AcrB
Escherichia coli
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 3 | 无其他共同聚合物 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | ACRB_ECOLI |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–1049； UniProt 1–1049 |
1iwg
Crystal structure of Bacterial Multidrug Efflux transporter AcrB
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 1iwg |
| 沉积日期 deposition_date | 2002-05-15 |
| 结构标题 title | Crystal structure of Bacterial Multidrug Efflux transporter AcrB |
| 关键词 keywords | Drug resistance, multidrug efflux, transporter, antiporter, membrane protein; MEMBRANE PROTEIN |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
1iwg__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1iwg__assembly_1__model_1 | I(q)
1iwg__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 45.51 Å |
| Rg（电子密度） | 44.92 Å |
| 总 Rg | 45.23 Å |
| 原子数 | 22917 |
| 残基数 | 3018 |
| 排除体积 | 414290 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (1)
6. 折叠分类 (SCOP + CATH) 16 domains
SCOP 2.08 (8 domains)
| 结构域编号 domain_id | d1iwga1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.58 — Ferredoxin-like |
| 超家族 Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 家族 Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 结构域编号 domain_id | d1iwga2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.58 — Ferredoxin-like |
| 超家族 Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 家族 Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 结构域编号 domain_id | d1iwga3 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.58 — Ferredoxin-like |
| 超家族 Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 家族 Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 结构域编号 domain_id | d1iwga4 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.58 — Ferredoxin-like |
| 超家族 Superfamily superfamily | d.58.44 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 家族 Family family | d.58.44.1 — Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 结构域编号 domain_id | d1iwga5 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.225 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 超家族 Superfamily superfamily | d.225.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 家族 Family family | d.225.1.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 结构域编号 domain_id | d1iwga6 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.225 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 超家族 Superfamily superfamily | d.225.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 家族 Family family | d.225.1.1 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 结构域编号 domain_id | d1iwga7 |
| 类 Class class | f — Membrane and cell surface proteins and peptides |
| 折叠类型 Fold fold | f.35 — Multidrug efflux transporter AcrB transmembrane domain |
| 超家族 Superfamily superfamily | f.35.1 — Multidrug efflux transporter AcrB transmembrane domain |
| 家族 Family family | f.35.1.1 — Multidrug efflux transporter AcrB transmembrane domain |
| 结构域编号 domain_id | d1iwga8 |
| 类 Class class | f — Membrane and cell surface proteins and peptides |
| 折叠类型 Fold fold | f.35 — Multidrug efflux transporter AcrB transmembrane domain |
| 超家族 Superfamily superfamily | f.35.1 — Multidrug efflux transporter AcrB transmembrane domain |
| 家族 Family family | f.35.1.1 — Multidrug efflux transporter AcrB transmembrane domain |
CATH v4.4 (8 domains)
| 结构域编号 domain_id | 1iwgA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1640 — Multidrug efflux transporter AcrB transmembrane fold |
| 同源超家族 H-superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB transmembrane domain |
| 结构域编号 domain_id | 1iwgA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 1430 — Multidrug efflux transporter AcrB pore domain |
| 结构域编号 domain_id | 1iwgA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 1320 — Multidrug efflux transporter AcrB pore domain like |
| 结构域编号 domain_id | 1iwgA04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 同源超家族 H-superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 结构域编号 domain_id | 1iwgA05 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1640 — Multidrug efflux transporter AcrB transmembrane fold |
| 同源超家族 H-superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB transmembrane domain |
| 结构域编号 domain_id | 1iwgA06 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 1430 — Multidrug efflux transporter AcrB pore domain |
| 结构域编号 domain_id | 1iwgA07 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 1440 — Multidrug efflux transporter AcrB pore domain |
| 结构域编号 domain_id | 1iwgA08 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 同源超家族 H-superfamily homologous superfamily | 10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |