2awi
Structure of PrgX Y153C mutant
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 2awi |
| 沉积日期 deposition_date | 2005-09-01 |
| 结构标题 title | Structure of PrgX Y153C mutant |
| 关键词 keywords | Repressor, pheromone, DNA binding, regulatory domain, TRANSCRIPTION; TRANSCRIPTION |
| 实验方法 method | X-RAY DIFFRACTION |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 71.55 Å |
| 回转半径 Rg (电子) rg_electron | 72.34 Å |
| 零角强度 I(0) i0 | 2222400000.00 |
| 分子量 molecular_weight | 418280.0 kDa |
| 排除体积 excluded_volume | 531310 ų |
| 包络体积 envelope_volume | 794330 ų |
| 水化壳体积 shell_volume | 101340 ų |
| 包络直径 envelope_diameter | 273.1 Å |
| 壳层 Rg shell_rg | 60.23 Å |
| 包络 Rg envelope_rg | 71.77 Å |
| 形状 Rg shape_rg | 72.31 Å |
| 总 Rg total_rg | 72.21 Å |
| 总原子数 total_atoms | 29387 |
| 残基数 n_residues | 3514 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 228.7 Å |
| Rg (实空间) rg_real | 71.02 Å |
| Rg 误差 (实空间) rg_real_error | 1.68 Å |
| I(0) (实空间) i0_real | 2.2090e+09 |
| I(0) 误差 (实空间) i0_real_error | 5.0810e+07 |
| Rg (倒空间) rg_reciprocal | 69.42 Å |
| I(0) (倒空间) i0_reciprocal | 2211000000.0000 |
| 解质量估计 total_estimate | 0.8448 |
| 解质量评级 solution_quality | GOOD a GOOD solution |
| P(r) 峰数 n_peaks | 2 |
| 主峰位置 r_peak_primary | 72.8 Å |
| 偏度 Skewness skewness | 0.551 |
| 峰度 Kurtosis kurtosis | -0.245 |
| 角度范围 angular_range | — – 0.1100 Å−1 |
| 当前正则化参数 α current_alpha | 0.0745 |
| 最高正则化参数 α highest_alpha | 101400000.0000 |
| 实空间数据点数 n_real_points | 23 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 0.891; Stabil: 0.997; Sysdev: 1.000; Positv: 1.000; Valcen: 0.992; Smooth: 0.297 |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合体信息 (2)
6. 折叠分类 (SCOP + CATH) 48 domains
SCOP 2.08 (24 domains)
| 结构域编号 domain_id | d2awia1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awia2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awib1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awib2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awic1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awic2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awid1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awid2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awie1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awie2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awif1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awif2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awig1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awig2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awih1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awih2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awii1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awii2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awij1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awij2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awik1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awik2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
| 结构域编号 domain_id | d2awil1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.35 — lambda repressor-like DNA-binding domains |
| 超家族 Superfamily superfamily | a.35.1 — lambda repressor-like DNA-binding domains |
| 家族 Family family | a.35.1.11 — PrgX N-terminal domain-like |
| 结构域编号 domain_id | d2awil2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.118 — alpha-alpha superhelix |
| 超家族 Superfamily superfamily | a.118.8 — TPR-like |
| 家族 Family family | a.118.8.4 — PrgX C-terminal domain-like |
CATH v4.4 (24 domains)
| 结构域编号 domain_id | 2awiA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiB01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiB02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiC01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiC02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiD01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiD02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiE01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiE02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiF01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiF02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiG01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiG02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiH01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiH02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiI01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiI02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiJ01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiJ02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiK01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiK02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |
| 结构域编号 domain_id | 2awiL01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 260 — 434 Repressor (Amino-terminal Domain) |
| 同源超家族 H-superfamily homologous superfamily | 40 — lambda repressor-like DNA-binding domains |
| 结构域编号 domain_id | 2awiL02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 25 — Alpha Horseshoe |
| 拓扑 Topology topology | 40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat |
| 同源超家族 H-superfamily homologous superfamily | 400 — |