物种未注明
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Tubulin beta chain × 1 （P02554） GUANOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-DIPHOSPHATE × 1 EPOTHILONE A × 1 | 与蛋白数一致 |
| UniProt名称 | TBA_PIG |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–440； UniProt 1–440 |
物种未注明
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Tubulin alpha chain × 1 （P02550） GUANOSINE-5'-TRIPHOSPHATE × 1 GUANOSINE-5'-DIPHOSPHATE × 1 EPOTHILONE A × 1 | 与蛋白数一致 |
| UniProt名称 | TBB_PIG |
| Isoform | — |
| PDB实体 | 2 |
| 链与序列区间 | 作者链 B； PDB构建体 1–427； UniProt 1–427 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 1tvk |
| 沉积日期 deposition_date | 2004-06-29 |
| 结构标题 title | The binding mode of epothilone A on a,b-tubulin by electron crystallography |
| 关键词 keywords | epothilone; taxol; ligand interactions, CELL CYCLE, STRUCTURAL PROTEIN; CELL CYCLE, STRUCTURAL PROTEIN |
| 实验方法 method | ELECTRON CRYSTALLOGRAPHY |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 29.31 Å |
| Rg（电子密度） | 28.68 Å |
| 总 Rg | 29.29 Å |
| 原子数 | 6672 |
| 残基数 | 838 |
| 排除体积 | 117800 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d1tvka1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.32 — Tubulin nucleotide-binding domain-like |
| 超家族 Superfamily superfamily | c.32.1 — Tubulin nucleotide-binding domain-like |
| 家族 Family family | c.32.1.1 — Tubulin, GTPase domain |
| 结构域编号 domain_id | d1tvka2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.79 — Bacillus chorismate mutase-like |
| 超家族 Superfamily superfamily | d.79.2 — Tubulin C-terminal domain-like |
| 家族 Family family | d.79.2.1 — Tubulin, C-terminal domain |
| 结构域编号 domain_id | d1tvkb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.32 — Tubulin nucleotide-binding domain-like |
| 超家族 Superfamily superfamily | c.32.1 — Tubulin nucleotide-binding domain-like |
| 家族 Family family | c.32.1.1 — Tubulin, GTPase domain |
| 结构域编号 domain_id | d1tvkb2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.79 — Bacillus chorismate mutase-like |
| 超家族 Superfamily superfamily | d.79.2 — Tubulin C-terminal domain-like |
| 家族 Family family | d.79.2.1 — Tubulin, C-terminal domain |
| 结构域编号 domain_id | 1tvkA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1440 — Tubulin/FtsZ, GTPase domain |
| 结构域编号 domain_id | 1tvkA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1330 — 60s Ribosomal Protein L30; Chain: A; |
| 同源超家族 H-superfamily homologous superfamily | 20 — Tubulin/FtsZ, C-terminal domain |
| 结构域编号 domain_id | 1tvkA03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 600 — Helix hairpin bin |
| 结构域编号 domain_id | 1tvkB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1440 — Tubulin/FtsZ, GTPase domain |
| 结构域编号 domain_id | 1tvkB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 1330 — 60s Ribosomal Protein L30; Chain: A; |
| 同源超家族 H-superfamily homologous superfamily | 20 — Tubulin/FtsZ, C-terminal domain |
| 结构域编号 domain_id | 1tvkB03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 287 — Helix Hairpins |
| 同源超家族 H-superfamily homologous superfamily | 600 — Helix hairpin bin |