Escherichia coli
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein homooligomer | Homooligomer | Protein 3 | No other associated polymer | Consistent with protein count |
| UniProt name | ACRB_ECOLI |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–1049； UniProt 1–1049 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1iwg |
| Deposition date deposition_date | 2002-05-15 |
| Structure title title | Crystal structure of Bacterial Multidrug Efflux transporter AcrB |
| Keywords keywords | Drug resistance, multidrug efflux, transporter, antiporter, membrane protein; MEMBRANE PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 45.51 Å |
| Rg (electron density) | 44.92 Å |
| Total Rg | 45.23 Å |
| Atom count | 22917 |
| Residues | 3018 |
| Excluded volume | 414290 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1iwga1 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.58 — Ferredoxin-like |
| Superfamily Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Family Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Domain ID domain_id | d1iwga2 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.58 — Ferredoxin-like |
| Superfamily Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Family Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Domain ID domain_id | d1iwga3 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.58 — Ferredoxin-like |
| Superfamily Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Family Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Domain ID domain_id | d1iwga4 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.58 — Ferredoxin-like |
| Superfamily Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Family Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| Domain ID domain_id | d1iwga5 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.225 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Superfamily Superfamily superfamily | d.225.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Family Family family | d.225.1.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Domain ID domain_id | d1iwga6 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.225 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Superfamily Superfamily superfamily | d.225.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Family Family family | d.225.1.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Domain ID domain_id | d1iwga7 |
| Class class | f — Membrane and cell surface proteins and peptides |
| Fold Fold fold | f.35 — Multidrug efflux transporter AcrB transmembrane domain |
| Superfamily Superfamily superfamily | f.35.1 — Multidrug efflux transporter AcrB transmembrane domain |
| Family Family family | f.35.1.1 — Multidrug efflux transporter AcrB transmembrane domain |
| Domain ID domain_id | d1iwga8 |
| Class class | f — Membrane and cell surface proteins and peptides |
| Fold Fold fold | f.35 — Multidrug efflux transporter AcrB transmembrane domain |
| Superfamily Superfamily superfamily | f.35.1 — Multidrug efflux transporter AcrB transmembrane domain |
| Family Family family | f.35.1.1 — Multidrug efflux transporter AcrB transmembrane domain |
| Domain ID domain_id | 1iwgA01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1640 — Multidrug efflux transporter AcrB transmembrane fold |
| Homologous superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB transmembrane domain |
| Domain ID domain_id | 1iwgA02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 1430 — Multidrug efflux transporter AcrB pore domain |
| Domain ID domain_id | 1iwgA03 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 1320 — Multidrug efflux transporter AcrB pore domain like |
| Domain ID domain_id | 1iwgA04 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Homologous superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Domain ID domain_id | 1iwgA05 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1640 — Multidrug efflux transporter AcrB transmembrane fold |
| Homologous superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB transmembrane domain |
| Domain ID domain_id | 1iwgA06 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 1430 — Multidrug efflux transporter AcrB pore domain |
| Domain ID domain_id | 1iwgA07 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 70 — Alpha-Beta Plaits |
| Homologous superfamily homologous superfamily | 1440 — Multidrug efflux transporter AcrB pore domain |
| Domain ID domain_id | 1iwgA08 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| Homologous superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |