2jfd

Structure of the MAT domain of human FAS

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

FATTY ACID SYNTHASE

HOMO SAPIENS

UniProt P49327

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白单体 单体 蛋白 1 water × 1 与蛋白数一致
2 蛋白单体 单体 蛋白 1 water × 1 与蛋白数一致
3 蛋白单体 单体 蛋白 1 water × 1 与蛋白数一致
4 蛋白单体 单体 蛋白 1 无其他共同聚合物 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 FAS_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 24–425; UniProt 422–823 作者链 B; PDB构建体 24–425; UniProt 422–823 作者链 C; PDB构建体 24–425; UniProt 422–823 作者链 D; PDB构建体 24–425; UniProt 422–823

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2jfd
沉积日期 deposition_date2007-01-31
结构标题 titleStructure of the MAT domain of human FAS
关键词 keywordsTRANSFERASE, OXIDOREDUCTASE, LIPID SYNTHESIS, FATTY ACID BIOSYNTHESIS; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2jfd__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2jfd__assembly_3__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2jfd__assembly_3__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)22.50 Å
Rg(电子密度)21.68 Å
总 Rg22.47 Å
原子数2892
残基数403
排除体积51562 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2jfd__assembly_1__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2jfd__assembly_2__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 2jfd__assembly_3__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 2jfd__assembly_4__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 32 domains

SCOP 2.08 (20 domains)

结构域编号 domain_idd2jfda1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyd.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyd.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfda2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfda3
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfda4
类 Class classj — Peptides
折叠类型 Fold foldj.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyj.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyj.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfda5
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2jfdb1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyd.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyd.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdb2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdb3
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdb4
类 Class classj — Peptides
折叠类型 Fold foldj.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyj.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyj.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdb5
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2jfdc1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyd.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyd.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdc2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdc3
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdc4
类 Class classj — Peptides
折叠类型 Fold foldj.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyj.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyj.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdc5
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2jfdd1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.390 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyd.390.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyd.390.1.1 — KS-to-AT linker domain from 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdd2
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdd3
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.19 — FabD/lysophospholipase-like
超家族 Superfamily superfamilyc.19.1 — FabD/lysophospholipase-like
家族 Family familyc.19.1.1 — FabD-like
结构域编号 domain_idd2jfdd4
类 Class classj — Peptides
折叠类型 Fold foldj.134 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
超家族 Superfamily superfamilyj.134.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
家族 Family familyj.134.1.1 — C-terminal linker of 6-deoxyerythronolide B synthase (DEBS)-like
结构域编号 domain_idd2jfdd5
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags

CATH v4.4 (12 domains)

结构域编号 domain_id2jfdA01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily3290 —
结构域编号 domain_id2jfdA02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
结构域编号 domain_id2jfdA03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily250 — Malonyl-CoA ACP transacylase, ACP-binding
结构域编号 domain_id2jfdB01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily3290 —
结构域编号 domain_id2jfdB02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
结构域编号 domain_id2jfdB03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily250 — Malonyl-CoA ACP transacylase, ACP-binding
结构域编号 domain_id2jfdC01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily3290 —
结构域编号 domain_id2jfdC02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
结构域编号 domain_id2jfdC03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily250 — Malonyl-CoA ACP transacylase, ACP-binding
结构域编号 domain_id2jfdD01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily3290 —
结构域编号 domain_id2jfdD02
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology366 — Malonyl-Coenzyme A Acyl Carrier Protein; domain 2
同源超家族 H-superfamily homologous superfamily10 — Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
结构域编号 domain_id2jfdD03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily250 — Malonyl-CoA ACP transacylase, ACP-binding
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7. 引用文献 (1)