← Back to search
2w73

High-resolution structure of the complex between calmodulin and a peptide from calcineurin A

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

CALMODULIN

HOMO SAPIENS

UniProt P62158

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT ALPHA ISOFORM × 2 （Q08209） CALCIUM ION × 11 water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT ALPHA ISOFORM × 2 （Q08209） CALCIUM ION × 9 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1cll 1ctr 1j7o 1j7p 1sw8 1y6w 2hf5 2k0e 2k0j 2k61 2kuh 2lqp

22 assemblies; showing the first 12

Homodimer
3uct 3uct 3ucw 3ucw 3ucy 4bw7

6 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1cdl 1cdl 1cdl 1cdl 1iwq 1iwq 1l7z 1pk0 1pk0 1pk0 1pk0 1s26

149 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CALM_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–149； UniProt 0–148 Author chain B； PDBConstruct 1–149； UniProt 0–148 Author chain E； PDBConstruct 1–149； UniProt 0–148 Author chain F； PDBConstruct 1–149； UniProt 0–148

SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT ALPHA ISOFORM

OrganismNot specified

UniProt Q08209

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 4 CALMODULIN × 2 （P62158） CALCIUM ION × 11 water × 4 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 CALMODULIN × 2 （P62158） CALCIUM ION × 9 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
5c1v 5c1v

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1aui 1m63 1mf8 2jog 2jzi 2p6b 2r28 2w73 2w73 3ll8 3ll8 3ll8

24 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PP2BA_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain K； PDBConstruct 1–17； UniProt 395–411 Author chain L； PDBConstruct 1–17； UniProt 395–411 Author chain M； PDBConstruct 1–17； UniProt 395–411 Author chain O； PDBConstruct 1–17； UniProt 395–411

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id2w73
Deposition date deposition_date2008-12-19
Structure title titleHigh-resolution structure of the complex between calmodulin and a peptide from calcineurin A
Keywords keywords;METAL-BINDING PROTEIN, PROTEIN PHOSPHATASE, ALTERNATIVE SPLICING, PHOSPHOPROTEIN, UBL CONJUGATION, CALMODULIN-BINDING, CALCIUM, HYDROLASE, CALMODULIN, ACETYLATION, METHYLATION, POLYMORPHISM, METAL-BINDING, ZINC, IRON, DIMER, EF HAND, NUCLEUS, METAL BINDING PROTEIN ;; METAL BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2w73__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2w73__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2w73__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）23.88 Å
Rg (electron density)22.78 Å
Total Rg23.58 Å
Atom count2560
Residues323
Excluded volume45374 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2w73__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 2w73__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▼

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd2w73a_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.5 — Calmodulin-like
Domain ID domain_idd2w73b_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.5 — Calmodulin-like
Domain ID domain_idd2w73e_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.5 — Calmodulin-like
Domain ID domain_idd2w73f_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.5 — Calmodulin-like
▶

7. Citations (1)