2ex3

Bacteriophage phi29 DNA polymerase bound to terminal protein

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

DNA polymerase

Bacillus phage phi29

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 3	与蛋白数一致
2	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 3	与蛋白数一致
3	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 3	与蛋白数一致
4	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 3	与蛋白数一致
5	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 2	与蛋白数一致
6	蛋白异源复合物	异源复合物	蛋白 2	DNA terminal protein × 1 （P03681） LEAD (II) ION × 2	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	DPOL_BPPH2
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–575； UniProt 1–575 作者链 C； PDB构建体 1–575； UniProt 1–575 作者链 E； PDB构建体 1–575； UniProt 1–575 作者链 G； PDB构建体 1–575； UniProt 1–575 作者链 I； PDB构建体 1–575； UniProt 1–575 作者链 K； PDB构建体 1–575； UniProt 1–575

DNA terminal protein

Bacillus phage phi29

UniProt P03681

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 3	与蛋白数一致
2	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 3	与蛋白数一致
3	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 3	与蛋白数一致
4	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 3	与蛋白数一致
5	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 2	与蛋白数一致
6	蛋白异源复合物	异源复合物	蛋白 2	DNA polymerase × 1 （P03680） LEAD (II) ION × 2	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	TERM_BPPH2
Isoform	—
PDB实体	2
链与序列区间	作者链 B； PDB构建体 35–230； UniProt 71–266 作者链 D； PDB构建体 35–230； UniProt 71–266 作者链 F； PDB构建体 35–230； UniProt 71–266 作者链 H； PDB构建体 35–230； UniProt 71–266 作者链 J； PDB构建体 35–230； UniProt 71–266 作者链 L； PDB构建体 35–230； UniProt 71–266

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2ex3
沉积日期 deposition_date	2005-11-07
结构标题 title	Bacteriophage phi29 DNA polymerase bound to terminal protein
关键词 keywords	DNA POLYMERASE: PROTEIN PRIMER COMPLEX, transferase-replication COMPLEX; transferase/replication
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2ex3__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2ex3__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

2ex3__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	31.25 Å
Rg（电子密度）	30.41 Å
总 Rg	30.97 Å
原子数	6185
残基数	766
排除体积	110970 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`2ex3__assembly_1__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`2ex3__assembly_2__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
3	1	`2ex3__assembly_3__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
4	1	`2ex3__assembly_4__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
5	1	`2ex3__assembly_5__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
6	1	`2ex3__assembly_6__model_1`	dimeric （2）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

描述 description	DNA polymerase
分子量 formula_weight	66720.9 kDa
EC 编号 ec_number	2.7.7.7
突变 mutation	D12A/D66A
来源方法 src_method	man
拷贝数 entity_count	6

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,C,E,G,I,K
原子数 atom_count	37108

MKHMPRKMYSCAFETTTKVEDCRVWAYGYMNIEDHSEYKIGNSLDEFMAWVLKVQADLYFHNLKFAGAFIINWLERNGFKWSADGLPNTYNTIISRMGQWYMIDICLGYKGKRKIHTVIYDSLKKLPFPVKKIAKDFKLTVLKGDIDYHKERPVGYKITPEEYAYIKNDIQIIAEALLIQFKQGLDRMTAGSDSLKGFKDIITTKKFKKVFPTLSLGLDKEVRYAYRGGFTWLNDRFKEKEIGEGMVFDVNSLYPAQMYSRLLPYGEPIVFEGKYVWDEDYPLHIQHIRCEFELKEGYIPTIQIKRSRFYKGNEYLKSSGGEIADLWLSNVDLELMKEHYDLYNVEYISGLKFKATTGLFKDFIDKWTYIKTTSEGAIKQLAKLMLNSLYGKFASNPDVTGKVPYLKENGALGFRLGEEETKDPVYTPMGVFITAWARYTTITAAQACYDRIIYCDTDSIHLTGTEIPDVIKDIVDPKKLGYWAHESTFKRAKYLRQKTYIQDIYMKEVDGKLVEGSPDDYTDIKFSVKCAGMTDKIKKEVTFENFKVGFSRKMKPKPVQVPGGVVLVDDTFTIK

来源 Source

来源生物 organism	Bacillus phage phi29
NCBI 分类编号 ncbi_taxonomy_id	10756
宿主生物 host_organism	Escherichia coli

实体 2 Entity 2 polymer

描述 description	DNA terminal protein
分子量 formula_weight	25816.4 kDa
来源方法 src_method	man
拷贝数 entity_count	6

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	B,D,F,H,J,L

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKIKAMKDKEYYAGGKPQGTIEQRIAMTSPAHVTGINRPHDFDFSKVRSYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIKSVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF

来源 Source

来源生物 organism	Bacillus phage phi29
NCBI 分类编号 ncbi_taxonomy_id	10756
宿主生物 host_organism	Bacillus subtilis

实体 3 Entity 3 non-polymer

描述 description	LEAD (II) ION
分子量 formula_weight	207.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	16

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6. 折叠分类 (SCOP + CATH) 66 domains

SCOP 2.08 (18 domains)

结构域编号 domain_id	d2ex3a1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3a2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3b1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

结构域编号 domain_id	d2ex3c1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3c2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3d1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

结构域编号 domain_id	d2ex3e1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3e2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3f1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

结构域编号 domain_id	d2ex3g1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3g2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3h1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

结构域编号 domain_id	d2ex3i1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3i2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3j1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

结构域编号 domain_id	d2ex3k1
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.55 — Ribonuclease H-like motif
超家族 Superfamily superfamily	c.55.3 — Ribonuclease H-like
家族 Family family	c.55.3.5 — DnaQ-like 3'-5' exonuclease

结构域编号 domain_id	d2ex3k2
类 Class class	e — Multi-domain proteins (alpha and beta)
折叠类型 Fold fold	e.8 — DNA/RNA polymerases
超家族 Superfamily superfamily	e.8.1 — DNA/RNA polymerases
家族 Family family	e.8.1.1 — DNA polymerase I

结构域编号 domain_id	d2ex3l1
类 Class class	a — All alpha proteins
折叠类型 Fold fold	a.263 — DNA terminal protein
超家族 Superfamily superfamily	a.263.1 — DNA terminal protein
家族 Family family	a.263.1.1 — DNA terminal protein

CATH v4.4 (48 domains)

结构域编号 domain_id	2ex3A01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3A02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3A03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3A04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3A05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3A06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3B01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3B02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

结构域编号 domain_id	2ex3C01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3C02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3C03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3C04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3C05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3C06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3D01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3D02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

结构域编号 domain_id	2ex3E01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3E02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3E03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3E04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3E05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3E06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3F01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3F02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

结构域编号 domain_id	2ex3G01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3G02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3G03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3G04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3G05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3G06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3H01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3H02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

结构域编号 domain_id	2ex3I01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3I02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3I03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3I04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3I05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3I06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3J01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3J02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

结构域编号 domain_id	2ex3K01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	420 — Nucleotidyltransferase; domain 5
同源超家族 H-superfamily homologous superfamily	10 — Ribonuclease H-like superfamily/Ribonuclease H

结构域编号 domain_id	2ex3K02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	90 — Alpha-Beta Complex
拓扑 Topology topology	1600 — Palm domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — B family DNA polymerase, palm domain

结构域编号 domain_id	2ex3K03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1770 — TPR 1 domain of DNA polymerase
同源超家族 H-superfamily homologous superfamily	10 — TPR 1 domain of DNA polymerase

结构域编号 domain_id	2ex3K04
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily	690 — B family DNA polymerase, finger domain

结构域编号 domain_id	2ex3K05
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	20 — DNA polymerase; domain 5

结构域编号 domain_id	2ex3K06
类 Class class	4 — Few Secondary Structures
架构 Architecture architecture	10 — Irregular
拓扑 Topology topology	80 — Rhinovirus 14, subunit 4
同源超家族 H-superfamily homologous superfamily	30 — DNA polymerase; domain 6

结构域编号 domain_id	2ex3L01
类 Class class	6 — Special
架构 Architecture architecture	10 — Helix non-globular
拓扑 Topology topology	250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
同源超家族 H-superfamily homologous superfamily	960 —

结构域编号 domain_id	2ex3L02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
同源超家族 H-superfamily homologous superfamily	230 — DNA terminal protein Gp3, priming domain

▶

晶胞边长 a length_a	304.933 Å
晶胞边长 b length_b	220.281 Å
晶胞边长 c length_c	217.165 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	45.40 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	24

空间群 space_group	C 1 2 1
空间群编号 int_tables_number	5
晶系 crystal_system	—

分辨率 resolution	3.000 Å
最低分辨率 resolution_low	48.850 Å
R 因子 r_factor	0.2030
R_work r_work	0.2000
R_free r_free	0.2290

Bacteriophage phi29 DNA polymerase bound to terminal protein

1. 蛋白身份与相关结构 Protein Identity & Related Structures

DNA polymerase

当前结构中的状态

数据库中的同蛋白其他状态

DNA terminal protein

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2ex3__assembly_1__model_1

2ex3__assembly_1__model_1 | I(q)

2ex3__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer

聚合物 Polymer

来源 Source

实体 3 Entity 3 non-polymer

6. 折叠分类 (SCOP + CATH) 66 domains

SCOP 2.08 (18 domains)

CATH v4.4 (48 domains)

7. 引用文献 (1)

Bacteriophage phi29 DNA polymerase bound to terminal protein

1. 蛋白身份与相关结构 Protein Identity & Related Structures

DNA polymerase

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

DNA terminal protein

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2ex3__assembly_1__model_1

2ex3__assembly_1__model_1 | I(q)

2ex3__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer

聚合物 Polymer

来源 Source

实体 3 Entity 3 non-polymer

6. 折叠分类 (SCOP + CATH) 66 domains

SCOP 2.08 (18 domains)

CATH v4.4 (48 domains)

7. 引用文献 (1)