← Back to search

1d7p

Crystal structure of the c2 domain of human factor viii at 1.5 a resolution at 1.5 A

Method: X-RAY DIFFRACTION D_max: 54.7 Å Quality: GOOD

SAXS Profile

P(r) Distribution

▼

1. Structure Basics

entry_id	1d7p
deposition_date	1999-10-19
title	Crystal structure of the c2 domain of human factor viii at 1.5 a resolution at 1.5 A
keywords	BETA SANDWICH, BLOOD CLOTTING; BLOOD CLOTTING
method	X-RAY DIFFRACTION

▼

Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

▼

2. SAXS Parameters (CRYSOL)

rg_guinier	16.27 Å
rg_electron	15.09 Å
i0	6685220.00
molecular_weight	18450.0 kDa
excluded_volume	22948 Å³
envelope_volume	25312 Å³
shell_volume	14104 Å³
envelope_diameter	53.8 Å
shell_rg	21.14 Å
envelope_rg	15.58 Å
shape_rg	15.03 Å
total_rg	16.34 Å
total_atoms	1291
n_residues	159
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

▼

3. P(r) Analysis (GNOM)

dmax	54.7 Å
rg_real	16.16 Å
rg_real_error	0.34 Å
i0_real	6.6850e+06
i0_real_error	7.9720e+04
rg_reciprocal	16.17 Å
i0_reciprocal	6685000.0000
total_estimate	0.8690
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	21.0 Å
skewness	0.177
kurtosis	-0.285
angular_range	— – 0.4900 Å⁻¹
current_alpha	0.0000
highest_alpha	1254000.0000
n_real_points	79
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.768; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.998; Smooth: 0.991

▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (5)

Entity 1 polymer

description	COAGULATION FACTOR VIII PRECURSOR
formula_weight	18058.7 kDa
mutation	S2296C
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	M
atom_count	1538

LNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNCLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQ

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Saccharomyces cerevisiae

Entity 2 non-polymer

description	SULFATE ION
formula_weight	96.1 kDa
src_method	syn
entity_count	2

Entity 3 non-polymer

description	CYSTEINE
formula_weight	121.2 kDa
src_method	syn
entity_count	1

Entity 4 non-polymer

description	GLYCEROL
formula_weight	92.1 kDa
src_method	syn
entity_count	1

Entity 5 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	247

▶

6. Citations (1)

▶

length_a	46.440 Å
length_b	56.410 Å
length_c	65.740 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	1.500 Å
resolution_low	50.000 Å
r_factor	0.2060
r_work	0.2050
r_free	0.2150

fit	/app/data/saxs_computation/d7/1d7p/1d7p.fit
pddf	/app/data/pr_computation/d7/1d7p/1d7p.pr.out
profile	/app/data/saxs_computation/d7/1d7p/1d7p.dat