2jex

Transcription activator structure reveals redox control of a replication initiation reaction

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

REGULATORY PROTEIN E2

BOVINE PAPILLOMAVIRUS TYPE 1

UniProt P03122

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VE2_BPV1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–209; UniProt 1–209

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2jex
Deposition date deposition_date2007-01-24
Structure title titleTranscription activator structure reveals redox control of a replication initiation reaction
Keywords keywords;NUCLEAR PROTEIN, DNA REPLICATION, PHOSPHORYLATION, TRANSCRIPTION REGULATION, VIRAL TRANSCRIPTION FACTOR, BOVINE PAPILLOMAVIRUS, REPLICATION INITIATION, EARLY PROTEIN, TRANSCRIPTION, REDOX CONTROL, E1, E2, OXIDATION, ACTIVATOR, REPRESSOR, DNA-BINDING ;; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2jex__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2jex__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2jex__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)21.47 Å
Rg (electron density)20.63 Å
Total Rg21.44 Å
Atom count1572
Residues197
Excluded volume27606 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2jex__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2jexa_
Class classb — All beta proteins
Fold Fold foldb.91 — E2 regulatory, transactivation domain
Superfamily Superfamily superfamilyb.91.1 — E2 regulatory, transactivation domain
Family Family familyb.91.1.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id2jexA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily30 — E2 (early) protein, N terminal domain, subdomain 1
Domain ID domain_id2jexA02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology200 — Regulatory Protein E2; Chain: A; Domain 2
Homologous superfamily homologous superfamily10 — Papillomavirus E2 early protein domain
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7. Citations (1)