← Back to search
1hwy

BOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

GLUTAMATE DEHYDROGENASE

OrganismNot specified

UniProt P00366

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 PHOSPHATE ION × 24 2-OXOGLUTARIC ACID × 6 NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 12 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
1hwy 1nqt 1nqt 1nqt 1nr7 1nr7 1nr7 3jcz 3jd0 3jd1 3jd2 3jd3

16 assemblies; showing the first 12

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name DHE3_BOVIN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–501； UniProt 1–501 Author chain B； PDBConstruct 1–501； UniProt 1–501 Author chain C； PDBConstruct 1–501； UniProt 1–501 Author chain D； PDBConstruct 1–501； UniProt 1–501 Author chain E； PDBConstruct 1–501； UniProt 1–501 Author chain F； PDBConstruct 1–501； UniProt 1–501

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1hwy
Deposition date deposition_date2001-01-10
Structure title titleBOVINE GLUTAMATE DEHYDROGENASE COMPLEXED WITH NAD AND 2-OXOGLUTARATE
Keywords keywordsallostery, glutamate dehydrogenase, NAD, OXIDOREDUCTASE; OXIDOREDUCTASE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1hwy__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1hwy__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1hwy__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）42.84 Å
Rg (electron density)42.48 Å
Total Rg42.86 Å
Atom count24168
Residues3006
Excluded volume426280 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1hwy__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (5)

▼

6. Fold Classification (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

Domain ID domain_idd1hwya1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwya2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases
Domain ID domain_idd1hwyb1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwyb2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases
Domain ID domain_idd1hwyc1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwyc2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases
Domain ID domain_idd1hwyd1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwyd2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases
Domain ID domain_idd1hwye1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwye2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases
Domain ID domain_idd1hwyf1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1hwyf2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.1 — Aminoacid dehydrogenases

CATH v4.4 (18 domains)

Domain ID domain_id1hwyA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyA02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyA03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1hwyB01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyB02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyB03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1hwyC01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyC02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyC03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1hwyD01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyD02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyD03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1hwyE01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyE02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyE03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1hwyF01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily140 —
Domain ID domain_id1hwyF02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10860 — Leucine Dehydrogenase, chain A, domain 1
Domain ID domain_id1hwyF03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
▶

7. Citations (3)