Calmodulin
Homo sapiens
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count | Chain A； UniProt 2–80 | Fragment：N-terminal domain Mutation：N60D | CA CALCIUM ION × 2 | SOLUTION NMR NMR measurement conditions：pH 6.5；300 K；Ionic strength (raw mmCIF value) 400 mM KCl；Pressure ambient NMR sample composition：1 mM Calmodulin U-15N, 20 mM MES, 400 mM KCl, 90% H20, 10% D20 | 90%H20, 10% D20 NMR sample composition：1 mM Calmodulin U-15N-13C, 20 mM MES, 400 mM KCl, 90% H20, 10% D20 | 90%H20, 10% D20 | Resolution not provided |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 1SW8 | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1CDL TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX Deposited 1993-10-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–147（147 aa）
|
Not recorded | CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1CDL TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX Deposited 1993-10-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–147（147 aa）
|
Not recorded | CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1CDL TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX Deposited 1993-10-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain C
1–147（147 aa）
|
Not recorded | CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1CDL TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX Deposited 1993-10-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–147（147 aa）
|
Not recorded | CA CALCIUM ION × 4 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.00 Å |
| 1CLL CALMODULIN STRUCTURE REFINED AT 1.7 ANGSTROMS RESOLUTION Deposited 1992-09-29 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 EOH ETHANOL × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.70 Å |
| 1CTR DRUG BINDING BY CALMODULIN: CRYSTAL STRUCTURE OF A CALMODULIN-TRIFLUOPERAZINE COMPLEX Deposited 1994-09-21 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 TFP 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 2.45 Å |
| 1IWQ Crystal Structure of MARCKS calmodulin binding domain peptide complexed with Ca2+/Calmodulin Deposited 2002-05-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；295 K；PEG 6000, sodium acetate, calcium chrolide, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.00 Å R-free 0.267 |
| 1IWQ Crystal Structure of MARCKS calmodulin binding domain peptide complexed with Ca2+/Calmodulin Deposited 2002-05-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；295 K；PEG 6000, sodium acetate, calcium chrolide, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.00 Å R-free 0.267 |
| 1J7O Solution structure of Calcium-calmodulin N-terminal domain Deposited 2001-05-17 | Different construct Different mutation/modification Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–76（76 aa）
Fragment：N-TERMINAL DOMAIN
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 100mM KCl；Pressure ambient
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 10mM KCl；Pressure ambient
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 100mM KCl；Pressure ambient
NMR sample composition
1mM calmodulin U-15N,13C;
100mM KCl, 16mM CaCl2, pH 7.0 | 95% H2O/5% D2O
NMR sample composition
1mM calmodulin U-15N,13C;
10mM KCl, 16mM CaCl2, pH 7.0;
15 mg/ml Pf1 | 95% H2O/5% D2O
NMR sample composition
0.5mM calmodulin U-15N,13C;
100mM KCl, 6mM CaCl2, pH 7.0;
18 mg/ml Pf1 | 95% H2O/5% D2O
|
Resolution not provided |
| 1J7P Solution structure of Calcium calmodulin C-terminal domain Deposited 2001-05-17 | Different construct Different mutation/modification Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
82–148（67 aa）
Fragment：C-terminal domain
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 100mM KCl；Pressure ambient
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 10mM KCl；Pressure ambient
NMR measurement conditions
pH 7；305 K；Ionic strength (raw mmCIF value) 100mM KCl；Pressure ambient
NMR sample composition
1mM calmodulin U-15N,13C;
100mM KCl, 16mM CaCl2, pH 7.0; | 95% H2O/5% D2O
NMR sample composition
1mM calmodulin U-15N,13C;
10mM KCl, 16mM CaCl2, pH 7.0;
15 mg/ml Pf1; | 95% H2O/5% D2O
NMR sample composition
0.5mM calmodulin U-15N,13C;
100mM KCl, 6mM CaCl2, pH 7.0;
18 mg/ml Pf1; | 95% H2O/5% D2O
|
Resolution not provided |
| 1L7Z Crystal structure of Ca2+/Calmodulin complexed with myristoylated CAP-23/NAP-22 peptide Deposited 2002-03-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 MYR MYRISTIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；277 K；PEG 1000, cacodylate, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.30 Å R-free 0.264 |
| 1PK0 Crystal Structure of the EF3-CaM complexed with PMEApp Deposited 2003-06-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric |
Chain D
1–147（147 aa）
Chain E
1–147（147 aa）
Chain F
1–147（147 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 3 EMA (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE × 3 CA CALCIUM ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；273 K；PEG 8000,ammonium sulfate, glycerol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 273K
|
Resolution 3.30 Å R-free 0.302 |
| 1PK0 Crystal Structure of the EF3-CaM complexed with PMEApp Deposited 2003-06-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain F
1–147（147 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 EMA (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；273 K；PEG 8000,ammonium sulfate, glycerol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 273K
|
Resolution 3.30 Å R-free 0.302 |
| 1PK0 Crystal Structure of the EF3-CaM complexed with PMEApp Deposited 2003-06-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–147（147 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 EMA (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；273 K；PEG 8000,ammonium sulfate, glycerol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 273K
|
Resolution 3.30 Å R-free 0.302 |
| 1PK0 Crystal Structure of the EF3-CaM complexed with PMEApp Deposited 2003-06-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain E
1–147（147 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 EMA (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；273 K；PEG 8000,ammonium sulfate, glycerol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 273K
|
Resolution 3.30 Å R-free 0.302 |
| 1S26 Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site Deposited 2004-01-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–148（148 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 APC DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；PEG 8000, Ammonium Sulfate, Glycerol, cacodylate, pH 6.5, temperature 277K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 3.00 Å R-free 0.304 |
| 1S26 Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site Deposited 2004-01-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain E
1–148（148 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 APC DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；PEG 8000, Ammonium Sulfate, Glycerol, cacodylate, pH 6.5, temperature 277K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 3.00 Å R-free 0.304 |
| 1S26 Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site Deposited 2004-01-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain F
1–148（148 aa）
|
Not recorded | YB YTTERBIUM (III) ION × 1 APC DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；PEG 8000, Ammonium Sulfate, Glycerol, cacodylate, pH 6.5, temperature 277K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 3.00 Å R-free 0.304 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFU Crystal structure of anthrax edema factor (EF) truncation mutant, EF-delta 64 in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.300 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFV Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 3AT 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.35 Å R-free 0.282 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 7 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain O
1–149（149 aa）
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 2 CA CALCIUM ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 8 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain P
1–149（149 aa）
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 2 CA CALCIUM ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFW Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP) Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 9 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain S
1–149（149 aa）
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 CMP ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE × 2 CA CALCIUM ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.40 Å R-free 0.283 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFX Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.20 Å R-free 0.278 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFY Crystal structure of anthrax edema factor (EF) in complex with calmodulin Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.30 Å R-free 0.289 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain O
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain P
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain Q
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain S
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1XFZ Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 1 millimolar exogenously added calcium chloride Deposited 2004-09-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain T
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 CA CALCIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.5；278 K；PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K
|
Resolution 3.25 Å R-free 0.270 |
| 1Y6W Trapped intermediate of calmodulin Deposited 2004-12-07 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–148（148 aa）
|
Mutation：Q41C, D64N, K75C Non-standard monomer：Yes (specific site not provided by mmCIF) | CA CALCIUM ION × 4 MPD (4S)-2-METHYL-2,4-PENTANEDIOL × 1 TBU TERTIARY-BUTYL ALCOHOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.2；277 K；32% (w/v) 2-methyl-2,4-pentanediol, 10% (v/v) t-butanol, 20 mM Na-cacodylate, 5 mM CaCl2, pH 5.2, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.40 Å R-free 0.238 |
| 1YR5 1.7-A structure of calmodulin bound to a peptide from DAP kinase Deposited 2005-02-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
Fragment：residues 1-148
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；295 K；PEG 8000, sodium acetate, calcium chloride, pH 4.8, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 1.70 Å R-free 0.257 |
| 1YRT Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin Deposited 2005-02-04 | Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
75–148（74 aa）
|
Not recorded | CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 5.6；298 K；PEG4000, Isopropanol, Sodium Citrate , pH 5.6, VAPOR DIFFUSION, temperature 298K
|
Resolution 2.10 Å R-free 0.270 |
| 1YRU Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin and 1mM calcium chloride Deposited 2005-02-04 | Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
75–148（74 aa）
|
Not recorded | CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.2；298 K；PEG2000, Tris, pH 6.2, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.50 Å R-free 0.308 |
| 1ZOT crystal structure analysis of the CyaA/C-Cam with PMEAPP Deposited 2005-05-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
83–151（69 aa）
Fragment：C terminal calmodulin
|
Not recorded | MG MAGNESIUM ION × 3 EMA (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；PEG4000, Na Citrate, Propanol, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 277KK
|
Resolution 2.20 Å R-free 0.291 |
| 1ZUZ Calmodulin in complex with a mutant peptide from human DRP-1 kinase Deposited 2005-06-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；295 K；PEG3350, MPD, pH 4.8, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 1.91 Å R-free 0.248 |
| 1ZUZ Calmodulin in complex with a mutant peptide from human DRP-1 kinase Deposited 2005-06-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.8；295 K；PEG3350, MPD, pH 4.8, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 1.91 Å R-free 0.248 |
| 2F3Y Calmodulin/IQ domain complex Deposited 2005-11-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 MG MAGNESIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.3；298 K；32% PEG 4000, 50mM TRIS, 50 mM MgCl2, pH 8.3, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.45 Å R-free 0.219 |
| 2F3Z Calmodulin/IQ-AA domain complex Deposited 2005-11-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.3；298 K；32% PEG 4000, 50mM TRIS, 50 mM MgCl2, pH 8.3, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.60 Å R-free 0.272 |
| 2HF5 The structure and function of a novel two-site calcium-binding fragment of calmodulin Deposited 2006-06-23 | Different construct Different mutation/modification Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
46–113（68 aa）
Fragment：EF-hands 2 and 3 (residues 46-113)
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 7.4；298 K；Ionic strength (raw mmCIF value) 50 mM；Pressure ambient
NMR sample composition
0.5mM CaM2/3 U-15N,13C; 20 mM Tris d11, 50 mM KCl, 10 mM CaCl2, 90% H2O, and 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2JZI Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin Deposited 2008-01-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 6.5；310 K
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] Calmodulin, 1 mM [U-99% 13C; U-99% 15N] Calmodulin binding domain of Calcineurin, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2K0E A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction Deposited 2008-02-02 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR sample composition
0.5 mM Calmodulin
|
Resolution not provided |
| 2K0F Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase Deposited 2008-02-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
6–153（148 aa）
|
Not recorded | CA CALCIUM ION × 4 | SOLUTION NMR mmCIF provides none of the parsed conditions | Resolution not provided |
| 2K0J Solution structure of CaM complexed to DRP1p Deposited 2008-02-04 | Different construct Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
3–149（147 aa）
|
Mutation：N60D | CA CALCIUM ION × 3 LA LANTHANUM (III) ION × 1 |
SOLUTION NMR
NMR measurement conditions
pH 7.5；298 K；Ionic strength (raw mmCIF value) 0.15；Pressure ambient
NMR sample composition
0.4 mM [U-100% 13C; U-100% 15N] calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.4 mM [U-100% 15N] calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2K61 Solution structure of CaM complexed to DAPk peptide Deposited 2008-07-02 | Different construct Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–149（148 aa）
|
Mutation：N60D | CA CALCIUM ION × 3 TB TERBIUM(III) ION × 1 |
SOLUTION NMR
NMR measurement conditions
pH 7.5；298 K；Ionic strength (raw mmCIF value) 0.15；Pressure ambient
NMR sample composition
0.4 mM [U-100% 13C; U-100% 15N] calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.4 mM [U-100% 15N] calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2KNE Calmodulin wraps around its binding domain in the plasma membrane CA2+ pump anchored by a novel 18-1 motif Deposited 2009-08-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 7.5；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR measurement conditions
pH 7.5；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR sample composition
1-2 mM [U-99% 13C; U-99% 15N] entity_1-1, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
1-2 mM [U-99% 13C; U-99% 15N] entity_1-2, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2KUH Halothane binds to druggable sites in calcium-calmodulin: Solution structure of halothane-CaM C-terminal domain Deposited 2010-02-17 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
83–149（67 aa）
Fragment：C-TERMINAL DOMAIN EF-hands 3 and 4
|
Not recorded | CA CALCIUM ION × 2 HLT 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE × 1 |
SOLUTION NMR
NMR measurement conditions
pH 7.2；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR sample composition
2 mM [U-99% 13C; U-99% 15N] CALCIUM ION, 20 mM CALCIUM ION, 20 mM N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
2 mM [U-99% 15N] CALCIUM ION, 20 mM CALCIUM ION, 20 mM N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2L53 Solution NMR Structure of apo-calmodulin in complex with the IQ motif of Human Cardiac Sodium Channel NaV1.5 Deposited 2010-10-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
Fragment：calmodulin
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6.3；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] calmodulin, 1 mM [U-99% 13C; U-99% 15N] entity_2-2, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
1 mM entity_1-3, 1 mM entity_2-4, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2LGF Solution structure of Ca2+/calmodulin complexed with a peptide representing the calmodulin-binding domain of L-selectin Deposited 2011-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
3–149（147 aa）
Fragment：sequence database residues 4-149
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 6.8；303 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR measurement conditions
pH 6.8；303 K；Ionic strength (raw mmCIF value) 0.3；Pressure ambient
NMR sample composition
0.5-0.8 mM [U-13C; U-15N] protein_1, 0.5-0.8 mM protein_2, 4 mM CALCIUM ION, 0.5 mM DSS, 100 mM potassium chloride, 0.03 % sodium azide, 20 mM Bis-Tris, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5-0.8 mM [U-2H; U-15N] protein_1, 0.5-0.8 mM protein_2, 4 mM CALCIUM ION, 0.5 mM DSS, 100 mM potassium chloride, 0.03 % sodium azide, 20 mM Bis-Tris, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5-0.8 mM [1H/13C-methyl Met; U-2H; U-15N] protein_1, 0.5-0.8 mM protein_2, 4 mM CALCIUM ION, 0.5 mM DSS, 100 mM potassium chloride, 0.03 % sodium azide, 20 mM Bis-Tris, 100% D2O | 100% D2O
NMR sample composition
0.5-0.8 mM [U-13C; U-15N] protein_1, 0.5-0.8 mM protein_2, 4 mM CALCIUM ION, 0.5 mM DSS, 300 mM potassium chloride, 0.03 % sodium azide, 20 mM Bis-Tris, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.5-0.8 mM [U-13C; U-15N] protein_1, 0.5-0.8 mM protein_2, 4 mM CALCIUM ION, 0.5 mM DSS, 300 mM potassium chloride, 0.03 % sodium azide, 20 mM Bis-Tris, 16 w/v Pf1 phage, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2LL6 Solution NMR structure of CaM bound to iNOS CaM binding domain peptide Deposited 2011-10-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6；298 K；Pressure ambient
NMR sample composition
1.0 mM [U-99% 13C; U-99% 15N] protein_1, 1.0 mM protein_2, 100 mM potassium chloride, 10 mM calcium chloride, 0.2 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1.0 mM protein_1, 1.0 mM [U-99% 13C; U-99% 15N] protein_2, 100 mM potassium chloride, 10 mM calcium chloride, 0.2 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2LL7 Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide Deposited 2011-10-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6；298 K；Pressure ambient
NMR sample composition
1.0 mM [U-99% 13C; U-99% 15N] protein_1, 1.0 mM protein_2, 100 mM potassium chloride, 10 mM calcium chloride, 0.2 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2LQC NMR solution structure of a Ca2+-Calmodulin with a binding motif (NSCaTE) peptide from the N-terminal cytoplasmic domain of the L-type Voltage-Cated Calcium Channel alpha1C subunit Deposited 2012-02-29 | Different construct Different mutation/modification Different oligomeric state Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–78（77 aa）
Fragment：EF-hands 1 and 2
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition
1 mM [U-100% 13C; U-100% 15N] calmodulin, 2 mM NSCaTE peptide, 55 M H2O, 5 M [U-99% 2H] D2O, 10 mM DTT, 20 mM TRIS, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1 mM [U-100% 13C; U-100% 15N] NSCaTE peptide, 0.5 mM calmodulin, 55 M H2O, 5 M [U-99% 2H] D2O, 10 mM DTT, 20 mM TRIS, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
1 mM [U-100% 13C; U-100% 15N] calmodulin, 2 mM NSCaTE peptide, 7.5 mg Pf1 phage, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2LQP NMR solution structure of the Ca2+-Calmodulin C-terminal domain in a complex with a peptide (NSCaTE) from the L-type Voltage-Gated Calcium Channel alpha1C subunit Deposited 2012-03-10 | Different construct Different mutation/modification Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
79–149（71 aa）
Fragment：EF-hands 3 and 4
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 7；298 K；Ionic strength (raw mmCIF value) 100；Pressure ambient
NMR sample composition
20 mM TRIS, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2LV6 The complex between Ca-Calmodulin and skeletal muscle myosin light chain kinase from combination of NMR and aqueous and contrast-matched SAXS data Deposited 2012-06-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
Experimental method not declared
NMR measurement conditions
pH 6.5；300 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR measurement conditions
pH 6.5；300 K；Ionic strength (raw mmCIF value) 0.15；Pressure ambient
NMR sample composition
0.3 mM [U-13C; U-15N; U-2H] Calmodulin, 0.3 mM ssMLCK, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.06-0.25 mM [U-13C; U-15N; U-2H] Calmodulin, 0.06-0.25 mM ssMLCK, 65% w/v sucrose/H2O | 65% w/v sucrose/H2O
|
Resolution not provided |
| 2M0J 3D Structure of Calmodulin and Calmodulin binding domain of Olfactory cyclic nucleotide-gated ion channel complex Deposited 2012-10-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 6.7；310 K
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] CaM-OLFp-1, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2M0K 3D Structure of Calmodulin and Calmodulin Binding Domain of Rat Olfactory Cyclic Nucleotide-Gated Ion Channel Deposited 2012-10-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 6.7；310 K
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] CaM-OLFp-1, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2M55 NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin Deposited 2013-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 6.36；310 K；Pressure ambient
NMR sample composition
600 uM [U-99% 13C; U-99% 15N] calmodulin, 600 uM alpha-synuclein, 50 mM MES, 100 mM potassium chloride, 3 mM calcium ion, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
700 uM [U-13C; U-15N]-Met,Val,Phe,Gly,Leu,Ala alpha-synuclein, 700 uM calmodulin, 50 mM MES, 100 mM potassium chloride, 3 mM calcium ion, 0.1% sodium azide, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
150 uM [U-99% 13C; U-99% 15N] calmodulin, 150 uM alpha-synuclein, 50 mM MES, 100 mM potassium chloride, 3 mM calcium ion, 10 mg/mL Pf1 phage, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2MG5 Solution Structure of Calmodulin bound to the target peptide of Endothelial Nitrogen Oxide Synthase phosphorylated at Thr495 Deposited 2013-10-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6；298 K；Ionic strength (raw mmCIF value) 150；Pressure ambient
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] protein, 1 mM peptide, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2N27 Competitive inhibition of TRPV1 calmodulin interaction by vanilloids Deposited 2015-04-29 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | CA CALCIUM ION × 4 4DY (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide × 1 |
SOLUTION NMR
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 30；Pressure ambient
NMR sample composition
60 uM [U-98% 13C; U-98% 15N] Calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
60 uM [U-98% 13C; U-98% 15N] Calmodulin, 300 uM capsaicin, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
60 uM [U-98% 13C; U-98% 15N] Calmodulin, 180 uM resiniferatoxin, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2N6A NMR structure of a human calmodulin/connexin-36 peptide hybrid Deposited 2015-08-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
6–147（142 aa）
|
Not recorded | CA CALCIUM ION × 4 |
SOLUTION NMR
NMR measurement conditions
pH 7.4；293 K；Ionic strength (raw mmCIF value) 0.25；Pressure ambient
NMR sample composition
2.0 mM [U-99% 13C; U-99% 15N] protein, 0.0005 w/v sodium azide, 25 mM sodium chloride, 5 mM Tris, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2N77 NMR solution structure of a complex of PEP-19 bound to the C-domain of apo calmodulin Deposited 2015-09-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
77–149（73 aa）
Fragment：EF-hand domains 3 and 4, residues 77-149
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6.3；298 K；Ionic strength (raw mmCIF value) 0.1；Pressure ambient
NMR sample composition
0.8 mM [U-100% 13C; U-100% 15N] C-CaM, 1.0 mM PEP_19, 100 mM potassium chloride, 5 mM [U-2H] EDTA, 10 uM [U-2H] DSS, 10 mM [U-2H] imidazole, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.8 mM [U-100% 13C; U-100% 15N] PEP_19, 1.0 mM C-CaM, 100 mM potassium chloride, 5 mM [U-2H] EDTA, 10 uM [U-2H] DSS, 10 mM [U-2H] imidazole, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
0.8 mM [U-100% 13C; U-100% 15N] C-CaM, 1.0 mM PEP_19, 100 mM potassium chloride, 5 mM [U-2H] EDTA, 10 uM [U-2H] DSS, 10 mM [U-2H] imidazole, 100% D2O | 100% D2O
NMR sample composition
0.8 mM [U-100% 13C; U-100% 15N] PEP, 1.0 mM C-CaM, 100 mM potassium chloride, 5 mM [U-2H] EDTA, 10 uM [U-2H] DSS, 10 mM [U-2H] imidazole, 100% D2O | 100% D2O
NMR sample composition
0.5 mM [U-99% 15N] C-CaM, 1.0 mM PEP_19, 5.0 mM [U-2H] EDTA, 5% C12E5 PEG, 100 mM potassium chloride, 10 mM [U-2H] imidazole, 95% H2O/5% D2O | 95% H2O/5% D2O
|
Resolution not provided |
| 2N8J Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide Synthase Calmodulin Binding Domain Peptide at Physiological Calcium Concentration Deposited 2015-10-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 7.2；298 K；Ionic strength (raw mmCIF value) 0.150；Pressure ambient
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] CaM, 1 mM eNOS, 100 mM potassium chloride, 30 mM MOPS, 4 mM EGTA, 6 mM CaEGTA, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2R28 The complex Structure of Calmodulin Bound to a Calcineurin Peptide Deposited 2007-08-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain A
1–149（149 aa）
Fragment：Calmodulin-binding domain
Chain B
1–149（149 aa）
Fragment：Calmodulin-binding domain
|
Not recorded | CA CALCIUM ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；20% PEG 3350, 0.2M ammonium phosphate, 0.1M citrite acid , pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 1.86 Å R-free 0.280 |
| 2V01 Recombinant vertebrate calmodulin complexed with Pb Deposited 2007-05-04 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–148（148 aa）
|
Not recorded | PB LEAD (II) ION × 8 CA CALCIUM ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；40-50%MPD, PH4
|
Resolution 2.15 Å R-free 0.253 |
| 2V02 Recombinant vertebrate calmodulin complexed with Ba Deposited 2007-05-04 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–148（148 aa）
|
Not recorded | CA CALCIUM ION × 3 BA BARIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；40-50% MPD, PH4
|
Resolution 2.20 Å R-free 0.294 |
| 2VAY Calmodulin complexed with CaV1.1 IQ peptide Deposited 2007-09-05 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
3–148（146 aa）
Fragment：RESIDUES 3-148
|
Not recorded | CA CALCIUM ION × 4 CL CHLORIDE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 8.3；HANGING DROP VAPOR DIFFUSION 1.5 UL 10 MG/ML COMPLEX IN 20 MM MOPS PH7.4, 150 MM NACL, 4 MM CACL2 MIX WITH 4.5 UL WELL SOLUTION, 32% PEG 3350, 50 MM TRIS PH 8.3, 50 MM MGCL2, 5 DAYS AT 20-22 DEGREES C
|
Resolution 1.94 Å R-free 0.272 |
| 2W73 High-resolution structure of the complex between calmodulin and a peptide from calcineurin A Deposited 2008-12-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain A
0–148（149 aa）
Chain B
0–148（149 aa）
|
Not recorded | CA CALCIUM ION × 11 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.45 Å R-free 0.217 |
| 2W73 High-resolution structure of the complex between calmodulin and a peptide from calcineurin A Deposited 2008-12-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain E
0–148（149 aa）
Chain F
0–148（149 aa）
|
Not recorded | CA CALCIUM ION × 9 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.45 Å R-free 0.217 |
| 2WEL Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin Deposited 2009-03-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–149（149 aa）
|
Not recorded | K88 (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE × 1 EDO 1,2-ETHANEDIOL × 6 PO4 PHOSPHATE ION × 2 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7.5；0.1M SODIUM POTASSIUM PHOSPHATE, 20% PEG3350 10% ETHYLENE GLYCOL, pH 7.5
|
Resolution 1.90 Å R-free 0.199 |
| 2X0G X-RAY STRUCTURE OF A DAP-KINASE CALMODULIN COMPLEX Deposited 2009-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
2–149（148 aa）
|
Not recorded | SO4 SULFATE ION × 2 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7.2；0.17M AMMONIUM SULFATE, 25% (W/V) PEG 4000, 15% GLYCEROL, pH 7.2
|
Resolution 2.20 Å R-free 0.267 |
| 2Y4V CRYSTAL STRUCTURE OF HUMAN CALMODULIN IN COMPLEX WITH A DAP KINASE-1 MUTANT (W305Y) PEPTIDE Deposited 2011-01-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7.5；0.1 M HEPES PH 7.5, 25(W/V) PEG 3000
|
Resolution 1.80 Å R-free 0.238 |
| 3BYA Structure of a Calmodulin Complex Deposited 2008-01-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；17-19% PEG 3350, 0.120mM Ammonium Phosphate, 15% Ethylene Glycol, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 1.85 Å R-free 0.232 |
| 3DVE Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex Deposited 2008-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 NI NICKEL (II) ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；292 K；0.1 M Bis-Tris, 25-30 % PEG 2000 MME, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.35 Å R-free 0.271 |
| 3DVJ Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex Deposited 2008-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；292 K；0.1 M Bis-Tris, 25-30 % PEG 2000 MME, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.80 Å R-free 0.298 |
| 3DVK Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex Deposited 2008-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；292 K；0.1 M Bis-Tris, 25-30 % PEG 2000 MME, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.30 Å R-free 0.291 |
| 3DVM Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex Deposited 2008-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；292 K；0.1 M Bis-Tris, 25 % PEG 3350, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.60 Å R-free 0.320 |
| 3EWT Crystal Structure of calmodulin complexed with a peptide Deposited 2008-10-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 5.5；293 K；25%(w/v) PEG8000, 0.2M Sodium Acetate, 0.1M Sodium cacodylate, pH 5.5, EVAPORATION, temperature 293K
|
Resolution 2.40 Å R-free 0.259 |
| 3EWV Crystal Structure of calmodulin complexed with a peptide Deposited 2008-10-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.7；293 K；27%(w/v) PEG8000, 0.1M Magnesium acetate, 0.1M Ammonium acetate, 0.05M Sodium cacodylate, pH 4.7, EVAPORATION, temperature 293K
|
Resolution 2.60 Å R-free 0.282 |
| 3G43 Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer Deposited 2009-02-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric |
Chain A
2–149（148 aa）
Chain B
2–149（148 aa）
Chain C
2–149（148 aa）
Chain D
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 14 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；20% PEG 6000, 1.0 M LiCl, 3% w/v MPD, 100 mM MES, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.10 Å R-free 0.269 |
| 3HR4 Human iNOS Reductase and Calmodulin Complex Deposited 2009-06-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | FMN FLAVIN MONONUCLEOTIDE × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；292 K；PEG 8K, SODIUM ACETATE, SODIUM CHLORATE, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.50 Å R-free 0.309 |
| 3HR4 Human iNOS Reductase and Calmodulin Complex Deposited 2009-06-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–149（149 aa）
|
Not recorded | FMN FLAVIN MONONUCLEOTIDE × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；292 K；PEG 8K, SODIUM ACETATE, SODIUM CHLORATE, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.50 Å R-free 0.309 |
| 3HR4 Human iNOS Reductase and Calmodulin Complex Deposited 2009-06-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain F
1–149（149 aa）
|
Not recorded | FMN FLAVIN MONONUCLEOTIDE × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；292 K；PEG 8K, SODIUM ACETATE, SODIUM CHLORATE, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.50 Å R-free 0.309 |
| 3HR4 Human iNOS Reductase and Calmodulin Complex Deposited 2009-06-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain H
1–149（149 aa）
|
Not recorded | FMN FLAVIN MONONUCLEOTIDE × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5；292 K；PEG 8K, SODIUM ACETATE, SODIUM CHLORATE, pH 5.0, VAPOR DIFFUSION, HANGING DROP, temperature 292K
|
Resolution 2.50 Å R-free 0.309 |
| 3J41 Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy Deposited 2013-05-31 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric |
Chain E
1–149（149 aa）
Chain F
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 8 |
ELECTRON MICROSCOPY
cryo-EM buffer
25mM HEPES, pH 7.4, 5mM CaCl2, 0.3% decylmaltoside；pH 7.4；25mM HEPES, pH 7.4, 5mM CaCl2, 0.3% decylmaltoside
|
Resolution 25.00 Å |
| 3OXQ Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex Deposited 2010-09-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
1–149（149 aa）
Chain D
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 7 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；0.2 M Li2SO4,
24.5% PEG3350,
0.1 M Bis-Tris pH5.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.55 Å R-free 0.288 |
| 3OXQ Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex Deposited 2010-09-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain B
1–149（149 aa）
Chain C
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 7 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.5；293 K；0.2 M Li2SO4,
24.5% PEG3350,
0.1 M Bis-Tris pH5.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 2.55 Å R-free 0.288 |
| 3SUI Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide Deposited 2011-07-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；0.1M MES PH6.0, 2.2-2.8M AMMONIUM SULFATE, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298K
|
Resolution 1.95 Å R-free 0.248 |
| 3UCT Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+ Deposited 2011-10-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
Chain B
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
|
Not recorded | MN MANGANESE (II) ION × 6 ZN ZINC ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；100MM TRIS-CACODYLATE, 25MM ZNCL2, 16% PEG8000, 100MM MNCL2, 20% ETHYLENE GLYCOL, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.234 |
| 3UCT Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+ Deposited 2011-10-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
Chain B
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
|
Not recorded | MN MANGANESE (II) ION × 6 ZN ZINC ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；100MM TRIS-CACODYLATE, 25MM ZNCL2, 16% PEG8000, 100MM MNCL2, 20% ETHYLENE GLYCOL, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.234 |
| 3UCW Structure of MG2+ bound N-Terminal domain of Calmodulin Deposited 2011-10-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
Chain B
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
|
Not recorded | MG MAGNESIUM ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；20MM TRIS CACODYLATE, 32% PEG8000, 25MM MGAC, 1MM EGTA, 50MM KCL, 25% ETHYLENE GLYCOL, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.76 Å R-free 0.233 |
| 3UCW Structure of MG2+ bound N-Terminal domain of Calmodulin Deposited 2011-10-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
Chain D
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
|
Not recorded | MG MAGNESIUM ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；20MM TRIS CACODYLATE, 32% PEG8000, 25MM MGAC, 1MM EGTA, 50MM KCL, 25% ETHYLENE GLYCOL, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.76 Å R-free 0.233 |
| 3UCY Structure of Mg2+ bound N-terminal domain of calmodulin in the presence of Zn2+ Deposited 2011-10-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–80（79 aa）
Fragment：N-terminal domain residues 2-80
|
Not recorded | NA SODIUM ION × 2 MG MAGNESIUM ION × 2 ZN ZINC ION × 4 CAC CACODYLATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；298 K；100MM TRIS CACODYLATE, 25MM ZNCL2, 16% PEG8000, 100MM MGCL2, 20% ETHYLENE GLYCOL, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.80 Å R-free 0.228 |
| 4BW7 Calmodulin in complex with strontium Deposited 2013-06-30 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–149（149 aa）
|
Not recorded | SR STRONTIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；pH 4
|
Resolution 1.81 Å R-free 0.251 |
| 4BW7 Calmodulin in complex with strontium Deposited 2013-06-30 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
1–149（149 aa）
|
Not recorded | SR STRONTIUM ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；pH 4
|
Resolution 1.81 Å R-free 0.251 |
| 4BW7 Calmodulin in complex with strontium Deposited 2013-06-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
Chain C
1–149（149 aa）
|
Not recorded | SR STRONTIUM ION × 9 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；pH 4
|
Resolution 1.81 Å R-free 0.251 |
| 4BW8 Calmodulin with small bend in central helix Deposited 2013-06-30 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；pH 4
|
Resolution 1.80 Å R-free 0.279 |
| 4BW8 Calmodulin with small bend in central helix Deposited 2013-06-30 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；pH 4
|
Resolution 1.80 Å R-free 0.279 |
| 4BYF Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state Deposited 2013-07-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 2 AOV ADP ORTHOVANADATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
18% PEG3350, 0.2 M SODIUM MALONATE PH 7.0
|
Resolution 2.74 Å R-free 0.237 |
| 4BYF Crystal structure of human Myosin 1c in complex with calmodulin in the pre-power stroke state Deposited 2013-07-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 AOV ADP ORTHOVANADATE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
18% PEG3350, 0.2 M SODIUM MALONATE PH 7.0
|
Resolution 2.74 Å R-free 0.237 |
| 4DCK Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM Deposited 2012-01-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain B
1–149（149 aa）
Fragment：Calmodulin
|
Not recorded | MG MAGNESIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6；289 K；20% PEG400, 150mM Magnesium Acetate, 50mM Sodium Cacodylate
, pH 6.0, VAPOR DIFFUSION, SITTING DROP, temperature 289K
|
Resolution 2.20 Å R-free 0.227 |
| 4DCK Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM Deposited 2012-01-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 9 PDB declaration: nonameric |
Chain B
1–149（149 aa）
Fragment：Calmodulin
|
Not recorded | MG MAGNESIUM ION × 9 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 6；289 K；20% PEG400, 150mM Magnesium Acetate, 50mM Sodium Cacodylate
, pH 6.0, VAPOR DIFFUSION, SITTING DROP, temperature 289K
|
Resolution 2.20 Å R-free 0.227 |
| 4DJC 1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex Deposited 2012-02-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 IPA ISOPROPYL ALCOHOL × 9 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；0.1M MES, 60% Isopropanol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.35 Å R-free 0.176 |
| 4GOW Crystal Structure of Ca2+/CaM:Kv7.4 (KCNQ4) B helix complex Deposited 2012-08-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
4–147（144 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；298 K；1.6M ammonium sulfate, 0.2M sodium citrate (pH 6.0), 0.1M sodium tartrate, 4% isopropanol, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 2.60 Å R-free 0.268 |
| 4JPZ Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin Deposited 2013-03-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain C
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 7.5；290 K；14% pEG3350, 300 mM sodium acetate,50 mM Tris pH 7.5, and 2 mM CaCl2, EVAPORATION, temperature 290K
|
Resolution 3.02 Å R-free 0.246 |
| 4JPZ Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin Deposited 2013-03-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain I
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 7.5；290 K；14% pEG3350, 300 mM sodium acetate,50 mM Tris pH 7.5, and 2 mM CaCl2, EVAPORATION, temperature 290K
|
Resolution 3.02 Å R-free 0.246 |
| 4JQ0 Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin Deposited 2013-03-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain C
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 7.5；290 K；20% PEG3350, 0.18 M MgSO4, 0.1 M sodium iodide, and CaCl2, pH 7.5, EVAPORATION, temperature 290K
|
Resolution 3.84 Å R-free 0.320 |
| 4L79 Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin Deposited 2013-06-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | MG MAGNESIUM ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；10% PEG 3350, 100 mM LiOOCCH3, 100 mM HEPES, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.30 Å R-free 0.249 |
| 4LZX Complex of IQCG and Ca2+-free CaM Deposited 2013-08-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；1.6M ammonium sulfate, 1M lithium sulfate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.50 Å R-free 0.187 |
| 4M1L Complex of IQCG and Ca2+-bound CaM Deposited 2013-08-03 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | CA CALCIUM ION × 4 SO4 SULFATE ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；1.6M ammonium sulfate, 1xM lithium sulfate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 2.10 Å R-free 0.228 |
| 4OVN Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation Deposited 2013-12-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 4 SO4 SULFATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；15% PEG 4K, 0.2 M MgSO4 and 10% glycerol
|
Resolution 2.80 Å R-free 0.282 |
| 4OVN Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation Deposited 2013-12-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 3 SO4 SULFATE ION × 1 PO4 PHOSPHATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；15% PEG 4K, 0.2 M MgSO4 and 10% glycerol
|
Resolution 2.80 Å R-free 0.282 |
| 4OVN Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation Deposited 2013-12-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain C
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 5 SO4 SULFATE ION × 1 PO4 PHOSPHATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；15% PEG 4K, 0.2 M MgSO4 and 10% glycerol
|
Resolution 2.80 Å R-free 0.282 |
| 4OVN Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation Deposited 2013-12-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain D
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；15% PEG 4K, 0.2 M MgSO4 and 10% glycerol
|
Resolution 2.80 Å R-free 0.282 |
| 4OVN Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation Deposited 2013-12-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain E
1–149（149 aa）
|
Non-standard monomer：Yes (specific site not provided by mmCIF) | MG MAGNESIUM ION × 2 SO4 SULFATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；15% PEG 4K, 0.2 M MgSO4 and 10% glycerol
|
Resolution 2.80 Å R-free 0.282 |
| 4Q57 Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex Deposited 2014-04-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
10–74（65 aa）
Fragment：N-terminal domain (UNP residues 10-74)
|
Not recorded | CA CALCIUM ION × 2 MG MAGNESIUM ION × 1 CL CHLORIDE ION × 1 EDO 1,2-ETHANEDIOL × 3 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；277 K；0.1 M Bis-Tris, pH 6.5, 0.2 M magnesium chloride, 13% PEG8000, VAPOR DIFFUSION, HANGING DROP, temperature 277K
|
Resolution 1.80 Å R-free 0.187 |
| 4Q5U Structure of calmodulin bound to its recognition site from calcineurin Deposited 2014-04-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；3:1 10 mg/ml protein to mother liquor (24% PEG1000, 20% glycerol), final volume 200 nL, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K
|
Resolution 1.95 Å R-free 0.248 |
| 4UMO Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin Deposited 2014-05-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain C
1–149（149 aa）
Chain D
1–149（149 aa）
|
Not recorded | K POTASSIUM ION × 4 SCN THIOCYANATE ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
277 K；0.3 M POTASSIUM THIOCYANATE, 0.1 M SODIUM ACETATE TRIHYDRATE PH=5.6, 1 MM EGTA AT 4 DEGREES CELSIUS
|
Resolution 3.00 Å R-free 0.247 |
| 4UPU Crystal structure of IP3 3-K calmodulin binding region in complex with Calmodulin Deposited 2014-06-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 48 PDB declaration: 48-meric |
Chain A
2–149（148 aa）
Fragment：RESIDUES 2-149
|
Not recorded | CA CALCIUM ION × 120 GOL GLYCEROL × 24 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4；29% W/V POLYETHYLENE GLYCOL 4000, 0.2 M (NH4)2SO4, 0.1 M SODIUM ACETATE TRIHYDRATE PH 4.0 AND 10 MM SPERMIDINE
|
Resolution 2.34 Å R-free 0.210 |
| 4V0C Crystal Structure of the Kv7.1 proximal C-terminal Domain in Complex with Calmodulin Deposited 2014-09-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric |
Chain C
1–149（149 aa）
Fragment：RESIDUES 1-149
Chain D
1–149（149 aa）
Fragment：RESIDUES 1-149
|
Not recorded | SCN THIOCYANATE ION × 1 CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
0.3 M POTASSIUM THIOCYANATE, 0.1 M SODIUM ACETATE TRIHYDRATE PH=5.6, 5 MM CACL2
|
Resolution 2.86 Å R-free 0.268 |
| 5COC Fusion protein of human calmodulin and B4 domain of protein A from staphylococcal aureus Deposited 2015-07-20 | Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Insufficient information Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
5–78（74 aa）
Fragment：B4 domain (UNP RESIDUES 213-267),N-terminal (UNP RESIDUES 5-78)
|
Mutation：G240A, K261C, L1005A, T1006A, Q1009C | CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；10% w/v PEG 1000, 10% w/v PEG 8000
|
Resolution 2.67 Å R-free 0.259 |
| 5DBR Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate Deposited 2015-08-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
5–149（145 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；0.2M sodium malonate pH 4.0, 20% w/v PEG 3350
|
Resolution 2.25 Å R-free 0.284 |
| 5DOW Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration Deposited 2015-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | SO4 SULFATE ION × 1 CA CALCIUM ION × 4 CL CHLORIDE ION × 1 NA SODIUM ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulfate, lithium sulfate, Tris/HEPES
|
Resolution 1.70 Å R-free 0.141 |
| 5DOW Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration Deposited 2015-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain C
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 CL CHLORIDE ION × 3 NA SODIUM ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulfate, lithium sulfate, Tris/HEPES
|
Resolution 1.70 Å R-free 0.141 |
| 5DOW Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration Deposited 2015-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain E
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 4 CL CHLORIDE ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulfate, lithium sulfate, Tris/HEPES
|
Resolution 1.70 Å R-free 0.141 |
| 5DOW Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration Deposited 2015-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain G
2–149（148 aa）
|
Not recorded | SO4 SULFATE ION × 1 CA CALCIUM ION × 4 CL CHLORIDE ION × 2 NA SODIUM ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；298 K；ammonium sulfate, lithium sulfate, Tris/HEPES
|
Resolution 1.70 Å R-free 0.141 |
| 5DSU Crystal structure of double mutant of N-domain of human calmodulin Deposited 2015-09-17 | Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
3–78（76 aa）
Fragment：UNP residues 3-78
|
Mutation：Q41L, K75I | CA CALCIUM ION × 2 PGE TRIETHYLENE GLYCOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7.5；290 K；37% PEG 400, 100 mM HEPES, 250 MM CaCl2
|
Resolution 1.93 Å R-free 0.264 |
| 5GGM The NMR structure of calmodulin in CTAB reverse micelles Deposited 2016-06-16 | Different construct Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–149（148 aa）
|
Mutation：N60D | CA CALCIUM ION × 3 TB TERBIUM(III) ION × 1 |
SOLUTION NMR
NMR measurement conditions
pH 6.5；298 K；Ionic strength (raw mmCIF value) 100；Pressure 1
NMR sample composition
0.25 mM [U-13C; U-15N; U-2H] Calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
NMR sample composition
0.25 mM [U-13C; U-15N] Calmodulin, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 5I0I Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state Deposited 2016-02-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain C
3–147（145 aa）
Chain G
84–126（43 aa）
|
Not recorded | MPO 3[N-MORPHOLINO]PROPANE SULFONIC ACID × 1 MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；7.5% PEG 10000, 100mM MOPS pH 7.0, 1mM TCEP and 50mM Magnesium acetate
|
Resolution 3.15 Å R-free 0.218 |
| 5I0I Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state Deposited 2016-02-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain E
3–147（145 aa）
Chain I
84–147（64 aa）
|
Not recorded | MPO 3[N-MORPHOLINO]PROPANE SULFONIC ACID × 1 MG MAGNESIUM ION × 1 VO4 VANADATE ION × 1 ADP ADENOSINE-5'-DIPHOSPHATE × 1 SO4 SULFATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；277 K；7.5% PEG 10000, 100mM MOPS pH 7.0, 1mM TCEP and 50mM Magnesium acetate
|
Resolution 3.15 Å R-free 0.218 |
| 5J03 Crystal Structure of a chimeric Kv7.2 - Kv7.3 proximal C-terminal Domain in Complex with Calmodulin Deposited 2016-03-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 5 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.7；292 K；18% PEG 4K and 100 mM calcium acetate
|
Resolution 2.00 Å R-free 0.228 |
| 5J8H Structure of calmodulin in a complex with a peptide derived from a calmodulin-dependent kinase Deposited 2016-04-07 | Different construct Different mutation/modification Different oligomeric state Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Not recorded | CA CALCIUM ION × 2 |
SOLUTION NMR
NMR measurement conditions
pH 6.8；308.15 K；Ionic strength (raw mmCIF value) 20 mM BisTris 150 mM Potassium Chloride 10 mM Calcium Chloride；Pressure 1
NMR measurement conditions
pH 6.8；308.15 K；Ionic strength (raw mmCIF value) 20 mM BisTris 150 mM Potassium Chloride 10 mM Calcium Chloride；Pressure 1
NMR measurement conditions
pH 6.8；308.15 K；Ionic strength (raw mmCIF value) 20 mM BisTris 150 mM Potassium Chloride 10 mM Calcium Chloride；Pressure 1
NMR measurement conditions
pH 6.8；308.15 K；Ionic strength (raw mmCIF value) 20 mM BisTris 150 mM Potassium Chloride 10 mM Calcium Chloride；Pressure 1
NMR sample composition
320 uM [U-99% 13C; U-99% 15N] Calmodulin, 320 uM eEF2K_74-100, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
595 uM [U-99% 13C; U-99% 15N] eEF2K_74-100, 595 uM Calmodulin, 95% H2O/5% D2O | 95% H2O/5% D2O
NMR sample composition
320 uM [U-99% 13C; U-99% 15N] Calmodulin, 320 uM eEF2K_74-100, 100% D2O | 100% D2O
NMR sample composition
320 uM [U-99% 13C; U-99% 15N] eEF2K_74-100, 320 uM Calmodulin, 100% D2O | 100% D2O
|
Resolution not provided |
| 5JQA CaM:RM20 complex Deposited 2016-05-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1 M sodium acetate, pH 4.6, 25% w/v PEG4000
|
Resolution 1.80 Å R-free 0.188 |
| 5JTH Crystal structure of E67A calmodulin - CaM:RM20 analog complex Deposited 2016-05-09 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1M Sodium Acetate pH 4.6, 25%(w/v) PEG 4000, 20mM CaCl2
|
Resolution 1.84 Å R-free 0.196 |
| 5K7L Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin Deposited 2016-05-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: dodecameric |
Chain B
1–149（149 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 Y01 CHOLESTEROL HEMISUCCINATE × 4 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；Plunged into liquid ethane (FEI VITROBOT MARK IV)
|
Resolution 3.78 Å |
| 5K7L Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin Deposited 2016-05-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: trimeric |
Chain B
1–149（149 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 Y01 CHOLESTEROL HEMISUCCINATE × 1 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；Plunged into liquid ethane (FEI VITROBOT MARK IV)
|
Resolution 3.78 Å |
| 5K7L Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin Deposited 2016-05-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: trimeric |
Chain B
1–149（149 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 Y01 CHOLESTEROL HEMISUCCINATE × 1 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；Plunged into liquid ethane (FEI VITROBOT MARK IV)
|
Resolution 3.78 Å |
| 5K8Q Crystal Structure of Calcium-loaded Calmodulin in complex with STRA6 CaMBP2-site peptide. Deposited 2016-05-30 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 4 IMD IMIDAZOLE × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 5.5；281 K；0.1M Imidazole pH 5.5, 28%(v/v) PEGMME 550
|
Resolution 1.74 Å R-free 0.267 |
| 5NIN Crystal Structure of AKAP79 calmodulin binding domain peptide in complex with Ca2+/Calmodulin Deposited 2017-03-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 2 SO4 SULFATE ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.4；287 K；2.4 M ammonium sulphate, 50 mM citrate pH 5.4, 0.3 M NDSB-195
|
Resolution 1.70 Å R-free 0.194 |
| 5NIN Crystal Structure of AKAP79 calmodulin binding domain peptide in complex with Ca2+/Calmodulin Deposited 2017-03-24 | Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.4；287 K；2.4 M ammonium sulphate, 50 mM citrate pH 5.4, 0.3 M NDSB-195
|
Resolution 1.70 Å R-free 0.194 |
| 5TP5 Solution structure of the calcium deficient mutant calmodulin CaM1234 Deposited 2016-10-19 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–149（148 aa）
|
Not recorded | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6；298 K；Ionic strength (raw mmCIF value) 150；Pressure 1
NMR sample composition
100 mM potassium chloride, 1 mM [U-99% 13C; U-99% 15N] CaM1234, 0.2 mM sodium azide, 0.2 mM EDTA, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 5TP6 Solution structure of the CaM34 with the iNOS CaM binding domain peptide Deposited 2016-10-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
|
Mutation：D93A, D129A | No recorded non-water small molecule |
SOLUTION NMR
NMR measurement conditions
pH 6；298 K；Ionic strength (raw mmCIF value) 100；Pressure 1
NMR sample composition
1 mM [U-99% 13C; U-99% 15N] CaM34, 1 mM iNOS CaM binding domain peptide, 100 mM potassium chloride, 10 mM Calcium chloride, 0.2 mM sodium azide, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 5V03 A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA Deposited 2017-02-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain R
1–149（149 aa）
|
Not recorded | SO4 SULFATE ION × 1 658 N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-amine × 1 CA CALCIUM ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonia sulfate
|
Resolution 1.58 Å R-free 0.220 |
| 5VMS CryoEM structure of Xenopus KCNQ1 channel Deposited 2017-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 12 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE；90-100% humidity
|
Resolution 3.70 Å |
| 5VMS CryoEM structure of Xenopus KCNQ1 channel Deposited 2017-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 3 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE；90-100% humidity
|
Resolution 3.70 Å |
| 5VMS CryoEM structure of Xenopus KCNQ1 channel Deposited 2017-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
1–149（149 aa）
|
Not recorded | CA CALCIUM ION × 3 |
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.2
cryo-EM vitrification conditions
Cryogen ETHANE；90-100% humidity
|
Resolution 3.70 Å |
| 5WSU Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 5.6；289 K；0.1M sodium citrate tribasic (pH 5.6), 20%(v/v) isopropanol, 20%(w/v) PEG 4,000
|
Resolution 3.00 Å R-free 0.290 |
| 5WSU Crystal structure of Myosin VIIa IQ5-SAH in complex with apo-CaM Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain B
2–149（148 aa）
Fragment：UNP residues 2-149
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 5.6；289 K；0.1M sodium citrate tribasic (pH 5.6), 20%(v/v) isopropanol, 20%(w/v) PEG 4,000
|
Resolution 3.00 Å R-free 0.290 |
| 5WSV Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain A
1–147（147 aa）
Fragment：UNP residues 1-147
|
Not recorded | CA CALCIUM ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.5；289 K；0.2M ammonium sulfate, 0.1M Bis-Tris (pH 6.5), 25%(w/v) PEG 3,500
|
Resolution 2.33 Å R-free 0.262 |
| 5WSV Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric |
Chain C
1–147（147 aa）
Fragment：UNP residues 1-147
|
Not recorded | CA CALCIUM ION × 4 SO4 SULFATE ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6.5；289 K；0.2M ammonium sulfate, 0.1M Bis-Tris (pH 6.5), 25%(w/v) PEG 3,500
|
Resolution 2.33 Å R-free 0.262 |
105 other PDB entries and 176 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | CALM_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–79； UniProt 2–80 |
