2c6s

human adenovirus penton base 2 12 chimera

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

ADENOVIRUS 2,12 PENTON BASE CHIMERA

HUMAN ADENOVIRUS C

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 60	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PEN3_ADE02
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–523； UniProt 49–571 Author chain B； PDBConstruct 1–523； UniProt 49–571 Author chain C； PDBConstruct 1–523； UniProt 49–571 Author chain D； PDBConstruct 1–523； UniProt 49–571 Author chain E； PDBConstruct 1–523； UniProt 49–571 Author chain F； PDBConstruct 1–523； UniProt 49–571 Author chain G； PDBConstruct 1–523； UniProt 49–571 Author chain H； PDBConstruct 1–523； UniProt 49–571 Author chain I； PDBConstruct 1–523； UniProt 49–571 Author chain J； PDBConstruct 1–523； UniProt 49–571 Author chain K； PDBConstruct 1–523； UniProt 49–571 Author chain L； PDBConstruct 1–523； UniProt 49–571 Author chain M； PDBConstruct 1–523； UniProt 49–571 Author chain N； PDBConstruct 1–523； UniProt 49–571 Author chain O； PDBConstruct 1–523； UniProt 49–571

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2c6s
Deposition date deposition_date	2005-11-11
Structure title title	human adenovirus penton base 2 12 chimera
Keywords keywords	VIRUS/VIRAL PROTEIN, ADENOVIRUS, CAPSID, PENTON, DODECAHEDRA, FIBER, VIRAL PROTEIN, VIRUS-VIRAL PROTEIN complex; VIRUS/VIRAL PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2c6s__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2c6s__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2c6s__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	97.65 Å
Rg (electron density)	97.24 Å
Total Rg	97.35 Å
Atom count	212040
Residues	26640
Excluded volume	3755000 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2c6s__assembly_1__model_1`	60-meric （60）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

Domain ID domain_id	2c6sA01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sA02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sB01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sB02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sC01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sC02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sD01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sD02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sE01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sE02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sF01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sF02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sG01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sG02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sH01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sH02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sI01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sI02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sJ01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sJ02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sK01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sK02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sL01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sL02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sM01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sM02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sN01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sN02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

Domain ID domain_id	2c6sO01
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	120 — Jelly Rolls
Homologous superfamily homologous superfamily	550 — Penton protein; domain 1

Domain ID domain_id	2c6sO02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1620 — adenovirus 2 penton base, domain 2
Homologous superfamily homologous superfamily	10 — adenovirus 2 penton base, domain 2

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Unit-cell length a length_a	266.500 Å
Unit-cell length b length_b	292.900 Å
Unit-cell length c length_c	307.300 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	120

Space group space_group	I 2 2 2
Space-group number int_tables_number	23
Crystal system crystal_system	—

Resolution resolution	3.600 Å
Low-resolution limit resolution_low	15.000 Å
R factor r_factor	0.2760
R_work r_work	0.2750
R_free r_free	0.3400

Description description	ADENOVIRUS 2,12 PENTON BASE CHIMERA
Molecular weight formula_weight	58202.7 kDa
Source method src_method	man
Copy count entity_count	15

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O
Atom count atom_count	53010

human adenovirus penton base 2 12 chimera

1. Protein Identity and Related Structures Protein Identity & Related Structures

ADENOVIRUS 2,12 PENTON BASE CHIMERA

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2c6s__assembly_1__model_1

2c6s__assembly_1__model_1 | I(q)

2c6s__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

7. Citations (1)

Source organism organism	HUMAN ADENOVIRUS C
NCBI taxonomy ID ncbi_taxonomy_id	10515
Host organism host_organism	TRICHOPLUSIA NI

human adenovirus penton base 2 12 chimera

1. Protein Identity and Related Structures Protein Identity & Related Structures

ADENOVIRUS 2,12 PENTON BASE CHIMERA

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2c6s__assembly_1__model_1

2c6s__assembly_1__model_1 | I(q)

2c6s__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

7. Citations (1)