1rxu

E. coli uridine phosphorylase: thymidine phosphate complex

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Uridine phosphorylase

Escherichia coli

UniProt P12758

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 6 PHOSPHATE ION × 6 POTASSIUM ION × 3 THYMIDINE × 6 water × 6 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 6 PHOSPHATE ION × 6 POTASSIUM ION × 3 THYMIDINE × 6 water × 6 与蛋白数一致
3 蛋白同源多聚体 同源多聚体 蛋白 6 PHOSPHATE ION × 6 POTASSIUM ION × 3 THYMIDINE × 6 water × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 UDP_ECOLI
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–253; UniProt 0–252 作者链 B; PDB构建体 1–253; UniProt 0–252 作者链 C; PDB构建体 1–253; UniProt 0–252 作者链 D; PDB构建体 1–253; UniProt 0–252 作者链 E; PDB构建体 1–253; UniProt 0–252 作者链 F; PDB构建体 1–253; UniProt 0–252 作者链 G; PDB构建体 1–253; UniProt 0–252 作者链 H; PDB构建体 1–253; UniProt 0–252 作者链 I; PDB构建体 1–253; UniProt 0–252 作者链 J; PDB构建体 1–253; UniProt 0–252 作者链 K; PDB构建体 1–253; UniProt 0–252 作者链 L; PDB构建体 1–253; UniProt 0–252 作者链 M; PDB构建体 1–253; UniProt 0–252 作者链 N; PDB构建体 1–253; UniProt 0–252 作者链 O; PDB构建体 1–253; UniProt 0–252 作者链 P; PDB构建体 1–253; UniProt 0–252 作者链 Q; PDB构建体 1–253; UniProt 0–252 作者链 R; PDB构建体 1–253; UniProt 0–252

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id1rxu
沉积日期 deposition_date2003-12-18
结构标题 titleE. coli uridine phosphorylase: thymidine phosphate complex
关键词 keywordspentosyltransferase, uridine phosphorylase, thymidine, induced fit, specificity, potassium, TRANSFERASE; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1rxu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1rxu__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

1rxu__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)33.68 Å
Rg(电子密度)33.05 Å
总 Rg33.72 Å
原子数11415
残基数1500
排除体积203070 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 1rxu__assembly_1__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 1rxu__assembly_2__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 1rxu__assembly_3__model_1 hexameric (6) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

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6. 折叠分类 (SCOP + CATH) 36 domains

SCOP 2.08 (18 domains)

结构域编号 domain_idd1rxua_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxub_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuc_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxud_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxue_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuf_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxug_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuh_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxui_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuj_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuk_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxul_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxum_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxun_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuo_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxup_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxuq_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases
结构域编号 domain_idd1rxur_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.56 — Phosphorylase/hydrolase-like
超家族 Superfamily superfamilyc.56.2 — Purine and uridine phosphorylases
家族 Family familyc.56.2.1 — Purine and uridine phosphorylases

CATH v4.4 (18 domains)

结构域编号 domain_id1rxuA00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuB00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuC00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuD00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuE00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuF00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuG00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuH00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuI00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuJ00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuK00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuL00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuM00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuN00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuO00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuP00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuQ00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
结构域编号 domain_id1rxuR00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily1580 — Nucleoside phosphorylase domain
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7. 引用文献 (1)