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1dhs

CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE

Method: X-RAY DIFFRACTION D_max: 92.2 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1dhs
deposition_date	1997-10-28
title	CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE
keywords	SPERMIDINE, INITIATION FACTOR 5A, NAD, SUBUNIT INTERACTIONS, OXIDOREDUCTASE, TRANSFERASE; TRANSFERASE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	23.56 Å
rg_electron	22.82 Å
i0	25961400.00
molecular_weight	38716.0 kDa
excluded_volume	48381 Å³
envelope_volume	61358 Å³
shell_volume	23121 Å³
envelope_diameter	96.7 Å
shell_rg	29.02 Å
envelope_rg	24.42 Å
shape_rg	22.82 Å
total_rg	23.61 Å
total_atoms	2721
n_residues	344
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	92.2 Å
rg_real	23.71 Å
rg_real_error	0.95 Å
i0_real	2.5960e+07
i0_real_error	4.0220e+05
rg_reciprocal	23.67 Å
i0_reciprocal	25960000.0000
total_estimate	0.5766
solution_quality	REASONABLE a REASONABLE solution
n_peaks	2
r_peak_primary	27.4 Å
skewness	0.653
kurtosis	0.584
angular_range	— – 0.3350 Å⁻¹
current_alpha	0.0000
highest_alpha	3025000.0000
n_real_points	65
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.471; Stabil: 1.000; Sysdev: 0.154; Positv: 1.000; Valcen: 0.733; Smooth: 0.884

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	DEOXYHYPUSINE SYNTHASE
formula_weight	40079.4 kDa
ec_number	2.5.1.46
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	2988

APAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLVQHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMDAFMHEKNED

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli BL21(DE3)

Entity 2 non-polymer

description	NICOTINAMIDE-ADENINE-DINUCLEOTIDE
formula_weight	663.4 kDa
src_method	syn
entity_count	1

Entity 3 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	267

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6. Citations (1)

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length_a	108.300 Å
length_b	108.300 Å
length_c	69.500 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 4 21 2
int_tables_number	90
crystal_system	—

resolution	2.200 Å
resolution_low	6.000 Å
r_factor	0.1530
r_work	0.1530
r_free	0.2420

fit	/app/data/saxs_computation/dh/1dhs/1dhs.fit
pddf	/app/data/pr_computation/dh/1dhs/1dhs.pr.out
profile	/app/data/saxs_computation/dh/1dhs/1dhs.dat

CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction