Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | IL-4 RECEPTOR PHOSPHOPEPTIDE × 1 （P24394） | Consistent with protein count |
| UniProt name | IRS1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 2–112； UniProt 157–267 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | IRS-1 × 1 （P35568） | Consistent with protein count |
| UniProt name | IL4RA_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 1–11； UniProt 489–499 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1irs |
| Deposition date deposition_date | 1996-03-22 |
| Structure title title | IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE |
| Keywords keywords | ;PHOSPHOTYROSINE BINDING DOMAIN (PTB), COMPLEX, SIGNAL TRANSDUCTION, COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE), COMPLEX (SIGNAL TRANSDUCTION-PEPTIDE) complex ;; COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) |
| Experimental Method method | SOLUTION NMR |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 15.46 Å |
| Rg (electron density) | 13.93 Å |
| Total Rg | 15.22 Å |
| Atom count | 1956 |
| Residues | 122 |
| Excluded volume | 17418 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1irsa1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.55 — PH domain-like barrel |
| Superfamily Superfamily superfamily | b.55.1 — PH domain-like |
| Family Family family | b.55.1.2 — Phosphotyrosine-binding domain (PTB) |
| Domain ID domain_id | d1irsa2 |
| Class class | l — Artifacts |
| Fold Fold fold | l.1 — Tags |
| Superfamily Superfamily superfamily | l.1.1 — Tags |
| Family Family family | l.1.1.1 — Tags |
| Domain ID domain_id | 1irsA00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 30 — Roll |
| Topology topology | 29 — PH-domain like |
| Homologous superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |