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1f42

THE P40 DOMAIN OF HUMAN INTERLEUKIN-12

Method: X-RAY DIFFRACTION D_max: 101.3 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	1f42
deposition_date	2000-06-07
title	THE P40 DOMAIN OF HUMAN INTERLEUKIN-12
keywords	Cytokine; CYTOKINE
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	27.23 Å
rg_electron	27.15 Å
i0	20818800.00
molecular_weight	34144.0 kDa
excluded_volume	42402 Å³
envelope_volume	57999 Å³
shell_volume	20113 Å³
envelope_diameter	106.8 Å
shell_rg	30.83 Å
envelope_rg	27.55 Å
shape_rg	27.09 Å
total_rg	27.79 Å
total_atoms	2401
n_residues	297
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	101.3 Å
rg_real	27.64 Å
rg_real_error	1.24 Å
i0_real	2.0820e+07
i0_real_error	3.6790e+05
rg_reciprocal	27.51 Å
i0_reciprocal	20820000.0000
total_estimate	0.5806
solution_quality	REASONABLE a REASONABLE solution
n_peaks	2
r_peak_primary	24.5 Å
skewness	0.627
kurtosis	-0.098
angular_range	— – 0.2900 Å⁻¹
current_alpha	0.0000
highest_alpha	3573000.0000
n_real_points	59
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.598; Stabil: 1.000; Sysdev: 0.127; Positv: 1.000; Valcen: 0.475; Smooth: 0.894

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	INTERLEUKIN-12 BETA CHAIN
formula_weight	34739.9 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	2456

IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Cricetulus griseus

Entity 2 branched

description	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
formula_weight	586.5 kDa
src_method	man
entity_count	1

Entity 3 non-polymer

description	5-MERCAPTO-2-NITRO-BENZOIC ACID
formula_weight	199.2 kDa
src_method	syn
entity_count	2

Entity 4 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	55

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6. Citations (1)

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length_a	34.000 Å
length_b	55.000 Å
length_c	189.200 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	4

space_group	P 21 21 21
int_tables_number	19
crystal_system	—

resolution	2.500 Å
resolution_low	15.000 Å
r_factor	0.2810
r_work	0.2270
r_free	0.2810

fit	/app/data/saxs_computation/f4/1f42/1f42.fit
pddf	/app/data/pr_computation/f4/1f42/1f42.pr.out
profile	/app/data/saxs_computation/f4/1f42/1f42.dat

THE P40 DOMAIN OF HUMAN INTERLEUKIN-12

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction