2jfd
Structure of the MAT domain of human FAS
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 2jfd |
| 沉积日期 deposition_date | 2007-01-31 |
| 结构标题 title | Structure of the MAT domain of human FAS |
| 关键词 keywords | TRANSFERASE, OXIDOREDUCTASE, LIPID SYNTHESIS, FATTY ACID BIOSYNTHESIS; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 69.97 Å |
| 回转半径 Rg (电子) rg_electron | 71.25 Å |
| 零角强度 I(0) i0 | 376215000.00 |
| 分子量 molecular_weight | 161450.0 kDa |
| 排除体积 excluded_volume | 201790 ų |
| 包络体积 envelope_volume | 314810 ų |
| 水化壳体积 shell_volume | 45066 ų |
| 包络直径 envelope_diameter | 244.0 Å |
| 壳层 Rg shell_rg | 49.24 Å |
| 包络 Rg envelope_rg | 70.82 Å |
| 形状 Rg shape_rg | 71.28 Å |
| 总 Rg total_rg | 70.52 Å |
| 总原子数 total_atoms | 11370 |
| 残基数 n_residues | 1606 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 214.9 Å |
| Rg (实空间) rg_real | 70.49 Å |
| Rg 误差 (实空间) rg_real_error | 2.21 Å |
| I(0) (实空间) i0_real | 3.7550e+08 |
| I(0) 误差 (实空间) i0_real_error | 9.1130e+06 |
| Rg (倒空间) rg_reciprocal | 66.35 Å |
| I(0) (倒空间) i0_reciprocal | 373000000.0000 |
| 解质量估计 total_estimate | 0.6932 |
| 解质量评级 solution_quality | REASONABLE a REASONABLE solution |
| P(r) 峰数 n_peaks | 3 |
| 主峰位置 r_peak_primary | 39.1 Å |
| 偏度 Skewness skewness | 0.547 |
| 峰度 Kurtosis kurtosis | -0.689 |
| 角度范围 angular_range | — – 0.1100 Å−1 |
| 当前正则化参数 α current_alpha | 0.0031 |
| 最高正则化参数 α highest_alpha | 6001000.0000 |
| 实空间数据点数 n_real_points | 23 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 0.302; Stabil: 0.994; Sysdev: 1.000; Positv: 1.000; Valcen: 0.331; Smooth: 0.784 |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合体信息 (2)
6. 折叠分类 (SCOP + CATH) 32 domains
SCOP 2.08 (20 domains)
| 结构域编号 domain_id | d2jfda1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | d.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | d.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfda2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfda3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfda4 |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | j.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | j.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfda5 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2jfdb1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | d.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | d.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdb2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdb3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdb4 |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | j.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | j.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdb5 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2jfdc1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | d.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | d.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdc2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdc3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdc4 |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | j.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | j.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdc5 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2jfdd1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | d.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | d.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdd2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdd3 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.19 — FabD/lysophospholipase-like |
| 超家族 Superfamily superfamily | c.19.1 — FabD/lysophospholipase-like |
| 家族 Family family | c.19.1.1 — FabD-like |
| 结构域编号 domain_id | d2jfdd4 |
| 类 Class class | j — Peptides |
| 折叠类型 Fold fold | j.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 超家族 Superfamily superfamily | j.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 家族 Family family | j.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like |
| 结构域编号 domain_id | d2jfdd5 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
CATH v4.4 (12 domains)
| 结构域编号 domain_id | 2jfdA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 3290 — |
| 结构域编号 domain_id | 2jfdA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 |
| 结构域编号 domain_id | 2jfdA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 250 — Malonyl-CoA ACP transacylase, ACP-binding |
| 结构域编号 domain_id | 2jfdB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 3290 — |
| 结构域编号 domain_id | 2jfdB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 |
| 结构域编号 domain_id | 2jfdB03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 250 — Malonyl-CoA ACP transacylase, ACP-binding |
| 结构域编号 domain_id | 2jfdC01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 3290 — |
| 结构域编号 domain_id | 2jfdC02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 |
| 结构域编号 domain_id | 2jfdC03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 250 — Malonyl-CoA ACP transacylase, ACP-binding |
| 结构域编号 domain_id | 2jfdD01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 3290 — |
| 结构域编号 domain_id | 2jfdD02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 |
| 结构域编号 domain_id | 2jfdD03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 70 — Alpha-Beta Plaits |
| 同源超家族 H-superfamily homologous superfamily | 250 — Malonyl-CoA ACP transacylase, ACP-binding |