1tje

Crystal structure of the editing domain of threonyl-tRNA synthetase

Method: X-RAY DIFFRACTION

1. Protein Identity and Related Structures Protein Identity & Related Structures

Threonyl-tRNA synthetase

Escherichia coli

UniProt P0A8M3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SYT_ECOLI
Isoform
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–224; UniProt 1–224

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

2. Structure Basics 2. Structure Basics

Entry ID entry_id1tje
Deposition date deposition_date2004-06-04
Structure title titleCrystal structure of the editing domain of threonyl-tRNA synthetase
Keywords keywordsLIGASE; LIGASE
Experimental Method methodX-RAY DIFFRACTION

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1tje__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1tje__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1tje__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)19.58 Å
Rg (electron density)18.57 Å
Total Rg19.41 Å
Atom count1786
Residues224
Excluded volume31509 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1tje__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download

4. Crystallography and Experiment 4. Crystallography & Experiment

5. Entities and Polymers Entities & Polymers (2)

6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1tjea1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.15 — beta-Grasp (ubiquitin-like)
Superfamily Superfamily superfamilyd.15.10 — TGS-like
Family Family familyd.15.10.1 — TGS domain
Domain ID domain_idd1tjea2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.67 — RRF/tRNA synthetase additional domain-like
Superfamily Superfamily superfamilyd.67.1 — ThrRS/AlaRS common domain
Family Family familyd.67.1.1 — Threonyl-tRNA synthetase (ThrRS), second 'additional' domain

CATH v4.4 (3 domains)

Domain ID domain_id1tjeA01
Class class3 — Alpha Beta
Architecture architecture10 — Roll
Topology topology20 — Ubiquitin-like (UB roll)
Homologous superfamily homologous superfamily30 — Beta-grasp domain
Domain ID domain_id1tjeA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology980 — Threonyl-tRNA Synthetase; Chain A, domain 2
Homologous superfamily homologous superfamily10 — Threonyl-trna Synthetase; Chain A, domain 2
Domain ID domain_id1tjeA03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology54 — Replication Terminator Protein; Chain A, domain 2
Homologous superfamily homologous superfamily20

7. Citations (1)