1fg9

3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER

Method: X-RAY DIFFRACTION D_max: 131.4 Å Quality: REASONABLE

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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1. 结构基本信息 1. Structure Basics

条目编号 entry_id	1fg9
沉积日期 deposition_date	2000-07-28
结构标题 title	3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER
关键词 keywords	cytokine-receptor complex, fibronectin type-III, IMMUNE SYSTEM; IMMUNE SYSTEM
实验方法 method	X-RAY DIFFRACTION

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2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	38.18 Å
回转半径 Rg (电子) rg_electron	38.29 Å
零角强度 I(0) i0	149701000.00
分子量 molecular_weight	98251.0 kDa
排除体积 excluded_volume	122900 Å³
包络体积 envelope_volume	173250 Å³
水化壳体积 shell_volume	40548 Å³
包络直径 envelope_diameter	141.5 Å
壳层 Rg shell_rg	40.50 Å
包络 Rg envelope_rg	38.18 Å
形状 Rg shape_rg	38.28 Å
总 Rg total_rg	38.50 Å
总原子数 total_atoms	6905
残基数 n_residues	862
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	131.4 Å
Rg (实空间) rg_real	38.39 Å
Rg 误差 (实空间) rg_real_error	1.33 Å
I(0) (实空间) i0_real	1.4970e+08
I(0) 误差 (实空间) i0_real_error	2.6880e+06
Rg (倒空间) rg_reciprocal	38.26 Å
I(0) (倒空间) i0_reciprocal	149700000.0000
解质量估计 total_estimate	0.6438
解质量评级 solution_quality	REASONABLE a REASONABLE solution
P(r) 峰数 n_peaks	2
主峰位置 r_peak_primary	48.1 Å
偏度 Skewness skewness	0.432
峰度 Kurtosis kurtosis	-0.213
角度范围 angular_range	— – 0.2050 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	11130000.0000
实空间数据点数 n_real_points	42
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.854; Stabil: 1.000; Sysdev: 0.035; Positv: 1.000; Valcen: 0.932; Smooth: 0.764

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合体信息 (2)

Entity 1 polymer

描述 description	INTERFERON GAMMA
分子量 formula_weight	15730.9 kDa
来源方法 src_method	man
拷贝数 entity_count	2

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	A,B
原子数 atom_count	6905

MQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQ

来源 Source

来源生物 organism	Homo sapiens
通用名 common_name	human
NCBI 分类编号 ncbi_taxonomy_id	9606
宿主生物 host_organism	Escherichia coli

Entity 2 polymer

描述 description	INTERFERON-GAMMA RECEPTOR ALPHA CHAIN
分子量 formula_weight	27649.4 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合体 Polymer

聚合体类型 type	polypeptide(L)
链编号 strand_id	C,D,E

EMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLS

来源 Source

来源生物 organism	Homo sapiens
通用名 common_name	human
NCBI 分类编号 ncbi_taxonomy_id	9606
宿主生物 host_organism	unidentified baculovirus

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6. 折叠分类 (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

结构域编号 domain_id	d1fg9a_
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.26 — 4-helical cytokines
超家族 Superfamily superfamily	a.26.1 — 4-helical cytokines
家族 Family family	a.26.1.3 — Interferons/interleukin-10 (IL-10)

结构域编号 domain_id	d1fg9b_
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.26 — 4-helical cytokines
超家族 Superfamily superfamily	a.26.1 — 4-helical cytokines
家族 Family family	a.26.1.3 — Interferons/interleukin-10 (IL-10)

结构域编号 domain_id	d1fg9c1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

结构域编号 domain_id	d1fg9c2
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

结构域编号 domain_id	d1fg9d1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

结构域编号 domain_id	d1fg9d2
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

结构域编号 domain_id	d1fg9e1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

结构域编号 domain_id	d1fg9e2
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.1 — Immunoglobulin-like beta-sandwich
超家族 Superfamily superfamily	b.1.2 — Fibronectin type III
家族 Family family	b.1.2.1 — Fibronectin type III

CATH v4.4 (8 domains)

结构域编号 domain_id	1fg9A00
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1250 — Growth Hormone; Chain: A;
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	1fg9B00
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1250 — Growth Hormone; Chain: A;
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	1fg9C01
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

结构域编号 domain_id	1fg9C02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

结构域编号 domain_id	1fg9D01
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

结构域编号 domain_id	1fg9D02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

结构域编号 domain_id	1fg9E01
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

结构域编号 domain_id	1fg9E02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily	10 — Immunoglobulins

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7. 引用文献 (1)

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晶胞边长 a length_a	199.300 Å
晶胞边长 b length_b	114.650 Å
晶胞边长 c length_c	74.340 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	116.27 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	12

空间群 space_group	C 1 2 1
空间群编号 int_tables_number	5
晶系 crystal_system	—

分辨率 resolution	2.900 Å
最低分辨率 resolution_low	6.000 Å
R 因子 r_factor	—
R_work r_work	0.2370
R_free r_free	0.3020

fit	/app/data/saxs_computation/fg/1fg9/1fg9.fit
pddf	/app/data/pr_computation/fg/1fg9/1fg9.pr.out
profile	/app/data/saxs_computation/fg/1fg9/1fg9.dat

3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

1. 结构基本信息 1. Structure Basics

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

5. 实体与聚合体信息 (2)

Entity 1 polymer

聚合体 Polymer

来源 Source

Entity 2 polymer

聚合体 Polymer

来源 Source

6. 折叠分类 (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

CATH v4.4 (8 domains)

7. 引用文献 (1)

8. 文件与曲线 (10)

Files (7)

Curves (3)