Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | water × 1 | Consistent with protein count |
| UniProt name | RASA1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–334； UniProt 714–1047 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1wer |
| Deposition date deposition_date | 1996-11-20 |
| Structure title title | RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP |
| Keywords keywords | GTPASE ACTIVATION, RAS, GAP, SIGNAL TRANSDUCTION, GROWTH REGULATION, CANCER; GTPASE ACTIVATION |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 24.38 Å |
| Rg (electron density) | 23.42 Å |
| Total Rg | 24.10 Å |
| Atom count | 2589 |
| Residues | 324 |
| Excluded volume | 46592 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1wera_ |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.116 — GTPase activation domain, GAP |
| Superfamily Superfamily superfamily | a.116.1 — GTPase activation domain, GAP |
| Family Family family | a.116.1.2 — p120GAP domain-like |
| Domain ID domain_id | 1werA01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 506 — GTPase Activation - p120GAP; domain 1 |
| Homologous superfamily homologous superfamily | 10 — GTPase Activation - p120gap; domain 1 |
| Domain ID domain_id | 1werA02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 506 — GTPase Activation - p120GAP; domain 1 |
| Homologous superfamily homologous superfamily | 10 — GTPase Activation - p120gap; domain 1 |