← Back to search
1xqs

Crystal structure of the HspBP1 core domain complexed with the fragment of Hsp70 ATPase domain

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

HSPBP1 protein

Homo sapiens

UniProt Q9NZL4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Heat shock 70 kDa protein 1 × 1 （P08107） ADENOSINE MONOPHOSPHATE × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Heat shock 70 kDa protein 1 × 1 （P08107） ADENOSINE MONOPHOSPHATE × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1xqr 1xqr 8x87 8x87 8x87 8x87

6 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1xqs 1xqs

2 assemblies

View Construct and Data Evidence
UniProt name HPBP1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–280； UniProt 84–359 Author chain B； PDBConstruct 5–280； UniProt 84–359

Heat shock 70 kDa protein 1

Homo sapiens

UniProt P08107

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 HSPBP1 protein × 1 （Q9NZL4） ADENOSINE MONOPHOSPHATE × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 HSPBP1 protein × 1 （Q9NZL4） ADENOSINE MONOPHOSPHATE × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1hjo 1s3x 2lmg 3atu 3atv 3ay9 3jxu 4wv5 4wv5 4wv7 4wv7

11 assemblies

Homodimer
3lof 3lof 3lof

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1xqs 1xqs 3a8y 3a8y 3d2e 3d2e 3d2f 3d2f 4j8f 4j8f 4po2 4po2

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HSP71_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 4–191； UniProt 184–371 Author chain D； PDBConstruct 4–191； UniProt 184–371

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1xqs
Deposition date deposition_date2004-10-13
Structure title titleCrystal structure of the HspBP1 core domain complexed with the fragment of Hsp70 ATPase domain
Keywords keywordsarmadillo repeat, superhelical twist, CHAPERONE; CHAPERONE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1xqs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1xqs__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1xqs__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）25.39 Å
Rg (electron density)24.72 Å
Total Rg25.33 Å
Atom count3385
Residues429
Excluded volume60096 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1xqs__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1xqs__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▼

6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1xqsa1
Class classa — All alpha proteins
Fold Fold folda.118 — alpha-alpha superhelix
Superfamily Superfamily superfamilya.118.1 — ARM repeat
Family Family familya.118.1.21 — HspBP1 domain
Domain ID domain_idd1xqsb1
Class classa — All alpha proteins
Fold Fold folda.118 — alpha-alpha superhelix
Superfamily Superfamily superfamilya.118.1 — ARM repeat
Family Family familya.118.1.21 — HspBP1 domain

CATH v4.4 (6 domains)

Domain ID domain_id1xqsA00
Class class1 — Mainly Alpha
Architecture architecture25 — Alpha Horseshoe
Topology topology10 — Leucine-rich Repeat Variant
Homologous superfamily homologous superfamily10 — Leucine-rich Repeat Variant
Domain ID domain_id1xqsB00
Class class1 — Mainly Alpha
Architecture architecture25 — Alpha Horseshoe
Topology topology10 — Leucine-rich Repeat Variant
Homologous superfamily homologous superfamily10 — Leucine-rich Repeat Variant
Domain ID domain_id1xqsC01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology420 — Nucleotidyltransferase; domain 5
Homologous superfamily homologous superfamily40 — ATPase, nucleotide binding domain
Domain ID domain_id1xqsC02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology640 — Actin; Chain A, domain 4
Homologous superfamily homologous superfamily10 — ATPase, substrate binding domain, subdomain 4
Domain ID domain_id1xqsD01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology420 — Nucleotidyltransferase; domain 5
Homologous superfamily homologous superfamily40 — ATPase, nucleotide binding domain
Domain ID domain_id1xqsD02
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology640 — Actin; Chain A, domain 4
Homologous superfamily homologous superfamily10 — ATPase, substrate binding domain, subdomain 4
▶

7. Citations (1)