1dre
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 1dre |
| deposition_date | 1996-11-28 |
| title | DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) |
| keywords | OXIDOREDUCTASE, NADP, TRIMETHOPRIM RESISTANCE, METHOTREXATE RESISTANCE, ONE-CARBON METABOLISM; OXIDOREDUCTASE |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 16.46 Å |
| rg_electron | 15.14 Å |
| i0 | 7422490.00 |
| molecular_weight | 19187.0 kDa |
| excluded_volume | 23598 ų |
| envelope_volume | 25904 ų |
| shell_volume | 14370 ų |
| envelope_diameter | 50.7 Å |
| shell_rg | 21.14 Å |
| envelope_rg | 15.46 Å |
| shape_rg | 15.14 Å |
| total_rg | 16.13 Å |
| total_atoms | 1349 |
| n_residues | 159 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 51.8 Å |
| rg_real | 16.34 Å |
| rg_real_error | 0.31 Å |
| i0_real | 7.4220e+06 |
| i0_real_error | 8.4740e+04 |
| rg_reciprocal | 16.35 Å |
| i0_reciprocal | 7423000.0000 |
| total_estimate | 0.8931 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 21.9 Å |
| skewness | 0.126 |
| kurtosis | -0.420 |
| angular_range | — – 0.4850 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 1554000.0000 |
| n_real_points | 79 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.876; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.989; Smooth: 0.991 |