SAXSdb — 1n9v

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Angiotensin II

OrganismNot specified

State in the Current Structure

Assembly	Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Associated Components	Method and Experimental Conditions	Structure Quality
1	Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count	Chain A； UniProt 34–41	Not recorded	No other associated polymer	SOLUTION NMR NMR measurement conditions：298 K；Pressure ambient NMR sample composition：2.5 mM; DMSO-d6 \| DMSO-d6	Resolution not provided

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB	Difference from Current Entry 1N9V	Assembly / Oligomeric State	Construct	Mutations and Modifications	Ligands, Ions and Non-polymers	Method and Experimental Conditions	Structure Quality
1N9U Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship Deposited 2002-11-26	Different construct	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 34–43（10 aa）	Not recorded	No recorded non-water small molecule	SOLUTION NMR NMR measurement conditions 298 K；Pressure ambient NMR sample composition 2.5 mM; DMSO-d6 \| DMSO-d6	Resolution not provided
2JP8 Angiotensin 1-7 Deposited 2007-04-27	Different construct Different experimental conditions	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain P 34–40（7 aa）	Not recorded	No recorded non-water small molecule	SOLUTION NMR NMR measurement conditions pH 2.9；278 K；Ionic strength (raw mmCIF value) 12；Pressure ambient NMR sample composition 12.0 mM angiotensin, 95% H2O/5% D2O \| 95% H2O/5% D2O	Resolution not provided
2WXW Crystal structure of human angiotensinogen Deposited 2009-11-11	Different construct Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 34–485（452 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions pH 8；2-2.5N NACL, 0.2M CACL2, 0.1M TRIS-HCL, PH8	Resolution 3.30 Å R-free 0.318
2X0B Crystal structure of human angiotensinogen complexed with renin Deposited 2009-12-08	Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric	Chain F 34–485（452 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions pH 6；1.6-2.2M AS, 0.1M MES, PH6	Resolution 4.33 Å R-free 0.334
2X0B Crystal structure of human angiotensinogen complexed with renin Deposited 2009-12-08	Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric	Chain D 34–485（452 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions pH 6；1.6-2.2M AS, 0.1M MES, PH6	Resolution 4.33 Å R-free 0.334
2X0B Crystal structure of human angiotensinogen complexed with renin Deposited 2009-12-08	Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric	Chain B 34–485（452 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions pH 6；1.6-2.2M AS, 0.1M MES, PH6	Resolution 4.33 Å R-free 0.334
2X0B Crystal structure of human angiotensinogen complexed with renin Deposited 2009-12-08	Different construct Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric	Chain H 34–485（452 aa）	Not recorded	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions pH 6；1.6-2.2M AS, 0.1M MES, PH6	Resolution 4.33 Å R-free 0.334
4AA1 Crystal structure of ANCE in complex with Angiotensin-II Deposited 2011-11-30	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric	Chain P 34–41（8 aa）	Not recorded	ZN ZINC ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2	X-RAY DIFFRACTION X-ray crystallization conditions pH 7.5；0.1 M HEPES 7.5, 1.3 M SODIUM CITRATE	Resolution 1.99 Å R-free 0.211
4APH Human angiotensin-converting enzyme in complex with angiotensin-II Deposited 2012-04-03	Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric	Chain P 34–41（8 aa）	Not recorded	CL CHLORIDE ION × 2 ZN ZINC ION × 1 PE4 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 ACT ACETATE ION × 5	X-RAY DIFFRACTION X-ray crystallization conditions pH 4.7；50MM SODIUM ACETATE PH 4.7, 16% PEG4000, 10UM ZNSO4	Resolution 1.99 Å R-free 0.240
4FYS Human aminopeptidase N (CD13) in complex with angiotensin IV Deposited 2012-07-05	Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric	Chain C 36–41（6 aa）	Not recorded	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 SO4 SULFATE ION × 11	X-RAY DIFFRACTION X-ray crystallization conditions hanging drop vapor diffusion；pH 5；295 K；2M ammonium sulfate, 0.1M sodium acetate, 10% glycerol, pH 5.0, hanging drop vapor diffusion, temperature 295K	Resolution 2.01 Å R-free 0.198
5E2Q Structure of human DPP3 in complex with angiotensin-II Deposited 2015-10-01	Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric	Chain B 34–41（8 aa） Fragment：UNP residues 34-41	Not recorded	MG MAGNESIUM ION × 1 K POTASSIUM ION × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；293 K；0.056 M sodium phosphate monobasic monohydrate, 1.344 M potassium phosphate dibasic monohydrate	Resolution 2.40 Å R-free 0.247
5M3X Crystal structure of human angiotensin I-deleted angiotensinogen Deposited 2016-10-17	Different construct Different mutation/modification Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 44–485（442 aa）	Mutation：N137Q, N271Q, N295Q, C232S, C308S	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；1.7M Ammonium Sulfate, 0.1M Citric Acid, pH3.6	Resolution 2.63 Å R-free 0.282
5M3X Crystal structure of human angiotensin I-deleted angiotensinogen Deposited 2016-10-17	Different construct Different mutation/modification Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain B 44–485（442 aa）	Mutation：N137Q, N271Q, N295Q, C232S, C308S	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；1.7M Ammonium Sulfate, 0.1M Citric Acid, pH3.6	Resolution 2.63 Å R-free 0.282
5M3Y Crystal structure of human glycosylated angiotensinogen Deposited 2016-10-17	Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric	Chain A 34–485（452 aa）	Mutation：N137Q, N271Q, N295Q, C232S, C308S	No recorded non-water small molecule	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293.15 K；2.0M Ammonium Sulfate, 0.1M Bicine, pH9.0	Resolution 2.30 Å R-free 0.189
6I3F Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom Deposited 2018-11-06	Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric	Chain A 34–485（452 aa）	Mutation：N137Q, N271Q, N295Q,C232S,C308S	SO4 SULFATE ION × 10 GOL GLYCEROL × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.6；293 K；1.76M Ammonium sulfate 0.1M Tris, pH7.6	Resolution 2.55 Å R-free 0.234
6I3I Crystal structure of reactive center loop (RCL) cleaved angiotensinogen Deposited 2018-11-06	Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric	Chain A 34–485（452 aa）	Mutation：N137Q,N271Q,N295Q,C232S,C308S	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1	X-RAY DIFFRACTION X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；1.5M ammonium sulfate, 0.1M Tris pH8.5 12% glycerol	Resolution 2.97 Å R-free 0.237
6OS0 Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II Deposited 2019-05-01	Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics	Assembly 1 Insufficient information Heteromer；Protein × 3 PDB declaration: trimeric	Chain B 34–41（8 aa） Fragment：residues 34-41	Not recorded	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CL CHLORIDE ION × 2	X-RAY DIFFRACTION X-ray crystallization conditions LIPIDIC CUBIC PHASE；pH 7.6；293 K；Protein complex was reconstituted with a 10:1 (w/w) mixture of monoolein and cholesterol. Crystals were grown in 100 mM Tris pH 7.6, 10 mM MgCl2, 25-26% PEG 300	Resolution 2.90 Å R-free 0.318

13 other PDB entries and 17 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence

UniProt name	ANGT_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–8； UniProt 34–41

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1n9v
Deposition date deposition_date	2002-11-26
Structure title title	Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship.
Keywords keywords	Angiotensin, Renin-Angiotensin System, Solid Phase Peptide Synthesis, NMR Solution Structure, Peptides, SIGNALING PROTEIN; SIGNALING PROTEIN
Experimental Method method	SOLUTION NMR

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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier	6.44 Å
Radius of gyration Rg (electron density) rg_electron	7.06 Å
Forward intensity I(0) i0	6221280.00
Molecular weight molecular_weight	21970.0 kDa
Excluded volume excluded_volume	27952 Å³
Envelope volume envelope_volume	2232 Å³
Hydration-shell volume shell_volume	3017 Å³
Envelope diameter envelope_diameter	25.6 Å
Shell Rg shell_rg	11.41 Å
Envelope Rg envelope_rg	8.22 Å
Shape Rg shape_rg	7.05 Å
Total Rg total_rg	7.37 Å
Total atoms total_atoms	3066
Residues n_residues	168
Spherical-harmonic order n_harmonics	20
q range q_range	— – 0.5000 Å⁻¹
Data points n_points	101
Shell type shell_type	directional
Solvent electron density solvent_density	0.3340 e/Å³
Shell contrast contrast_shell	0.0300 e/Å³
CRYSOL version crysol_version	4.1.3

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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax	24.8 Å
Rg (real space) rg_real	6.48 Å
Rg uncertainty (real space) rg_real_error	0.53 Å
I(0) (real space) i0_real	6.2210e+06
I(0) uncertainty (real space) i0_real_error	7.2040e+04
Rg (reciprocal space) rg_reciprocal	6.48 Å
I(0) (reciprocal space) i0_reciprocal	6221000.0000
Solution quality estimate total_estimate	0.6281
Solution quality rating solution_quality	REASONABLE a REASONABLE solution
P(r) peaks n_peaks	3
Primary peak position r_peak_primary	2.5 Å
Skewness Skewness skewness	0.007
Kurtosis Kurtosis kurtosis	-1.412
Angular range angular_range	— – 0.5000 Å⁻¹
Current regularization parameter α current_alpha	0.0000
Highest regularization parameter α highest_alpha	502.8000
Real-space data points n_real_points	80
GNOM version gnom_version	4.1.3
Quality Criteria quality_criteria	AN1: 0.000; Oscil: 0.046; Stabil: 0.994; Sysdev: 1.000; Positv: 1.000; Valcen: 0.138; Smooth: 0.904

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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (1)

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7. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_id	d1n9va_
Class class	j — Peptides
Fold Fold fold	j.102 — Angiotensin
Superfamily Superfamily superfamily	j.102.1 — Angiotensin
Family Family family	j.102.1.1 — Angiotensin

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8. Citations (2)

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Description description	Angiotensin II
Molecular weight formula_weight	1048.2 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	3066

fit	/app/data/saxs_computation/n9/1n9v/1n9v.fit
pddf	/app/data/pr_computation/n9/1n9v/1n9v.pr.out
profile	/app/data/saxs_computation/n9/1n9v/1n9v.dat

Differences and Similarities in Solution Structures of Angiotensin I & II: Implication for Structure-Function Relationship.

1. Protein Identity and Related Structures Protein Identity & Related Structures

Angiotensin II

State in the Current Structure

Other States of the Same Protein in the Database

SAXS scattering curve SAXS Profile

P(r) Distance Distribution P(r) Distribution

2. Structure Basics 2. Structure Basics

3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

5. Crystallography and Experiment 5. Crystallography & Experiment

6. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

7. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

8. Citations (2)

9. Files and Curves (10)

Files (7)

Curves (3)