITHINE, L-GLUTAMINE, HEPPS, pH 7.4, BATCH, temperature 278K
Resolution 2.10 Å R-free 0.258
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 12 K POTASSIUM ION × 33 CL CHLORIDE ION × 29 PO4 PHOSPHATE ION × 5 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain D 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain H 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 8 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1CS0 Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Deposited 1999-08-16 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 9 CL CHLORIDE ION × 7 PO4 PHOSPHATE ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions BATCH；pH 7.4；277 K；PEG 8000, TETRAETHYLAMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MANGANESE(II) CHLORIDE, ADENOSINE 5'-DIPHOSPHATE, L-ORNITHINE, L-GLUTAMATE GAMMA-SEMIALDEHYDE, pH 7.4, BATCH, temperature 277K
Resolution 2.00 Å R-free 0.242
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain C 1–382（382 aa）
Chain F 1–382（382 aa）
Chain I 1–382（382 aa）
Chain L 1–382（382 aa）
Not recorded MN MANGANESE (II) ION × 16 K POTASSIUM ION × 29 PO4 PHOSPHATE ION × 9 CL CHLORIDE ION × 29 GLN GLUTAMINE × 8 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 1–382（382 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 7 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 1–382（382 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 6 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain L 1–382（382 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 8 PO4 PHOSPHATE ION × 3 CL CHLORIDE ION × 7 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1JDB CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI Deposited 1997-03-25 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 1–382（382 aa）
Not recorded MN MANGANESE (II) ION × 4 K POTASSIUM ION × 8 PO4 PHOSPHATE ION × 2 CL CHLORIDE ION × 8 GLN GLUTAMINE × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；0.65M TETRAETHYL AMMONIUM CHLORIDE (E4NCL) 8% PEG 8000 100MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM HEPES PH 7.4. THE CRYSTAL WAS SOAKED INTO: 1.4M E4NCL 8% PEG 8000 250MM KCL 2.5MM MNCL2 2.5MM ADP 2.5MM ORNITHINE 25MM GLUTAMINE 25MM HEPES PH 7.4 7.5% ETHYLENE GLYCOL.
Resolution 2.10 Å
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 12 K POTASSIUM ION × 32 CL CHLORIDE ION × 22 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain H 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 5 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain F 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 5 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain B 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 6 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1KEE Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin Deposited 2001-11-15 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric
Chain D 1–382（382 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) MN MANGANESE (II) ION × 3 K POTASSIUM ION × 8 CL CHLORIDE ION × 6 PO4 PHOSPHATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 2 ORN L-ornithine × 1 NET TETRAETHYLAMMONIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, Hepes, potassium chloride, manganese chloride, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.211
1M6V Crystal Structure of the G359F (small subunit) Point Mutant of Carbamoyl Phosphate Synthetase Deposited 2002-07-17 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Mutation：G359F Mutation：G359F Mutation：G359F Mutation：G359F MN MANGANESE (II) ION × 12 K POTASSIUM ION × 26 CL CHLORIDE ION × 28 PO4 PHOSPHATE ION × 4 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG-8000, manganese chloride, potassium chloride, ADP, ornithine, tetraethylammonium chloride, HEPPS, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.245
1T36 Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate Deposited 2004-04-24 Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric
Chain B 1–382（382 aa）
Chain D 1–382（382 aa）
Chain F 1–382（382 aa）
Chain H 1–382（382 aa）
Mutation：C248D Mutation：C248D Mutation：C248D Mutation：C248D MN MANGANESE (II) ION × 12 K POTASSIUM ION × 22 PO4 PHOSPHATE ION × 5 CL CHLORIDE ION × 27 ADP ADENOSINE-5'-DIPHOSPHATE × 8 ORN L-ornithine × 4 NET TETRAETHYLAMMONIUM ION × 4 U5P URIDINE-5'-MONOPHOSPHATE × 4 X-RAY DIFFRACTION
X-ray crystallization conditions batch；pH 7.4；277 K；PEG 8000, tetramethylammonium chloride, potassium chloride, manganese chloride, ornithine, ADP, HEPES, pH 7.4, batch, temperature 277K
Resolution 2.10 Å R-free 0.209

7 other PDB entries and 23 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name CARA_ECOLI
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–379； UniProt 2–380 Author chain D； PDBConstruct 1–379； UniProt 2–380 Author chain F； PDBConstruct 1–379； UniProt 2–380 Author chain H； PDBConstruct 1–379； UniProt 2–380

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 1a9x

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 1a9x
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2. Structure Basics 2. Structure Basics

Entry ID entry_id1a9x
Deposition date deposition_date1998-04-14
Structure title titleCARBAMOYL PHOSPHATE SYNTHETASE: CAUGHT IN THE ACT OF GLUTAMINE HYDROLYSIS
Keywords keywordsAMIDOTRANSFERASE, THIOESTER; AMIDOTRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier72.25 Å
Radius of gyration Rg (electron density) rg_electron72.31 Å
Forward intensity I(0) i05801610000.00
Molecular weight molecular_weight638650.0 kDa
Excluded volume excluded_volume795920 ų
Envelope volume envelope_volume1145400 ų
Hydration-shell volume shell_volume131300 ų
Envelope diameter envelope_diameter240.0 Å
Shell Rg shell_rg75.61 Å
Envelope Rg envelope_rg68.66 Å
Shape Rg shape_rg72.34 Å
Total Rg total_rg72.23 Å
Total atoms total_atoms44683
Residues n_residues5744
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax258.1 Å
Rg (real space) rg_real72.31 Å
Rg uncertainty (real space) rg_real_error2.96 Å
I(0) (real space) i0_real5.8020e+09
I(0) uncertainty (real space) i0_real_error1.3660e+08
Rg (reciprocal space) rg_reciprocal71.91 Å
I(0) (reciprocal space) i0_reciprocal5796000000.0000
Solution quality estimate total_estimate0.8572
Solution quality rating solution_quality GOOD a GOOD solution
P(r) peaks n_peaks2
Primary peak position r_peak_primary93.8 Å
Skewness Skewness skewness0.243
Kurtosis Kurtosis kurtosis-0.574
Angular range angular_range— – 0.1100 Å−1
Current regularization parameter α current_alpha0.0009
Highest regularization parameter α highest_alpha202800000.0000
Real-space data points n_real_points23
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.790; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.770
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (10)

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7. Fold Classification (SCOP + CATH) 72 domains

SCOP 2.08 (32 domains)

Domain ID domain_idd1a9xa1
Class classa — All alpha proteins
Fold Fold folda.92 — Carbamoyl phosphate synthetase, large subunit connection domain
Superfamily Superfamily superfamilya.92.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Family Family familya.92.1.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Domain ID domain_idd1a9xa2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.24 — Methylglyoxal synthase-like
Superfamily Superfamily superfamilyc.24.1 — Methylglyoxal synthase-like
Family Family familyc.24.1.1 — Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
Domain ID domain_idd1a9xa3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xa4
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xa5
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xa6
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xb1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.8 — The 'swivelling' beta/beta/alpha domain
Superfamily Superfamily superfamilyc.8.3 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Family Family familyc.8.3.1 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Domain ID domain_idd1a9xb2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.23 — Flavodoxin-like
Superfamily Superfamily superfamilyc.23.16 — Class I glutamine amidotransferase-like
Family Family familyc.23.16.1 — Class I glutamine amidotransferases (GAT)
Domain ID domain_idd1a9xc1
Class classa — All alpha proteins
Fold Fold folda.92 — Carbamoyl phosphate synthetase, large subunit connection domain
Superfamily Superfamily superfamilya.92.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Family Family familya.92.1.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Domain ID domain_idd1a9xc2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.24 — Methylglyoxal synthase-like
Superfamily Superfamily superfamilyc.24.1 — Methylglyoxal synthase-like
Family Family familyc.24.1.1 — Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
Domain ID domain_idd1a9xc3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xc4
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xc5
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xc6
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xd1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.8 — The 'swivelling' beta/beta/alpha domain
Superfamily Superfamily superfamilyc.8.3 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Family Family familyc.8.3.1 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Domain ID domain_idd1a9xd2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.23 — Flavodoxin-like
Superfamily Superfamily superfamilyc.23.16 — Class I glutamine amidotransferase-like
Family Family familyc.23.16.1 — Class I glutamine amidotransferases (GAT)
Domain ID domain_idd1a9xe1
Class classa — All alpha proteins
Fold Fold folda.92 — Carbamoyl phosphate synthetase, large subunit connection domain
Superfamily Superfamily superfamilya.92.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Family Family familya.92.1.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Domain ID domain_idd1a9xe2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.24 — Methylglyoxal synthase-like
Superfamily Superfamily superfamilyc.24.1 — Methylglyoxal synthase-like
Family Family familyc.24.1.1 — Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
Domain ID domain_idd1a9xe3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xe4
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xe5
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xe6
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xf1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.8 — The 'swivelling' beta/beta/alpha domain
Superfamily Superfamily superfamilyc.8.3 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Family Family familyc.8.3.1 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Domain ID domain_idd1a9xf2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.23 — Flavodoxin-like
Superfamily Superfamily superfamilyc.23.16 — Class I glutamine amidotransferase-like
Family Family familyc.23.16.1 — Class I glutamine amidotransferases (GAT)
Domain ID domain_idd1a9xg1
Class classa — All alpha proteins
Fold Fold folda.92 — Carbamoyl phosphate synthetase, large subunit connection domain
Superfamily Superfamily superfamilya.92.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Family Family familya.92.1.1 — Carbamoyl phosphate synthetase, large subunit connection domain
Domain ID domain_idd1a9xg2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.24 — Methylglyoxal synthase-like
Superfamily Superfamily superfamilyc.24.1 — Methylglyoxal synthase-like
Family Family familyc.24.1.1 — Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
Domain ID domain_idd1a9xg3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xg4
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.30 — PreATP-grasp domain
Superfamily Superfamily superfamilyc.30.1 — PreATP-grasp domain
Family Family familyc.30.1.1 — BC N-terminal domain-like
Domain ID domain_idd1a9xg5
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xg6
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.142 — ATP-grasp
Superfamily Superfamily superfamilyd.142.1 — Glutathione synthetase ATP-binding domain-like
Family Family familyd.142.1.2 — BC ATP-binding domain-like
Domain ID domain_idd1a9xh1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.8 — The 'swivelling' beta/beta/alpha domain
Superfamily Superfamily superfamilyc.8.3 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Family Family familyc.8.3.1 — Carbamoyl phosphate synthetase, small subunit N-terminal domain
Domain ID domain_idd1a9xh2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.23 — Flavodoxin-like
Superfamily Superfamily superfamilyc.23.16 — Class I glutamine amidotransferase-like
Family Family familyc.23.16.1 — Class I glutamine amidotransferases (GAT)

CATH v4.4 (40 domains)

Domain ID domain_id1a9xA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xA03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xA04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1030 — Carbamoyl Phosphate Synthetase; Chain A, domain 4
Homologous superfamily homologous superfamily10 — Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
Domain ID domain_id1a9xA05
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xA06
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xA07
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xA08
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1380 — Methylglyoxal synthase-like domain
Domain ID domain_id1a9xB01
Class class3 — Alpha Beta
Architecture architecture50 — 3-Layer(bba) Sandwich
Topology topology30 — Glucose Oxidase; domain 1
Homologous superfamily homologous superfamily20 — Carbamoyl-phosphate synthase small subunit, N-terminal domain
Domain ID domain_id1a9xB02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
Domain ID domain_id1a9xC01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xC02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xC03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xC04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1030 — Carbamoyl Phosphate Synthetase; Chain A, domain 4
Homologous superfamily homologous superfamily10 — Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
Domain ID domain_id1a9xC05
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xC06
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xC07
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xC08
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1380 — Methylglyoxal synthase-like domain
Domain ID domain_id1a9xD01
Class class3 — Alpha Beta
Architecture architecture50 — 3-Layer(bba) Sandwich
Topology topology30 — Glucose Oxidase; domain 1
Homologous superfamily homologous superfamily20 — Carbamoyl-phosphate synthase small subunit, N-terminal domain
Domain ID domain_id1a9xD02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
Domain ID domain_id1a9xE01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xE02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xE03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xE04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1030 — Carbamoyl Phosphate Synthetase; Chain A, domain 4
Homologous superfamily homologous superfamily10 — Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
Domain ID domain_id1a9xE05
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xE06
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xE07
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xE08
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1380 — Methylglyoxal synthase-like domain
Domain ID domain_id1a9xF01
Class class3 — Alpha Beta
Architecture architecture50 — 3-Layer(bba) Sandwich
Topology topology30 — Glucose Oxidase; domain 1
Homologous superfamily homologous superfamily20 — Carbamoyl-phosphate synthase small subunit, N-terminal domain
Domain ID domain_id1a9xF02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
Domain ID domain_id1a9xG01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xG02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xG03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xG04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1030 — Carbamoyl Phosphate Synthetase; Chain A, domain 4
Homologous superfamily homologous superfamily10 — Carbamoyl-phosphate synthetase, large subunit oligomerisation domain
Domain ID domain_id1a9xG05
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily20 —
Domain ID domain_id1a9xG06
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology470 — D-amino Acid Aminotransferase; Chain A, domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, B domain
Domain ID domain_id1a9xG07
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily20 — ATP-grasp fold, A domain
Domain ID domain_id1a9xG08
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1380 — Methylglyoxal synthase-like domain
Domain ID domain_id1a9xH01
Class class3 — Alpha Beta
Architecture architecture50 — 3-Layer(bba) Sandwich
Topology topology30 — Glucose Oxidase; domain 1
Homologous superfamily homologous superfamily20 — Carbamoyl-phosphate synthase small subunit, N-terminal domain
Domain ID domain_id1a9xH02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily880 — Class I glutamine amidotransferase (GATase) domain
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8. Citations (1)

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9. Files and Curves (10)